AutismKB 2.0

Annotation Detail for GNA13


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Basic Information Top
Gene Symbol:GNA13 ( G13,MGC46138 )
Gene Full Name: guanine nucleotide binding protein (G protein), alpha 13
Band: 17q24.1
Quick LinksEntrez ID:10672; OMIM: 604406; Uniprot ID:GNA13_HUMAN; ENSEMBL ID: ENSG00000120063; HGNC ID: 4381
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst6 / 6231996
fetus35 / 56401262
neonate3 / 3109796
infant2 / 2362084
juvenile4 / 5555671
adult100 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor3 / 17290173
gastrointestinal tumor8 / 11936967
germ cell tumor17 / 26384564
glioma1 / 1068839
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor7 / 9635972
lung tumor6 / 10312758
lymphoma6 / 7175583
non-neoplasia2 / 9725020
normal228 / 336030767
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer7 / 10268068
retinoblastoma1 / 4635621
skin tumor14 / 124949112
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor13 / 90257144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood8 / 12347864
bone4 / 7165555
bone marrow5 / 48801102
brain74 / 110098967
cervix2 / 4817141
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue19 / 21572288
esophagus3 / 20209148
eye4 / 21105418
heart0 / 896260 
intestine9 / 23447238
kidney13 / 21177761
larynx0 / 241450 
liver10 / 20774348
lung16 / 33697447
lymph1 / 4427022
lymph node23 / 91610251
mammary gland4 / 15327126
mouth7 / 67052104
muscle9 / 10771583
nerve3 / 15768190
ovary4 / 10205139
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta24 / 28082585
prostate8 / 18934542
salivary gland1 / 2015549
skin20 / 21057494
spleen5 / 5395292
stomach6 / 9661962
testis22 / 33044266
thymus17 / 81131209
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus19 / 23287881
vascular5 / 5178096
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206917_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.7
Adipocyte4.65
AdrenalCortex5.15
Adrenalgland4.05
Amygdala4.85
Appendix4.9
AtrioventricularNode3.8
BDCA4+_DentriticCells10.1
Bonemarrow4.85
BronchialEpithelialCells4.65
CD105+_Endothelial4.75
CD14+_Monocytes5
CD19+_BCells(neg._sel.)5.15
CD33+_Myeloid6.1
CD34+6.05
CD4+_Tcells6
CD56+_NKCells6.55
CD71+_EarlyErythroid5.25
CD8+_Tcells7.25
CardiacMyocytes6.55
Caudatenucleus4.25
Cerebellum3.85
CerebellumPeduncles5.45
CiliaryGanglion3.4
CingulateCortex4.9
Colorectaladenocarcinoma4.75
DorsalRootGanglion3.75
FetalThyroid4.6
Fetalbrain4.65
Fetalliver4.15
Fetallung3.8
GlobusPallidus3.5
Heart6.5
Hypothalamus5.05
Kidney4
Leukemia_chronicMyelogenousK-5624.3
Leukemia_promyelocytic-HL-604.15
Leukemialymphoblastic(MOLT-4)3.75
Liver6.55
Lung5.15
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)6.85
MedullaOblongata4.4
OccipitalLobe4.25
OlfactoryBulb3.7
Ovary3.2
Pancreas3.85
PancreaticIslet5.05
ParietalLobe5.1
Pituitary5.5
Placenta4.95
Pons4.5
PrefrontalCortex5.75
Prostate5.45
Salivarygland3.85
SkeletalMuscle5.95
Skin3.7
SmoothMuscle5.35
Spinalcord5.05
SubthalamicNucleus4.4
SuperiorCervicalGanglion5.85
TemporalLobe4.3
Testis4
TestisGermCell3.85
TestisIntersitial3.95
TestisLeydigCell4.7
TestisSeminiferousTubule4.05
Thalamus4.8
Thymus3.65
Thyroid5.8
Tongue4.75
Tonsil4.65
Trachea3.95
TrigeminalGanglion4.8
Uterus3.8
UterusCorpus4.55
WholeBlood6.5
Wholebrain3.85
colon5.1
pineal_day9.52
pineal_night5.76
retina5.7
small_intestine4.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P150874
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.78 ± 0.54
Basal Forebrain6.04 ± 0.29
Basal Part of Pons4.85 ± 0.32
Cerebellar Cortex5.79 ± 0.28
Cerebellar Nuclei5.51 ± 0.5
Claustrum5.54 ± 0.58
Epithalamus6.24 ± 0.3
Frontal Lobe5.47 ± 0.45
Globus Pallidus6.68 ± 0.57
Hypothalamus5.8 ± 0.36
Insula5.65 ± 0.29
Limbic Lobe5.4 ± 0.48
Mesencephalon5.87 ± 0.37
Myelencephalon5.69 ± 0.54
Occipital Lobe5.92 ± 0.4
Parietal Lobe5.59 ± 0.47
Pontine Tegmentum5.74 ± 0.39
Striatum6.11 ± 0.52
Subthalamus5.19 ± 0.16
Temporal Lobe5.43 ± 0.37
Thalamus5.74 ± 0.37
White Matter6.27 ± 0.07
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gna13CBCerebellum5.77
7.48
Gna13CTXCerebral cortex0.85
0.99
Gna13HIPHippocampal region0.44
0.45
Gna13HPFHippocampal formation0.49
0.51
Gna13HYHypothalamus0.16
0.17
Gna13LSXLateral septal complex0.16
0.12
Gna13MBMidbrain0.55
0.78
Gna13MYMedulla1.45
2.12
Gna13OLFOlfactory bulb0.48
0.47
Gna13PPons0.51
0.74
Gna13PALPallidum0.54
0.76
Gna13RHPRetrohippocampal region0.58
0.59
Gna13sAMYStriatum-like amygdalar nuclei0.08
0.13
Gna13STRStriatum0.47
0.63
Gna13STRdStriatum dorsal region0.6
0.92
Gna13STRvStriatum ventral region0.23
0.2
Gna13THThalamus0.56
0.84
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GNA13_HUMAN_128 12 128 139 APMAAQGMVETR PRIDE
GNA13_HUMAN_140 10 140 149 VFLQYLPAIR PRIDE
GNA13_HUMAN_50 11 50 60 ILLLGAGESGK PRIDE
PAp00001839 12 361 372 DVKDTILHDNLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018