AutismKB 2.0

Annotation Detail for KDM5B


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Basic Information Top
Gene Symbol:KDM5B ( CT31,FLJ10538,FLJ12459,FLJ12491,FLJ16281,FLJ23670,JARID1B,PLU-1,PLU1,PUT1,RBBP2H1A )
Gene Full Name: lysine (K)-specific demethylase 5B
Band: 1q32.1
Quick LinksEntrez ID:10765; OMIM: 605393; Uniprot ID:KDM5B_HUMAN; ENSEMBL ID: ENSG00000117139; HGNC ID: 18039
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst19 / 62319304
fetus116 / 564012205
neonate1 / 3109732
infant0 / 236200 
juvenile4 / 5555671
adult200 / 1939121103
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor12 / 94178127
cervical tumor2 / 3436658
chondrosarcoma4 / 8282348
colorectal tumor13 / 114246113
esophageal tumor4 / 17290231
gastrointestinal tumor5 / 11936941
germ cell tumor76 / 263845288
glioma1 / 1068839
head and neck tumor36 / 136302264
kidney tumor1 / 6895914
leukemia11 / 95842114
liver tumor13 / 96359134
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal351 / 3360307104
ovarian tumor4 / 7668252
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor7 / 12494956
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder0 / 297570 
blood6 / 12347848
bone4 / 7165555
bone marrow1 / 4880120
brain107 / 110098997
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue43 / 215722199
esophagus4 / 20209197
eye27 / 211054127
heart15 / 89626167
intestine20 / 23447285
kidney19 / 21177789
larynx0 / 241450 
liver16 / 20774377
lung31 / 33697491
lymph0 / 442700 
lymph node1 / 9161010
mammary gland21 / 153271137
mouth32 / 67052477
muscle4 / 10771537
nerve0 / 157680 
ovary4 / 10205139
pancreas2 / 2148129
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland2 / 16585120
placenta23 / 28082581
prostate12 / 18934563
salivary gland1 / 2015549
skin12 / 21057456
spleen0 / 539520 
stomach1 / 9661910
testis156 / 330442472
thymus13 / 81131160
thyroid4 / 4747384
tonsil0 / 169990 
trachea14 / 52413267
umbilical cord3 / 13680219
uterus24 / 232878103
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201548_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.25
Adipocyte11.4
AdrenalCortex11.4
Adrenalgland8.8
Amygdala11.25
Appendix10.65
AtrioventricularNode8
BDCA4+_DentriticCells11.4
Bonemarrow10.15
BronchialEpithelialCells75.95
CD105+_Endothelial13.25
CD14+_Monocytes8.65
CD19+_BCells(neg._sel.)11.15
CD33+_Myeloid14.45
CD34+68.8
CD4+_Tcells15.1
CD56+_NKCells11
CD71+_EarlyErythroid11.95
CD8+_Tcells6.9
CardiacMyocytes14.3
Caudatenucleus8.2
Cerebellum8.9
CerebellumPeduncles11.8
CiliaryGanglion7.35
CingulateCortex10.65
Colorectaladenocarcinoma8.55
DorsalRootGanglion7.85
FetalThyroid9.35
Fetalbrain38
Fetalliver9.9
Fetallung22.5
GlobusPallidus6.05
Heart13.2
Hypothalamus11.4
Kidney8.45
Leukemia_chronicMyelogenousK-56254.8
Leukemia_promyelocytic-HL-608.35
Leukemialymphoblastic(MOLT-4)18.5
Liver12.15
Lung10.9
Lymphnode10
Lymphoma_burkitts(Daudi)13.3
Lymphoma_burkitts(Raji)12.2
MedullaOblongata11.55
OccipitalLobe12.85
OlfactoryBulb6.4
Ovary6.9
Pancreas9.25
PancreaticIslet11.55
ParietalLobe11.05
Pituitary15.1
Placenta83.15
Pons10.6
PrefrontalCortex12.7
Prostate14.9
Salivarygland8
SkeletalMuscle12.8
Skin8.05
SmoothMuscle45.15
Spinalcord8.85
SubthalamicNucleus8.25
SuperiorCervicalGanglion13.8
TemporalLobe9.45
Testis323.8
TestisGermCell269.35
TestisIntersitial357.8
TestisLeydigCell263.4
TestisSeminiferousTubule286.1
Thalamus7.7
Thymus25.65
Thyroid13.35
Tongue10.3
Tonsil9.2
Trachea16.35
TrigeminalGanglion10.5
Uterus11.15
UterusCorpus11.3
WholeBlood15.1
Wholebrain11.75
colon12.2
pineal_day142.6
pineal_night141.7
retina45.575
small_intestine10.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P1038
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.36 ± 0.49
Basal Forebrain6.63 ± 0.2
Basal Part of Pons6.2 ± 0.43
Cerebellar Cortex6.48 ± 0.28
Cerebellar Nuclei5.85 ± 0.36
Claustrum6.29 ± 0.44
Epithalamus6.59 ± 0.4
Frontal Lobe6.24 ± 0.36
Globus Pallidus5.36 ± 0.27
Hypothalamus6.3 ± 0.32
Insula6.42 ± 0.38
Limbic Lobe6.49 ± 0.45
Mesencephalon6.36 ± 0.43
Myelencephalon6.33 ± 0.42
Occipital Lobe6.7 ± 0.33
Parietal Lobe6.4 ± 0.35
Pontine Tegmentum6.33 ± 0.4
Striatum6.7 ± 0.38
Subthalamus5.96 ± 0.41
Temporal Lobe6.4 ± 0.34
Thalamus6.22 ± 0.38
White Matter5.98 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Jarid1bCBCerebellum19.5
19.44
Jarid1bCTXCerebral cortex66.45
47.59
Jarid1bHIPHippocampal region43.87
78.64
Jarid1bHPFHippocampal formation42.04
59.08
Jarid1bHYHypothalamus17.1
11.96
Jarid1bLSXLateral septal complex51.55
34.84
Jarid1bMBMidbrain18.62
14.2
Jarid1bMYMedulla12.08
11.18
Jarid1bOLFOlfactory bulb74.48
63.79
Jarid1bPPons15.84
13.51
Jarid1bPALPallidum19.81
14.47
Jarid1bRHPRetrohippocampal region39.03
31.19
Jarid1bsAMYStriatum-like amygdalar nuclei41.63
27.53
Jarid1bSTRStriatum49.07
33.89
Jarid1bSTRdStriatum dorsal region44.39
30.43
Jarid1bSTRvStriatum ventral region66.84
45.95
Jarid1bTHThalamus27.4
21.81
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00080798 13 1033 1045 VPVLDTLIELVTR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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