AutismKB 2.0

Annotation Detail for TBL3


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Basic Information Top
Gene Symbol:TBL3 ( SAZD )
Gene Full Name: transducin (beta)-like 3
Band: 16p13.3
Quick LinksEntrez ID:10607; OMIM: 605915; Uniprot ID:TBL3_HUMAN; ENSEMBL ID: ENSG00000183751; HGNC ID: 11587
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst6 / 6231996
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult116 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor42 / 119369351
germ cell tumor14 / 26384553
glioma16 / 106883149
head and neck tumor2 / 13630214
kidney tumor5 / 6895972
leukemia5 / 9584252
liver tumor0 / 963590 
lung tumor19 / 103127184
lymphoma18 / 71755250
non-neoplasia3 / 9725030
normal98 / 336030729
ovarian tumor9 / 76682117
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS24 / 125680190
prostate cancer2 / 10268019
retinoblastoma11 / 46356237
skin tumor30 / 124949240
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites16 / 40015399
bladder0 / 297570 
blood5 / 12347840
bone5 / 7165569
bone marrow1 / 4880120
brain39 / 110098935
cervix5 / 48171103
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye23 / 211054108
heart1 / 8962611
intestine11 / 23447246
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung24 / 33697471
lymph12 / 44270271
lymph node23 / 91610251
mammary gland3 / 15327119
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary14 / 102051137
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta23 / 28082581
prostate2 / 18934510
salivary gland1 / 2015549
skin33 / 210574156
spleen2 / 5395237
stomach7 / 9661972
testis18 / 33044254
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209820_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts48.95
Adipocyte4.9
AdrenalCortex5.35
Adrenalgland4.45
Amygdala6.1
Appendix4.9
AtrioventricularNode3.9
BDCA4+_DentriticCells18.65
Bonemarrow5.15
BronchialEpithelialCells9.25
CD105+_Endothelial36.5
CD14+_Monocytes24.05
CD19+_BCells(neg._sel.)15.35
CD33+_Myeloid9.5
CD34+25.25
CD4+_Tcells17.3
CD56+_NKCells16.8
CD71+_EarlyErythroid9.15
CD8+_Tcells20.75
CardiacMyocytes7
Caudatenucleus5.1
Cerebellum4.3
CerebellumPeduncles8.85
CiliaryGanglion3.65
CingulateCortex5.15
Colorectaladenocarcinoma18.6
DorsalRootGanglion3.95
FetalThyroid7.4
Fetalbrain4.95
Fetalliver4.35
Fetallung5.15
GlobusPallidus3.65
Heart32.45
Hypothalamus6.2
Kidney4.15
Leukemia_chronicMyelogenousK-56219.35
Leukemia_promyelocytic-HL-6014.6
Leukemialymphoblastic(MOLT-4)5.2
Liver46.25
Lung51.85
Lymphnode4.25
Lymphoma_burkitts(Daudi)9.9
Lymphoma_burkitts(Raji)24.9
MedullaOblongata4.35
OccipitalLobe4.6
OlfactoryBulb3.9
Ovary3.35
Pancreas4.8
PancreaticIslet6.75
ParietalLobe5.35
Pituitary5.85
Placenta6.55
Pons4.9
PrefrontalCortex6.5
Prostate39.45
Salivarygland4.15
SkeletalMuscle5.7
Skin3.95
SmoothMuscle7.15
Spinalcord5.8
SubthalamicNucleus4.55
SuperiorCervicalGanglion5.85
TemporalLobe4.5
Testis47.2
TestisGermCell7.35
TestisIntersitial8.9
TestisLeydigCell5.2
TestisSeminiferousTubule11.1
Thalamus5.45
Thymus6.4
Thyroid38.05
Tongue5.1
Tonsil4.85
Trachea4.15
TrigeminalGanglion5.05
Uterus10.05
UterusCorpus4.35
WholeBlood5.65
Wholebrain9.2
colon5.35
pineal_day9.84
pineal_night8.34
retina8.35
small_intestine5.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_692_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.31 ± 0.39
Basal Forebrain5.09 ± 0.23
Basal Part of Pons5.16 ± 0.27
Cerebellar Cortex5.02 ± 0.39
Cerebellar Nuclei5.17 ± 0.48
Claustrum5.43 ± 0.6
Epithalamus4.46 ± 0.43
Frontal Lobe5.1 ± 0.45
Globus Pallidus5.23 ± 0.22
Hypothalamus4.99 ± 0.32
Insula5.01 ± 0.41
Limbic Lobe5.13 ± 0.42
Mesencephalon5.2 ± 0.42
Myelencephalon5.11 ± 0.44
Occipital Lobe4.95 ± 0.52
Parietal Lobe5.03 ± 0.42
Pontine Tegmentum4.93 ± 0.41
Striatum5.1 ± 0.43
Subthalamus5 ± 0.03
Temporal Lobe5.02 ± 0.44
Thalamus5.1 ± 0.4
White Matter5.5 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tbl3CBCerebellum12.89
19.3
Tbl3CTXCerebral cortex42.74
34.91
Tbl3HIPHippocampal region39.42
50
Tbl3HPFHippocampal formation44.22
50
Tbl3HYHypothalamus23.92
18.92
Tbl3LSXLateral septal complex39.16
32.07
Tbl3MBMidbrain41.06
42.04
Tbl3MYMedulla29.84
37.91
Tbl3OLFOlfactory bulb41.09
34.8
Tbl3PPons45.01
50
Tbl3PALPallidum25.51
21.89
Tbl3RHPRetrohippocampal region50
47.77
Tbl3sAMYStriatum-like amygdalar nuclei21.94
16.07
Tbl3STRStriatum28.54
20.97
Tbl3STRdStriatum dorsal region29.45
21.54
Tbl3STRvStriatum ventral region24.51
17.59
Tbl3THThalamus31.42
25.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001050 25 477 501 CHDKDINSVAIAPNDKLLATGSQDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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