Annotation Detail for CENPE
Basic Information Top
| Gene Symbol: | CENPE ( KIF10 ) |
|---|---|
| Gene Full Name: | centromere protein E, 312kDa |
| Band: | 4q24 |
| Quick Links | Entrez ID:1062; OMIM: 117143; Uniprot ID:CENPE_HUMAN; ENSEMBL ID: ENSG00000138778; HGNC ID: 1856 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.75573
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 7 / 62319 | 112 |  |
| fetus | 43 / 564012 | 76 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 2 / 55556 | 35 | |
| adult | 36 / 1939121 | 18 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 2 / 12794 | 156 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 80 / 3360307 | 23 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 3 / 102680 | 29 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 9 / 125191 | 71 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 2 / 33197 | 60 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 5 / 1100989 | 4 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 12 / 215722 | 55 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 1 / 89626 | 11 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 6 / 207743 | 28 | |
| lung | 6 / 336974 | 17 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 15 / 91610 | 163 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 5 / 210574 | 23 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 7 / 330442 | 21 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205046_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 83.05 | |
| Adipocyte | 3.7 | |
| AdrenalCortex | 3.9 | |
| Adrenalgland | 3.1 | |
| Amygdala | 3.9 | |
| Appendix | 3.8 | |
| AtrioventricularNode | 2.85 | |
| BDCA4+_DentriticCells | 4.1 | |
| Bonemarrow | 3.65 | |
| BronchialEpithelialCells | 3.65 | |
| CD105+_Endothelial | 27.25 | |
| CD14+_Monocytes | 4 | |
| CD19+_BCells(neg._sel.) | 3.95 | |
| CD33+_Myeloid | 4.9 | |
| CD34+ | 8.4 | |
| CD4+_Tcells | 4.05 | |
| CD56+_NKCells | 4.5 | |
| CD71+_EarlyErythroid | 112.55 | |
| CD8+_Tcells | 3.6 | |
| CardiacMyocytes | 10.75 | |
| Caudatenucleus | 3.35 | |
| Cerebellum | 3 | |
| CerebellumPeduncles | 4.2 | |
| CiliaryGanglion | 2.65 | |
| CingulateCortex | 3.8 | |
| Colorectaladenocarcinoma | 4 | |
| DorsalRootGanglion | 3.5 | |
| FetalThyroid | 3.6 | |
| Fetalbrain | 3.7 | |
| Fetalliver | 3.25 | |
| Fetallung | 3.05 | |
| GlobusPallidus | 2.75 | |
| Heart | 4.75 | |
| Hypothalamus | 4.05 | |
| Kidney | 3 | |
| Leukemia_chronicMyelogenousK-562 | 4.3 | |
| Leukemia_promyelocytic-HL-60 | 11.5 | |
| Leukemialymphoblastic(MOLT-4) | 31.8 | |
| Liver | 4.9 | |
| Lung | 4.1 | |
| Lymphnode | 3.15 | |
| Lymphoma_burkitts(Daudi) | 31.9 | |
| Lymphoma_burkitts(Raji) | 5.2 | |
| MedullaOblongata | 3.4 | |
| OccipitalLobe | 3.35 | |
| OlfactoryBulb | 2.95 | |
| Ovary | 2.45 | |
| Pancreas | 3 | |
| PancreaticIslet | 3.95 | |
| ParietalLobe | 3.9 | |
| Pituitary | 4.35 | |
| Placenta | 3.85 | |
| Pons | 3.5 | |
| PrefrontalCortex | 4.6 | |
| Prostate | 4.3 | |
| Salivarygland | 3 | |
| SkeletalMuscle | 4.45 | |
| Skin | 2.95 | |
