AutismKB 2.0

Annotation Detail for GAS2L1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GAS2L1 ( GAR22,MGC17243 )
Gene Full Name: growth arrest-specific 2 like 1
Band: 22q12.2
Quick LinksEntrez ID:10634; OMIM: 602128; Uniprot ID:GA2L1_HUMAN; ENSEMBL ID: ENSG00000185340; HGNC ID: 16955
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile7 / 55556125
adult62 / 193912131
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor7 / 26384526
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia17 / 95842177
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal126 / 336030737
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder0 / 297570 
blood18 / 123478145
bone2 / 7165527
bone marrow2 / 4880140
brain53 / 110098948
cervix2 / 4817141
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus3 / 20209148
eye9 / 21105442
heart2 / 8962622
intestine8 / 23447234
kidney9 / 21177742
larynx1 / 2414541
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland11 / 15327171
mouth2 / 6705229
muscle0 / 1077150 
nerve2 / 15768126
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta19 / 28082567
prostate5 / 18934526
salivary gland2 / 2015599
skin4 / 21057418
spleen5 / 5395292
stomach1 / 9661910
testis21 / 33044263
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 31874_at
Cell line Expression level Expression bar
721_B_lymphoblasts8
Adipocyte29.9
AdrenalCortex72.35
Adrenalgland90.75
Amygdala215.35
Appendix18.95
AtrioventricularNode14.3
BDCA4+_DentriticCells15.85
Bonemarrow38.25
BronchialEpithelialCells76.65
CD105+_Endothelial513.55
CD14+_Monocytes66.35
CD19+_BCells(neg._sel.)13.35
CD33+_Myeloid46.9
CD34+32.45
CD4+_Tcells7.05
CD56+_NKCells12.1
CD71+_EarlyErythroid103.85
CD8+_Tcells6
CardiacMyocytes50.1
Caudatenucleus86.5
Cerebellum57.9
CerebellumPeduncles54.2
CiliaryGanglion14.75
CingulateCortex152
Colorectaladenocarcinoma25.85
DorsalRootGanglion17.35
FetalThyroid26.75
Fetalbrain52.05
Fetalliver14.15
Fetallung20.15
GlobusPallidus41
Heart211.1
Hypothalamus129.9
Kidney16.8
Leukemia_chronicMyelogenousK-5629.2
Leukemia_promyelocytic-HL-608.25
Leukemialymphoblastic(MOLT-4)12
Liver47.65
Lung256.65
Lymphnode14.5
Lymphoma_burkitts(Daudi)12.45
Lymphoma_burkitts(Raji)16.4
MedullaOblongata115.7
OccipitalLobe83.95
OlfactoryBulb148.7
Ovary6.15
Pancreas10.3
PancreaticIslet13.7
ParietalLobe95.25
Pituitary99.55
Placenta37.1
Pons56.1
PrefrontalCortex253.7
Prostate215.1
Salivarygland12.45
SkeletalMuscle17.2
Skin19.35
SmoothMuscle44.5
Spinalcord158.05
SubthalamicNucleus76
SuperiorCervicalGanglion19.6
TemporalLobe125.85
Testis289.9
TestisGermCell249.8
TestisIntersitial51.7
TestisLeydigCell27.9
TestisSeminiferousTubule115.95
Thalamus89
Thymus10.85
Thyroid55.7
Tongue52.8
Tonsil17.85
Trachea16.5
TrigeminalGanglion27.4
Uterus46.65
UterusCorpus23.4
WholeBlood71.9
Wholebrain291.65
colon26.05
pineal_day94.76
pineal_night101.06
retina50.025
small_intestine28
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P103041
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.99 ± 0.77
Basal Forebrain2.48 ± 0.4
Basal Part of Pons2.82 ± 0.4
Cerebellar Cortex2.6 ± 0.66
Cerebellar Nuclei2.96 ± 0.47
Claustrum3.15 ± 0.92
Epithalamus2.65 ± 0.63
Frontal Lobe2.99 ± 0.63
Globus Pallidus2.69 ± 0.88
Hypothalamus2.6 ± 0.74
Insula2.62 ± 0.74
Limbic Lobe2.95 ± 0.66
Mesencephalon2.99 ± 0.79
Myelencephalon2.93 ± 0.65
Occipital Lobe2.67 ± 0.6
Parietal Lobe3.06 ± 0.7
Pontine Tegmentum2.84 ± 0.67
Striatum2.8 ± 0.69
Subthalamus2.48 ± 0.54
Temporal Lobe3.06 ± 0.6
Thalamus2.87 ± 0.6
White Matter1.97 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gas2l1CBCerebellum8.95
9.61
Gas2l1CTXCerebral cortex23.89
18.35
Gas2l1HIPHippocampal region27.97
30
Gas2l1HPFHippocampal formation24.28
23.36
Gas2l1HYHypothalamus10.32
8.2
Gas2l1LSXLateral septal complex11.84
8.58
Gas2l1MBMidbrain9.06
8.65
Gas2l1MYMedulla19.25
21.6
Gas2l1OLFOlfactory bulb33.55
26.46
Gas2l1PPons13.01
15.27
Gas2l1PALPallidum9.87
8.65
Gas2l1RHPRetrohippocampal region18.02
14.21
Gas2l1sAMYStriatum-like amygdalar nuclei10.49
7.33
Gas2l1STRStriatum12.08
10.39
Gas2l1STRdStriatum dorsal region11.81
11.51
Gas2l1STRvStriatum ventral region14.28
9.75
Gas2l1THThalamus10.17
8.53
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved