AutismKB 2.0

Annotation Detail for CCT8


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CCT8 ( C21orf112,Cctq,D21S246,KIAA0002,PRED71 )
Gene Full Name: chaperonin containing TCP1, subunit 8 (theta)
Band: 21q21.3
Quick LinksEntrez ID:10694; OMIM: NA; Uniprot ID:TCPQ_HUMAN; ENSEMBL ID: ENSG00000156261; HGNC ID: 1623
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body22 / 70761310
blastocyst21 / 62319336
fetus103 / 564012182
neonate15 / 31097482
infant69 / 236202921
juvenile65 / 555561169
adult494 / 1939121254
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma5 / 17475286
breast (mammary gland) tumor17 / 94178180
cervical tumor12 / 34366349
chondrosarcoma7 / 8282384
colorectal tumor49 / 114246428
esophageal tumor27 / 172901561
gastrointestinal tumor37 / 119369309
germ cell tumor221 / 263845837
glioma20 / 106883187
head and neck tumor27 / 136302198
kidney tumor11 / 68959159
leukemia24 / 95842250
liver tumor30 / 96359311
lung tumor48 / 103127465
lymphoma35 / 71755487
non-neoplasia37 / 97250380
normal871 / 3360307259
ovarian tumor26 / 76682339
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS162 / 1256801288
prostate cancer19 / 102680185
retinoblastoma42 / 46356906
skin tumor45 / 124949360
soft tissue/muscle tissue tumor55 / 125191439
uterine tumor20 / 90257221
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland13 / 33197391
ascites13 / 40015324
bladder17 / 29757571
blood36 / 123478291
bone14 / 71655195
bone marrow14 / 48801286
brain417 / 1100989378
cervix21 / 48171435
connective tissue27 / 149255180
ear9 / 16212555
embryonic tissue83 / 215722384
esophagus28 / 202091385
eye66 / 211054312
heart32 / 89626357
intestine105 / 234472447
kidney52 / 211777245
larynx0 / 241450 
liver59 / 207743284
lung88 / 336974261
lymph21 / 44270474
lymph node5 / 9161054
mammary gland25 / 153271163
mouth4 / 6705259
muscle17 / 107715157
nerve3 / 15768190
ovary30 / 102051293
pancreas25 / 214812116
parathyroid0 / 205390 
pharynx23 / 41328556
pituitary gland7 / 16585422
placenta75 / 280825267
prostate36 / 189345190
salivary gland8 / 20155396
skin59 / 210574280
spleen19 / 53952352
stomach26 / 96619269
testis177 / 330442535
thymus37 / 81131456
thyroid24 / 47473505
tonsil6 / 16999352
trachea11 / 52413209
umbilical cord13 / 13680950
uterus87 / 232878373
vascular17 / 51780328
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200873_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts3796.05
Adipocyte255.55
AdrenalCortex384.6
Adrenalgland149.05
Amygdala486
Appendix80.1
AtrioventricularNode63.85
BDCA4+_DentriticCells1414.7
Bonemarrow132.5
BronchialEpithelialCells1259.1
CD105+_Endothelial2063.1
CD14+_Monocytes1287.8
CD19+_BCells(neg._sel.)1258.25
CD33+_Myeloid1549.55
CD34+2074
CD4+_Tcells1457.25
CD56+_NKCells1009.9
CD71+_EarlyErythroid742.2
CD8+_Tcells1237.8
CardiacMyocytes791.05
Caudatenucleus222.5
Cerebellum44.35
CerebellumPeduncles93.6
CiliaryGanglion71.4
CingulateCortex236
Colorectaladenocarcinoma840.7
DorsalRootGanglion59.55
FetalThyroid263.25
Fetalbrain637.85
Fetalliver445.2
Fetallung554.2
GlobusPallidus166.6
Heart32.65
Hypothalamus691.2
Kidney65.9
Leukemia_chronicMyelogenousK-5622626.2
Leukemia_promyelocytic-HL-601784
Leukemialymphoblastic(MOLT-4)780.55
Liver51.55
Lung69.8
Lymphnode425.2
Lymphoma_burkitts(Daudi)2439.45
Lymphoma_burkitts(Raji)1461
MedullaOblongata183.1
OccipitalLobe299.6
OlfactoryBulb235.45
Ovary204.5
Pancreas536.15
PancreaticIslet737.9
ParietalLobe175.75
Pituitary556.55
Placenta339.9
Pons108.7
PrefrontalCortex604
Prostate297.45
Salivarygland400.3
SkeletalMuscle96.25
Skin91.45
