AutismKB 2.0

Annotation Detail for RAI1


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Basic Information Top
Gene Symbol:RAI1 ( DKFZp434A139,KIAA1820,MGC12824,SMCR,SMS )
Gene Full Name: retinoic acid induced 1
Band: 17p11.2
Quick LinksEntrez ID:10743; OMIM: 607642; Uniprot ID:RAI1_HUMAN; ENSEMBL ID: ENSG00000108557; HGNC ID: 9834
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor14 / 114246122
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal64 / 336030719
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain9 / 11009898
cervix3 / 4817162
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye13 / 21105461
heart2 / 8962622
intestine18 / 23447276
kidney2 / 2117779
larynx2 / 2414582
liver2 / 2077439
lung6 / 33697417
lymph1 / 4427022
lymph node1 / 9161010
mammary gland2 / 15327113
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary1 / 1020519
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach6 / 9661962
testis0 / 3304420 
thymus1 / 8113112
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P77807
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.91 ± 0.58
Basal Forebrain7.47 ± 0.14
Basal Part of Pons7.27 ± 0.42
Cerebellar Cortex6.92 ± 0.36
Cerebellar Nuclei6.99 ± 0.39
Claustrum7.94 ± 0.63
Epithalamus6.62 ± 0.36
Frontal Lobe7.04 ± 0.44
Globus Pallidus7.06 ± 0.21
Hypothalamus7.03 ± 0.47
Insula7.1 ± 0.41
Limbic Lobe7.53 ± 0.5
Mesencephalon7.36 ± 0.5
Myelencephalon7.34 ± 0.51
Occipital Lobe7.75 ± 0.56
Parietal Lobe7.4 ± 0.42
Pontine Tegmentum7.06 ± 0.42
Striatum7.62 ± 0.46
Subthalamus7 ± 0.4
Temporal Lobe7.25 ± 0.42
Thalamus7.11 ± 0.38
White Matter7.01 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rai1CBCerebellum17.96
19.15
Rai1CTXCerebral cortex52.6
37.42
Rai1HIPHippocampal region36.39
41.8
Rai1HPFHippocampal formation36.24
35.59
Rai1HYHypothalamus8.69
6.28
Rai1LSXLateral septal complex20.37
13.1
Rai1MBMidbrain14.24
12.3
Rai1MYMedulla18.23
17.05
Rai1OLFOlfactory bulb42.2
31.58
Rai1PPons13.6
12.89
Rai1PALPallidum13.06
10.28
Rai1RHPRetrohippocampal region36.16
26.01
Rai1sAMYStriatum-like amygdalar nuclei19.14
12.8
Rai1STRStriatum31.21
20.2
Rai1STRdStriatum dorsal region34.06
22.07
Rai1STRvStriatum ventral region36.35
22.81
Rai1THThalamus17.92
14.01
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007005 25 238 262 SCTAPTAQPHDRPLTASSSLAPGQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018