| SmoothMuscle | 4.25 | |
| Spinalcord | 4 | |
| SubthalamicNucleus | 3.4 | |
| SuperiorCervicalGanglion | 4.3 | |
| TemporalLobe | 3.4 | |
| Testis | 3.2 | |
| TestisGermCell | 3.2 | |
| TestisIntersitial | 3.15 | |
| TestisLeydigCell | 3.7 | |
| TestisSeminiferousTubule | 3.2 | |
| Thalamus | 3.8 | |
| Thymus | 2.95 | |
| Thyroid | 4.65 | |
| Tongue | 3.7 | |
| Tonsil | 3.6 | |
| Trachea | 3.1 | |
| TrigeminalGanglion | 3.75 | |
| Uterus | 3.05 | |
| UterusCorpus | 3.4 | |
| WholeBlood | 4.05 | |
| Wholebrain | 3.15 | |
| colon | 3.7 | |
| pineal_day | 4.64 | |
| pineal_night | 4.56 | |
| retina | 4.475 | |
| small_intestine | 3.6 | |
- Probe name: CUST_11676_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.14 ± 0.98 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.15 ± 0.36 | |
| Basal Part of Pons | 2.93 ± 0.65 | |
| Cerebellar Cortex | 2.48 ± 0.5 | |
| Cerebellar Nuclei | 3.19 ± 0.86 | |
| Claustrum | 3.49 ± 0.79 | |
| Epithalamus | 2.66 ± 0.85 | |
| Frontal Lobe | 3.17 ± 0.78 | |
| Globus Pallidus | 3.14 ± 0.69 | |
| Hypothalamus | 3.36 ± 0.45 | |
| Insula | 3.31 ± 1.06 | |
| Limbic Lobe | 3.12 ± 0.68 | |
| Mesencephalon | 3.05 ± 0.76 | |
| Myelencephalon | 3.14 ± 0.76 | |
| Occipital Lobe | 2.8 ± 0.74 | |
| Parietal Lobe | 2.82 ± 0.78 | |
| Pontine Tegmentum | 3.19 ± 0.91 | |
| Striatum | 3.4 ± 0.83 | |
| Subthalamus | 2.98 ± 0.75 | |
| Temporal Lobe | 3.12 ± 0.75 | |
| Thalamus | 2.99 ± 0.64 | |
| White Matter | 3.17 ± 0.74 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cenpe | CB | Cerebellum | 1.09 | |
| 1.82 | | |||
| Cenpe | CTX | Cerebral cortex | 1.13 | |
| 1.18 | | |||
| Cenpe | HIP | Hippocampal region | 1.24 | |
| 1.33 | | |||
| Cenpe | HPF | Hippocampal formation | 1.43 | |
| 1.34 | | |||
| Cenpe | HY | Hypothalamus | 0.27 | |
| 0.34 | | |||
| Cenpe | LSX | Lateral septal complex | 0.29 | |
| 0.2 | | |||
| Cenpe | MB | Midbrain | 0.29 | |
| 0.43 | | |||
| Cenpe | MY | Medulla | 0.73 | |
| 0.98 | | |||
| Cenpe | OLF | Olfactory bulb | 2.69 | |
| 3.41 | | |||
| Cenpe | P | Pons | 0.45 | |
| 0.63 | | |||
| Cenpe | PAL | Pallidum | 0.19 | |
| 0.19 | | |||
| Cenpe | RHP | Retrohippocampal region | 1.72 | |
| 1.32 | | |||
| Cenpe | sAMY | Striatum-like amygdalar nuclei | 0.37 | |
| 0.35 | | |||
| Cenpe | STR | Striatum | 0.75 | |
| 0.88 | | |||
| Cenpe | STRd | Striatum dorsal region | 0.83 | |
| 1.05 | | |||
| Cenpe | STRv | Striatum ventral region | 0.44 | |
| 0.41 | | |||
| Cenpe | TH | Thalamus | 0.32 | |
| 0.36 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CENPE_HUMAN_1207 | 10 | 1207 | 1216 | ELQKSFETER | PRIDE |
| CENPE_HUMAN_1261 | 12 | 1261 | 1272 | TAQIINTQDLEK | PRIDE |
| CENPE_HUMAN_2592 | 12 | 2592 | 2603 | NLQDPVPKESPK | PRIDE |
| CENPE_HUMAN_2611 | 11 | 2611 | 2621 | SKSLPSPHPVR | PRIDE |
| CENPE_HUMAN_35 | 8 | 35 | 42 | NNVIYQVD | PRIDE |
| CENPE_HUMAN_350 | 7 | 350 | 356 | KEIMDLK | PRIDE |
| CENPE_HUMAN_420 | 8 | 420 | 427 | RVTWCLGK | PRIDE |
| CENPE_HUMAN_450 | 10 | 450 | 459 | THKLSINLLR | PRIDE |
| CENPE_HUMAN_608 | 14 | 608 | 621 | MDLSYSLESIEDPK | PRIDE |