AutismKB 2.0

Annotation Detail for KIF1C


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Basic Information Top
Gene Symbol:KIF1C ( KIAA0706,LTXS1 )
Gene Full Name: kinesin family member 1C
Band: 17p13.2
Quick LinksEntrez ID:10749; OMIM: 603060; Uniprot ID:KIF1C_HUMAN; ENSEMBL ID: ENSG00000129250; HGNC ID: 6317
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult180 / 193912192
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor16 / 94178169
cervical tumor4 / 34366116
chondrosarcoma14 / 82823169
colorectal tumor30 / 114246262
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor15 / 26384556
glioma19 / 106883177
head and neck tumor25 / 136302183
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor6 / 9635962
lung tumor9 / 10312787
lymphoma2 / 7175527
non-neoplasia15 / 97250154
normal122 / 336030736
ovarian tumor2 / 7668226
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer14 / 102680136
retinoblastoma5 / 46356107
skin tumor36 / 124949288
soft tissue/muscle tissue tumor14 / 125191111
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites4 / 4001599
bladder3 / 29757100
blood2 / 12347816
bone13 / 71655181
bone marrow0 / 488010 
brain42 / 110098938
cervix4 / 4817183
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye15 / 21105471
heart3 / 8962633
intestine46 / 234472196
kidney12 / 21177756
larynx3 / 24145124
liver6 / 20774328
lung28 / 33697483
lymph2 / 4427045
lymph node3 / 9161032
mammary gland24 / 153271156
mouth8 / 67052119
muscle15 / 107715139
nerve0 / 157680 
ovary10 / 10205197
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland0 / 165850 
placenta5 / 28082517
prostate17 / 18934589
salivary gland6 / 20155297
skin41 / 210574194
spleen1 / 5395218
stomach11 / 96619113
testis3 / 3304429
thymus0 / 811310 
thyroid13 / 47473273
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus28 / 232878120
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209245_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.25
Adipocyte8.75
AdrenalCortex14.55
Adrenalgland8.4
Amygdala8.95
Appendix11.25
AtrioventricularNode10.3
BDCA4+_DentriticCells8.55
Bonemarrow10.3
BronchialEpithelialCells8.25
CD105+_Endothelial8.7
CD14+_Monocytes9.55
CD19+_BCells(neg._sel.)8.95
CD33+_Myeloid10.7
CD34+10.65
CD4+_Tcells8.8
CD56+_NKCells9.3
CD71+_EarlyErythroid8.6
CD8+_Tcells7.6
CardiacMyocytes12.3
Caudatenucleus8.1
Cerebellum7.35
CerebellumPeduncles11.25
CiliaryGanglion8.65
CingulateCortex14.05
Colorectaladenocarcinoma8.65
DorsalRootGanglion7.9
FetalThyroid8.95
Fetalbrain8.6
Fetalliver8
Fetallung6.45
GlobusPallidus7.7
Heart16.2
Hypothalamus9.65
Kidney8.75
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-607.8
Leukemialymphoblastic(MOLT-4)6.8
Liver14.55
Lung9.4
Lymphnode7.2
Lymphoma_burkitts(Daudi)12.9
Lymphoma_burkitts(Raji)14.05
MedullaOblongata8.05
OccipitalLobe8.15
OlfactoryBulb6.85
Ovary6.7
Pancreas7.2
PancreaticIslet9.8
ParietalLobe11.3
Pituitary10.65
Placenta8.5
Pons9.05
PrefrontalCortex10.5
Prostate10.2
Salivarygland7.85
SkeletalMuscle14.8
Skin8
SmoothMuscle9.95
Spinalcord11.45
SubthalamicNucleus10.5
SuperiorCervicalGanglion17.2
TemporalLobe8.55
Testis7.5
TestisGermCell7.2
TestisIntersitial7.75
TestisLeydigCell9.85
TestisSeminiferousTubule7.7
Thalamus9.65
Thymus6.5
Thyroid10.55
Tongue11
Tonsil9.1
Trachea7.3
TrigeminalGanglion12.65
Uterus6.8
UterusCorpus9.95
WholeBlood9.25
Wholebrain6.9
colon9
pineal_day10.42
pineal_night10.3
retina10.95
small_intestine8.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_275_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.7 ± 0.81
Basal Forebrain4.24 ± 0.75
Basal Part of Pons3.93 ± 0.92
Cerebellar Cortex3.6 ± 0.46
Cerebellar Nuclei4.29 ± 0.59
Claustrum4.12 ± 0.79
Epithalamus4.03 ± 0.72
Frontal Lobe3.69 ± 0.78
Globus Pallidus5.78 ± 0.34
Hypothalamus3.36 ± 0.82
Insula3.42 ± 0.59
Limbic Lobe3.58 ± 0.71
Mesencephalon4.16 ± 0.84
Myelencephalon4.06 ± 0.73
Occipital Lobe4.2 ± 0.65
Parietal Lobe4 ± 0.55
Pontine Tegmentum3.78 ± 0.69
Striatum4.52 ± 0.71
Subthalamus4.15 ± 0.29
Temporal Lobe3.88 ± 0.6
Thalamus4.2 ± 0.66
White Matter5.7 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kif1cCBCerebellum10.78
12.74
Kif1cCTXCerebral cortex34.63
23.23
Kif1cHIPHippocampal region41.48
49.88
Kif1cHPFHippocampal formation32.93
34.37
Kif1cHYHypothalamus1.77
1.56
Kif1cLSXLateral septal complex4.48
5.04
Kif1cMBMidbrain6.62
5.99
Kif1cMYMedulla10.57
11.15
Kif1cOLFOlfactory bulb20.36
14.88
Kif1cPPons9.64
9.19
Kif1cPALPallidum2.24
1.9
Kif1cRHPRetrohippocampal region20.13
14.9
Kif1csAMYStriatum-like amygdalar nuclei2.1
3.98
Kif1cSTRStriatum3.06
2.91
Kif1cSTRdStriatum dorsal region3.19
2.9
Kif1cSTRvStriatum ventral region2.39
1.53
Kif1cTHThalamus13.46
11.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00496841 37 871 907 VIPLAQDHEDENEEGGEVPWAPPEGSEAAEEAAPSDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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