AutismKB 2.0

Annotation Detail for TCFL5


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Basic Information Top
Gene Symbol:TCFL5 ( CHA,E2BP-1,Figlb,MGC46135,bHLHe82 )
Gene Full Name: transcription factor-like 5 (basic helix-loop-helix)
Band: 20q13.33
Quick LinksEntrez ID:10732; OMIM: 604745; Uniprot ID:TCFL5_HUMAN; ENSEMBL ID: ENSG00000101190; HGNC ID: 11646
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus4 / 5640127
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult32 / 193912116
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia4 / 9584241
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia4 / 9725041
normal45 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain15 / 110098913
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart1 / 8962611
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph1 / 4427022
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate3 / 18934515
salivary gland1 / 2015549
skin16 / 21057475
spleen0 / 539520 
stomach2 / 9661920
testis12 / 33044236
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204849_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.85
Adipocyte9
AdrenalCortex5.5
Adrenalgland4.95
Amygdala50.25
Appendix6
AtrioventricularNode4.9
BDCA4+_DentriticCells6.5
Bonemarrow5.35
BronchialEpithelialCells6.95
CD105+_Endothelial5.95
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)7.95
CD33+_Myeloid7.95
CD34+11.4
CD4+_Tcells6.05
CD56+_NKCells8.25
CD71+_EarlyErythroid4.85
CD8+_Tcells6.2
CardiacMyocytes7.25
Caudatenucleus12.8
Cerebellum4.75
CerebellumPeduncles7.2
CiliaryGanglion4.1
CingulateCortex29.4
Colorectaladenocarcinoma13.5
DorsalRootGanglion4.6
FetalThyroid5.7
Fetalbrain5.95
Fetalliver5.05
Fetallung4.5
GlobusPallidus5.25
Heart7.45
Hypothalamus31.5
Kidney4.75
Leukemia_chronicMyelogenousK-5625.1
Leukemia_promyelocytic-HL-6011.95
Leukemialymphoblastic(MOLT-4)118.25
Liver7.7
Lung6.7
Lymphnode5.15
Lymphoma_burkitts(Daudi)7.5
Lymphoma_burkitts(Raji)8.9
MedullaOblongata20.05
OccipitalLobe20.9
OlfactoryBulb5
Ovary3.85
Pancreas4.75
PancreaticIslet5.8
ParietalLobe11.7
Pituitary6.9
Placenta5.7
Pons6.4
PrefrontalCortex79
Prostate8.4
Salivarygland4.65
SkeletalMuscle6.75
Skin4.05
SmoothMuscle7.15
Spinalcord94.85
SubthalamicNucleus7.05
SuperiorCervicalGanglion6.6
TemporalLobe10.6
Testis531.8
TestisGermCell497.8
TestisIntersitial882.9
TestisLeydigCell427.6
TestisSeminiferousTubule417.9
Thalamus11.3
Thymus11.9
Thyroid67.95
Tongue5.1
Tonsil5.15
Trachea5.2
TrigeminalGanglion5.8
Uterus7.1
UterusCorpus5.2
WholeBlood8.1
Wholebrain40.8
colon8.35
pineal_day15.62
pineal_night18.96
retina47.575
small_intestine6.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1538_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.51 ± 0.62
Basal Forebrain4.87 ± 0.83
Basal Part of Pons4.69 ± 0.43
Cerebellar Cortex4.16 ± 0.4
Cerebellar Nuclei5.17 ± 0.73
Claustrum4.77 ± 0.65
Epithalamus4.5 ± 0.53
Frontal Lobe4.41 ± 0.67
Globus Pallidus6.11 ± 0.33
Hypothalamus4.27 ± 0.43
Insula4.07 ± 0.42
Limbic Lobe4.36 ± 0.7
Mesencephalon4.74 ± 0.64
Myelencephalon4.66 ± 0.6
Occipital Lobe4.72 ± 0.56
Parietal Lobe4.52 ± 0.47
Pontine Tegmentum4.56 ± 0.57
Striatum4.97 ± 0.53
Subthalamus4.23 ± 0.6
Temporal Lobe4.44 ± 0.52
Thalamus4.82 ± 0.49
White Matter6.39 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tcfl5CBCerebellum8.44
9.28
Tcfl5CTXCerebral cortex1.98
2.02
Tcfl5HIPHippocampal region1.22
1.5
Tcfl5HPFHippocampal formation1.22
1.38
Tcfl5HYHypothalamus0.17
0.12
Tcfl5LSXLateral septal complex0.08
0.07
Tcfl5MBMidbrain1.35
1.57
Tcfl5MYMedulla6.55
6.92
Tcfl5OLFOlfactory bulb5.77
5.96
Tcfl5PPons0.98
1.31
Tcfl5PALPallidum0.21
0.15
Tcfl5RHPRetrohippocampal region1.25
1.23
Tcfl5sAMYStriatum-like amygdalar nuclei0.36
0.34
Tcfl5STRStriatum0.29
0.35
Tcfl5STRdStriatum dorsal region0.18
0.32
Tcfl5STRvStriatum ventral region0.61
0.51
Tcfl5THThalamus0.28
0.32
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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