AutismKB 2.0

Annotation Detail for ADCY1


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Basic Information Top
Gene Symbol:ADCY1 ( AC1 )
Gene Full Name: adenylate cyclase 1 (brain)
Band: 7p12.3
Quick LinksEntrez ID:107; OMIM: 103072; Uniprot ID:ADCY1_HUMAN; ENSEMBL ID: ENSG00000164742; HGNC ID: 232
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus92 / 564012163
neonate0 / 310970 
infant3 / 23620127
juvenile1 / 5555617
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor5 / 26384518
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal222 / 336030766
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma5 / 46356107
skin tumor8 / 12494964
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain144 / 1100989130
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye28 / 211054132
heart8 / 8962689
intestine3 / 23447212
kidney5 / 21177723
larynx0 / 241450 
liver6 / 20774328
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth2 / 6705229
muscle9 / 10771583
nerve1 / 1576863
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland1 / 2015549
skin8 / 21057437
spleen0 / 539520 
stomach0 / 966190 
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213245_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.75
Adipocyte4.95
AdrenalCortex5.5
Adrenalgland4.3
Amygdala394.45
Appendix5.35
AtrioventricularNode4
BDCA4+_DentriticCells5
Bonemarrow5.05
BronchialEpithelialCells4.75
CD105+_Endothelial4.85
CD14+_Monocytes5.15
CD19+_BCells(neg._sel.)5.05
CD33+_Myeloid6.1
CD34+6.05
CD4+_Tcells5.1
CD56+_NKCells5.75
CD71+_EarlyErythroid4.6
CD8+_Tcells4.55
CardiacMyocytes6.75
Caudatenucleus52.2
Cerebellum135.25
CerebellumPeduncles138.3
CiliaryGanglion3.75
CingulateCortex163.05
Colorectaladenocarcinoma4.95
DorsalRootGanglion3.9
FetalThyroid4.85
Fetalbrain2078.4
Fetalliver4.3
Fetallung3.95
GlobusPallidus83.45
Heart6.9
Hypothalamus25.1
Kidney4.15
Leukemia_chronicMyelogenousK-5624.45
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)3.9
Liver6.9
Lung5.35
Lymphnode4.05
Lymphoma_burkitts(Daudi)6.4
Lymphoma_burkitts(Raji)7.25
MedullaOblongata119.55
OccipitalLobe159.4
OlfactoryBulb3.9
Ovary3.4
Pancreas4.1
PancreaticIslet5.5
ParietalLobe56.15
Pituitary5.7
Placenta4.85
Pons22.05
PrefrontalCortex282.9
Prostate6.9
Salivarygland4
SkeletalMuscle6.05
Skin3.95
SmoothMuscle5.45
Spinalcord6.8
SubthalamicNucleus94.15
SuperiorCervicalGanglion6.2
TemporalLobe28.3
Testis4.2
TestisGermCell4
TestisIntersitial4.25
TestisLeydigCell4.95
TestisSeminiferousTubule4.2
Thalamus36.5
Thymus3.85
Thyroid6.35
Tongue5.05
Tonsil4.85
Trachea4.1
TrigeminalGanglion6.1
Uterus4.05
UterusCorpus4.55
WholeBlood5.3
Wholebrain252.05
colon5
pineal_day198.28
pineal_night147.22
retina67.8
small_intestine4.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_59_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.55 ± 0.55
Basal Forebrain4.02 ± 0.49
Basal Part of Pons4.48 ± 0.44
Cerebellar Cortex4.42 ± 0.42
Cerebellar Nuclei4 ± 0.65
Claustrum4.64 ± 0.6
Epithalamus3.54 ± 0.67
Frontal Lobe4.33 ± 0.59
Globus Pallidus3.04 ± 0.25
Hypothalamus3.82 ± 0.4
Insula4.2 ± 0.4
Limbic Lobe4.55 ± 0.56
Mesencephalon4.23 ± 0.67
Myelencephalon4.31 ± 0.59
Occipital Lobe4.74 ± 0.55
Parietal Lobe4.43 ± 0.49
Pontine Tegmentum4.15 ± 0.62
Striatum4.19 ± 0.66
Subthalamus3.59 ± 0.46
Temporal Lobe4.31 ± 0.46
Thalamus4.33 ± 0.6
White Matter2.69 ± 0.34
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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