SmoothMuscle998.85
Spinalcord240.95
SubthalamicNucleus259
SuperiorCervicalGanglion34.95
TemporalLobe166.7
Testis184.75
TestisGermCell492.15
TestisIntersitial225.75
TestisLeydigCell183.75
TestisSeminiferousTubule247.3
Thalamus298.55
Thymus210.25
Thyroid379.2
Tongue199.4
Tonsil542.45
Trachea171.6
TrigeminalGanglion32.7
Uterus309.95
UterusCorpus87.15
WholeBlood578.45
Wholebrain160.05
colon527.45
pineal_day916.28
pineal_night893.94
retina191.325
small_intestine489
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P102876
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.08 ± 0.31
Basal Forebrain10.05 ± 0.08
Basal Part of Pons10.27 ± 0.2
Cerebellar Cortex10.29 ± 0.14
Cerebellar Nuclei10.02 ± 0.25
Claustrum10.11 ± 0.3
Epithalamus9.95 ± 0.09
Frontal Lobe10.17 ± 0.24
Globus Pallidus9.42 ± 0.22
Hypothalamus10.35 ± 0.23
Insula10.29 ± 0.15
Limbic Lobe10.16 ± 0.35
Mesencephalon10.07 ± 0.36
Myelencephalon10.03 ± 0.33
Occipital Lobe9.98 ± 0.25
Parietal Lobe10.07 ± 0.27
Pontine Tegmentum10.09 ± 0.28
Striatum9.83 ± 0.26
Subthalamus10.27 ± 0.25
Temporal Lobe10.16 ± 0.29
Thalamus10 ± 0.19
White Matter9.47 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cct8CBCerebellum57.22
49.39
Cct8CTXCerebral cortex55.67
53.24
Cct8HIPHippocampal region70.21
60.94
Cct8HPFHippocampal formation68.71
60.13
Cct8HYHypothalamus59.6
55.96
Cct8LSXLateral septal complex50.19
43.89
Cct8MBMidbrain65.9
60.93
Cct8MYMedulla76.58
72.7
Cct8OLFOlfactory bulb56.74
54.09
Cct8PPons73.65
69.44
Cct8PALPallidum57.96
53.03
Cct8RHPRetrohippocampal region66.34
59.09
Cct8sAMYStriatum-like amygdalar nuclei54.69
46.88
Cct8STRStriatum51.77
25.22
Cct8STRdStriatum dorsal region37.99
17.51
Cct8STRvStriatum ventral region52.31
30.9
Cct8THThalamus57.09
53.99
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000396 14 139 152 AHEILPNLVCCSAK Peptide Atlas
TCPQ_HUMAN_0 0 0 0 AIADTGANVVVTGGK PRIDE
TCPQ_HUMAN_138 18 138 155 KAHEILPNLVCCSAKNLR PRIDE
TCPQ_HUMAN_144 12 144 155 PNLVCCSAKNLR PRIDE
TCPQ_HUMAN_155 10 155 164 DIDEVSSLLR PRIDE
TCPQ_HUMAN_181 22 181 202 LIAQACVSIFPDSGHFNVDNIR PRIDE
TCPQ_HUMAN_2 12 2 13 ALHVPKAPGFAQ PRIDE
TCPQ_HUMAN_2 13 2 14 ALHVPKAPGFAQM PRIDE
TCPQ_HUMAN_2 21 2 22 ALHVPKAPGFAQMLKEGAKHF PRIDE
TCPQ_HUMAN_206 18 206 223 ILGSGISSSSVLHGMVFK PRIDE
TCPQ_HUMAN_206 19 206 224 ILGSGISSSSVLHGMVFKK PRIDE
TCPQ_HUMAN_238 16 238 253 IAVYSCPFDGMITETK PRIDE
TCPQ_HUMAN_260 10 260 269 TAEELMNFSK PRIDE
TCPQ_HUMAN_260 21 260 280 TAEELMNFSKGEENLMDAQVK PRIDE
TCPQ_HUMAN_270 11 270 280 GEENLMDAQVK PRIDE
TCPQ_HUMAN_281 15 281 295 AIADTGANVVVTGGK PRIDE
TCPQ_HUMAN_296 11 296 306 VADMALHYANK PRIDE
TCPQ_HUMAN_296 18 296 313 VADMALHYANKYNIMLVR PRIDE
TCPQ_HUMAN_326 9 326 334 TVGATALPR PRIDE
TCPQ_HUMAN_378 12 378 389 GSTDNLMDDIER PRIDE
TCPQ_HUMAN_378 22 378 399 GSTDNLMDDIERAVDDGVNTFK PRIDE
TCPQ_HUMAN_379 11 379 389 STDNLMDDIER PRIDE
TCPQ_HUMAN_390 10 390 399 AVDDGVNTFK PRIDE
TCPQ_HUMAN_390 14 390 403 AVDDGVNTFKVLTR PRIDE
TCPQ_HUMAN_391 14 391 404 AVDDGVNTFKVLTR PRIDE
TCPQ_HUMAN_394 10 394 403 GVNTFKVLTR PRIDE
TCPQ_HUMAN_407 14 407 420 LVPGGGATEIELAK PRIDE
TCPQ_HUMAN_421 19 421 439 QITSYGETCPGLEQYAIKK PRIDE
TCPQ_HUMAN_440 10 440 449 FAEAFEAIPR PRIDE
TCPQ_HUMAN_450 16 450 465 ALAENSGVKANEVISK PRIDE
TCPQ_HUMAN_476 14 476 489 NVGLDIEAEVPAVK PRIDE
TCPQ_HUMAN_490 14 490 503 DMLEAGILDTYLGK PRIDE
TCPQ_HUMAN_490 19 490 508 DMLEAGILDTYLGKYWAIK PRIDE
TCPQ_HUMAN_509 11 509 519 LATNAAVTVLR PRIDE
TCPQ_HUMAN_520 19 520 538 VDQIIMAKPAGGPKPPSGK PRIDE
TCPQ_HUMAN_62 12 62 73 LFVTNDAATILR PRIDE
TCPQ_HUMAN_7 9 7 15 APGFAQMLK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved