AutismKB 2.0

Annotation Detail for CCT6B


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Basic Information Top
Gene Symbol:CCT6B ( CCT-zeta-2,CCTZ-2,Cctz2,TCP-1-zeta-2,TSA303 )
Gene Full Name: chaperonin containing TCP1, subunit 6B (zeta 2)
Band: 17q12
Quick LinksEntrez ID:10693; OMIM: 610730; Uniprot ID:TCPW_HUMAN; ENSEMBL ID: ENSG00000132141; HGNC ID: 1621
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal167 / 336030749
ovarian tumor1 / 7668213
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain10 / 11009899
cervix1 / 4817120
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach4 / 9661941
testis160 / 330442484
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206587_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.65
Adipocyte3.6
AdrenalCortex3.8
Adrenalgland3.05
Amygdala3.85
Appendix3.75
AtrioventricularNode2.75
BDCA4+_DentriticCells4.4
Bonemarrow3.55
BronchialEpithelialCells3.65
CD105+_Endothelial3.7
CD14+_Monocytes4
CD19+_BCells(neg._sel.)3.95
CD33+_Myeloid4.7
CD34+12.25
CD4+_Tcells4
CD56+_NKCells4.6
CD71+_EarlyErythroid3.45
CD8+_Tcells3.55
CardiacMyocytes4.65
Caudatenucleus3.25
Cerebellum2.9
CerebellumPeduncles4.1
CiliaryGanglion2.55
CingulateCortex3.7
Colorectaladenocarcinoma3.7
DorsalRootGanglion2.75
FetalThyroid3.55
Fetalbrain3.6
Fetalliver3.15
Fetallung3.05
GlobusPallidus2.7
Heart4.7
Hypothalamus4
Kidney2.9
Leukemia_chronicMyelogenousK-5623.3
Leukemia_promyelocytic-HL-603.25
Leukemialymphoblastic(MOLT-4)2.9
Liver4.8
Lung4
Lymphnode3.15
Lymphoma_burkitts(Daudi)4.65
Lymphoma_burkitts(Raji)5.4
MedullaOblongata3.35
OccipitalLobe3.25
OlfactoryBulb2.85
Ovary2.45
Pancreas2.9
PancreaticIslet5.35
ParietalLobe3.85
Pituitary4.25
Placenta3.75
Pons3.45
PrefrontalCortex4.6
Prostate4.25
Salivarygland2.9
SkeletalMuscle4.15
Skin2.8
SmoothMuscle4.15
Spinalcord3.9
SubthalamicNucleus3.3
SuperiorCervicalGanglion4.05
TemporalLobe3.35
Testis153.4
TestisGermCell726.25
TestisIntersitial946.25
TestisLeydigCell582.85
TestisSeminiferousTubule462.4
Thalamus3.7
Thymus2.9
Thyroid4.6
Tongue3.55
Tonsil3.55
Trachea3
TrigeminalGanglion3.6
Uterus3
UterusCorpus3.25
WholeBlood4
Wholebrain3.05
colon3.65
pineal_day4.6
pineal_night4.46
retina4.425
small_intestine3.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13172_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.39 ± 0.55
Basal Forebrain4.51 ± 0.62
Basal Part of Pons4.15 ± 0.55
Cerebellar Cortex4.31 ± 0.5
Cerebellar Nuclei3.8 ± 0.62
Claustrum3.71 ± 0.82
Epithalamus4.98 ± 0.38
Frontal Lobe4.25 ± 0.48
Globus Pallidus5.18 ± 0.21
Hypothalamus4.41 ± 0.58
Insula4.21 ± 0.48
Limbic Lobe4.09 ± 0.46
Mesencephalon4.35 ± 0.51
Myelencephalon4.28 ± 0.58
Occipital Lobe3.87 ± 0.57
Parietal Lobe4.25 ± 0.5
Pontine Tegmentum4.08 ± 0.5
Striatum4.2 ± 0.53
Subthalamus4.15 ± 0.15
Temporal Lobe4.2 ± 0.46
Thalamus4.19 ± 0.54
White Matter5.4 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cct6bCBCerebellum0.41
1.06
Cct6bCTXCerebral cortex0.49
0.84
Cct6bHIPHippocampal region0.47
0.9
Cct6bHPFHippocampal formation0.38
0.61
Cct6bHYHypothalamus1.84
2.25
Cct6bLSXLateral septal complex0.22
0.17
Cct6bMBMidbrain0.16
0.37
Cct6bMYMedulla0.27
0.28
Cct6bOLFOlfactory bulb0.5
1.34
Cct6bPPons0.1
0.08
Cct6bPALPallidum0.14
0.13
Cct6bRHPRetrohippocampal region0.21
0.21
Cct6bsAMYStriatum-like amygdalar nuclei0.33
0.62
Cct6bSTRStriatum0.22
0.34
Cct6bSTRdStriatum dorsal region0.19
0.38
Cct6bSTRvStriatum ventral region0.25
0.22
Cct6bTHThalamus0.41
0.68
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00042123 13 105 117 QADLYISEGLHPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018