AutismKB 2.0

Annotation Detail for MTX2


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Basic Information Top
Gene Symbol:MTX2 ( MGC111067 )
Gene Full Name: metaxin 2
Band: 2q31.1
Quick LinksEntrez ID:10651; OMIM: 608555; Uniprot ID:MTX2_HUMAN; ENSEMBL ID: ENSG00000128654; HGNC ID: 7506
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst5 / 6231980
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor6 / 10312758
lymphoma5 / 7175569
non-neoplasia2 / 9725020
normal100 / 336030729
ovarian tumor4 / 7668252
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma3 / 4635664
skin tumor5 / 12494940
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder1 / 2975733
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain26 / 110098923
cervix1 / 4817120
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue12 / 21572255
esophagus1 / 2020949
eye9 / 21105442
heart2 / 8962622
intestine3 / 23447212
kidney13 / 21177761
larynx0 / 241450 
liver1 / 2077434
lung15 / 33697444
lymph2 / 4427045
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle7 / 10771564
nerve0 / 157680 
ovary5 / 10205148
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate5 / 18934526
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach5 / 9661951
testis21 / 33044263
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203517_at
Cell line Expression level Expression bar
721_B_lymphoblasts140.8
Adipocyte12.45
AdrenalCortex12
Adrenalgland13.65
Amygdala39.95
Appendix11.55
AtrioventricularNode8.75
BDCA4+_DentriticCells15.6
Bonemarrow10.2
BronchialEpithelialCells57.8
CD105+_Endothelial27.2
CD14+_Monocytes12.15
CD19+_BCells(neg._sel.)14.85
CD33+_Myeloid10.65
CD34+31
CD4+_Tcells15.75
CD56+_NKCells15.1
CD71+_EarlyErythroid9.85
CD8+_Tcells14.7
CardiacMyocytes17.15
Caudatenucleus11.75
Cerebellum8.95
CerebellumPeduncles13.1
CiliaryGanglion8.15
CingulateCortex19.3
Colorectaladenocarcinoma20.2
DorsalRootGanglion9.65
FetalThyroid11.85
Fetalbrain32.7
Fetalliver9.95
Fetallung10.85
GlobusPallidus9.3
Heart15.25
Hypothalamus36.8
Kidney10.85
Leukemia_chronicMyelogenousK-56265.8
Leukemia_promyelocytic-HL-6055.9
Leukemialymphoblastic(MOLT-4)20.6
Liver14.25
Lung13.4
Lymphnode9.9
Lymphoma_burkitts(Daudi)41.45
Lymphoma_burkitts(Raji)57.05
MedullaOblongata12.85
OccipitalLobe16.95
OlfactoryBulb9.25
Ovary7.45
Pancreas11.95
PancreaticIslet16.5
ParietalLobe14.9
Pituitary16.25
Placenta15.75
Pons12.1
PrefrontalCortex32.65
Prostate18.35
Salivarygland10.3
SkeletalMuscle13.25
Skin9.45
SmoothMuscle31.2
Spinalcord19.8
SubthalamicNucleus13.35
SuperiorCervicalGanglion12.9
TemporalLobe11.4
Testis76.9
TestisGermCell70.4
TestisIntersitial66.1
TestisLeydigCell51.55
TestisSeminiferousTubule54.25
Thalamus23.2
Thymus8.75
Thyroid23.1
Tongue11.2
Tonsil11.1
Trachea7.85
TrigeminalGanglion11.45
Uterus10.3
UterusCorpus11.4
WholeBlood10.2
Wholebrain45.35
colon29.25
pineal_day68.86
pineal_night48.54
retina20.475
small_intestine18.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P120335
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.76 ± 0.33
Basal Forebrain8.7 ± 0.24
Basal Part of Pons9.31 ± 0.13
Cerebellar Cortex8.92 ± 0.24
Cerebellar Nuclei9.39 ± 0.25
Claustrum8.85 ± 0.4
Epithalamus8.83 ± 0.33
Frontal Lobe9.23 ± 0.28
Globus Pallidus8.62 ± 0.32
Hypothalamus9.19 ± 0.17
Insula9.14 ± 0.45
Limbic Lobe8.93 ± 0.43
Mesencephalon8.93 ± 0.35
Myelencephalon9 ± 0.41
Occipital Lobe8.71 ± 0.45
Parietal Lobe9.08 ± 0.37
Pontine Tegmentum9.05 ± 0.35
Striatum8.61 ± 0.44
Subthalamus9.38 ± 0.21
Temporal Lobe9.16 ± 0.29
Thalamus9.04 ± 0.25
White Matter9.09 ± 0.21
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002866 13 96 108 GHSLSDGLEEVQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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