AutismKB 2.0

Annotation Detail for YME1L1


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Basic Information Top
Gene Symbol:YME1L1 ( FTSH,MEG4,PAMP,YME1L )
Gene Full Name: YME1-like 1 (S. cerevisiae)
Band: 10p12.1
Quick LinksEntrez ID:10730; OMIM: 607472; Uniprot ID:YMEL1_HUMAN; ENSEMBL ID: ENSG00000136758; HGNC ID: 12843
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst16 / 62319256
fetus87 / 564012154
neonate12 / 31097385
infant1 / 2362042
juvenile17 / 55556305
adult301 / 1939121155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor18 / 94178191
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor2 / 11424617
esophageal tumor3 / 17290173
gastrointestinal tumor18 / 119369150
germ cell tumor102 / 263845386
glioma3 / 10688328
head and neck tumor44 / 136302322
kidney tumor6 / 6895987
leukemia21 / 95842219
liver tumor11 / 96359114
lung tumor3 / 10312729
lymphoma7 / 7175597
non-neoplasia25 / 97250257
normal575 / 3360307171
ovarian tumor5 / 7668265
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS20 / 125680159
prostate cancer8 / 10268077
retinoblastoma15 / 46356323
skin tumor17 / 124949136
soft tissue/muscle tissue tumor24 / 125191191
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland6 / 33197180
ascites6 / 40015149
bladder1 / 2975733
blood32 / 123478259
bone6 / 7165583
bone marrow5 / 48801102
brain194 / 1100989176
cervix1 / 4817120
connective tissue42 / 149255281
ear0 / 162120 
embryonic tissue48 / 215722222
esophagus5 / 20209247
eye23 / 211054108
heart7 / 8962678
intestine15 / 23447263
kidney34 / 211777160
larynx8 / 24145331
liver26 / 207743125
lung25 / 33697474
lymph4 / 4427090
lymph node22 / 91610240
mammary gland23 / 153271150
mouth44 / 67052656
muscle36 / 107715334
nerve1 / 1576863
ovary5 / 10205148
pancreas19 / 21481288
parathyroid2 / 2053997
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta40 / 280825142
prostate18 / 18934595
salivary gland3 / 20155148
skin41 / 210574194
spleen12 / 53952222
stomach10 / 96619103
testis132 / 330442399
thymus32 / 81131394
thyroid2 / 4747342
tonsil1 / 1699958
trachea30 / 52413572
umbilical cord0 / 136800 
uterus50 / 232878214
vascular14 / 51780270
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201352_at
Cell line Expression level Expression bar
721_B_lymphoblasts517.75
Adipocyte169.6
AdrenalCortex151.65
Adrenalgland122.85
Amygdala348.65
Appendix111.75
AtrioventricularNode61
BDCA4+_DentriticCells731.9
Bonemarrow89.95
BronchialEpithelialCells313.9
CD105+_Endothelial407.65
CD14+_Monocytes409.7
CD19+_BCells(neg._sel.)863.7
CD33+_Myeloid515.1
CD34+564.25
CD4+_Tcells431.6
CD56+_NKCells694.95
CD71+_EarlyErythroid228
CD8+_Tcells606.45
CardiacMyocytes169
Caudatenucleus120.35
Cerebellum48.4
CerebellumPeduncles83.4
CiliaryGanglion40.75
CingulateCortex119.65
Colorectaladenocarcinoma320.8
DorsalRootGanglion79.65
FetalThyroid171.55
Fetalbrain128.85
Fetalliver177.55
Fetallung188.55
GlobusPallidus66.05
Heart19.5
Hypothalamus251.75
Kidney59.55
Leukemia_chronicMyelogenousK-562254.05
Leukemia_promyelocytic-HL-60168.55
Leukemialymphoblastic(MOLT-4)194.05
Liver38.9
Lung44.3
Lymphnode153.1
Lymphoma_burkitts(Daudi)209.15
Lymphoma_burkitts(Raji)265.9
MedullaOblongata113.45
OccipitalLobe140.3
OlfactoryBulb115.2
Ovary103.75
Pancreas131.2
PancreaticIslet255.55
ParietalLobe67.15
Pituitary298.8
Placenta145.05
Pons85.35
PrefrontalCortex204.5
Prostate279.15
Salivarygland134.15
SkeletalMuscle149.4
Skin66.8
SmoothMuscle289.3
Spinalcord150.4
SubthalamicNucleus97.2
SuperiorCervicalGanglion129.35
TemporalLobe66.4
Testis61.05
TestisGermCell221.05
TestisIntersitial89.05
TestisLeydigCell91.05
TestisSeminiferousTubule96.65
Thalamus109.05
Thymus108.45
Thyroid547.25
Tongue124.65
Tonsil137.9
Trachea160
TrigeminalGanglion144.25
Uterus230
UterusCorpus104.35
WholeBlood522
Wholebrain108.5
colon391.9
pineal_day620.28
pineal_night834.36
retina302.15
small_intestine268.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P104201
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.4 ± 0.27
Basal Forebrain8.41 ± 0.09
Basal Part of Pons8.74 ± 0.22
Cerebellar Cortex8.72 ± 0.17
Cerebellar Nuclei8.65 ± 0.23
Claustrum8.55 ± 0.33
Epithalamus8.67 ± 0.19
Frontal Lobe8.73 ± 0.2
Globus Pallidus8.3 ± 0.17
Hypothalamus8.94 ± 0.24
Insula8.71 ± 0.22
Limbic Lobe8.51 ± 0.35
Mesencephalon8.65 ± 0.33
Myelencephalon8.52 ± 0.32
Occipital Lobe8.4 ± 0.32
Parietal Lobe8.64 ± 0.23
Pontine Tegmentum8.58 ± 0.3
Striatum8.21 ± 0.23
Subthalamus8.97 ± 0.19
Temporal Lobe8.64 ± 0.3
Thalamus8.5 ± 0.28
White Matter8.39 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Yme1l1CBCerebellum27.26
33.66
Yme1l1CTXCerebral cortex85.98
73
Yme1l1HIPHippocampal region71.97
100
Yme1l1HPFHippocampal formation83.06
100
Yme1l1HYHypothalamus56.92
49.86
Yme1l1LSXLateral septal complex44.19
36.05
Yme1l1MBMidbrain25.64
26.04
Yme1l1MYMedulla20.4
25.43
Yme1l1OLFOlfactory bulb64.11
62.57
Yme1l1PPons23.03
27.07
Yme1l1PALPallidum41.92
39.99
Yme1l1RHPRetrohippocampal region100
98.92
Yme1l1sAMYStriatum-like amygdalar nuclei64.12
53.89
Yme1l1STRStriatum43.27
34.83
Yme1l1STRdStriatum dorsal region40.31
31.91
Yme1l1STRvStriatum ventral region45.58
36.72
Yme1l1THThalamus42.67
37.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000599 18 429 446 ANAPCVIFIDELDSVGGK Peptide Atlas
YMEL1_HUMAN_498 13 498 510 FDMQVTVPRPDVK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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