AutismKB 2.0

Annotation Detail for POP4


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Basic Information Top
Gene Symbol:POP4 ( RPP29 )
Gene Full Name: processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
Band: 19q12
Quick LinksEntrez ID:10775; OMIM: 606114; Uniprot ID:RPP29_HUMAN; ENSEMBL ID: ENSG00000105171; HGNC ID: 30081
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus37 / 56401265
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult118 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma9 / 82823108
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor7 / 26384526
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor11 / 96359114
lung tumor13 / 103127126
lymphoma10 / 71755139
non-neoplasia5 / 9725051
normal187 / 336030755
ovarian tumor28 / 76682365
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites8 / 40015199
bladder2 / 2975767
blood17 / 123478137
bone6 / 7165583
bone marrow5 / 48801102
brain61 / 110098955
cervix2 / 4817141
connective tissue4 / 14925526
ear1 / 1621261
embryonic tissue6 / 21572227
esophagus1 / 2020949
eye12 / 21105456
heart7 / 8962678
intestine12 / 23447251
kidney10 / 21177747
larynx0 / 241450 
liver16 / 20774377
lung36 / 336974106
lymph7 / 44270158
lymph node5 / 9161054
mammary gland9 / 15327158
mouth1 / 6705214
muscle1 / 1077159
nerve2 / 15768126
ovary29 / 102051284
pancreas9 / 21481241
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta9 / 28082532
prostate3 / 18934515
salivary gland0 / 201550 
skin5 / 21057423
spleen4 / 5395274
stomach1 / 9661910
testis22 / 33044266
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus17 / 23287872
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202868_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts119.2
Adipocyte24.6
AdrenalCortex7.95
Adrenalgland7.3
Amygdala28.45
Appendix7.55
AtrioventricularNode6
BDCA4+_DentriticCells149.3
Bonemarrow7.6
BronchialEpithelialCells109.7
CD105+_Endothelial30
CD14+_Monocytes97.4
CD19+_BCells(neg._sel.)66.1
CD33+_Myeloid87.85
CD34+55.3
CD4+_Tcells35.8
CD56+_NKCells106.1
CD71+_EarlyErythroid16.9
CD8+_Tcells45.4
CardiacMyocytes10.1
Caudatenucleus7.55
Cerebellum6.2
CerebellumPeduncles8.6
CiliaryGanglion5.4
CingulateCortex7.4
Colorectaladenocarcinoma12.75
DorsalRootGanglion6.35
FetalThyroid9.85
Fetalbrain7.75
Fetalliver7.4
Fetallung8.15
GlobusPallidus5.65
Heart9.65
Hypothalamus18.5
Kidney12.7
Leukemia_chronicMyelogenousK-56211.3
Leukemia_promyelocytic-HL-6011.6
Leukemialymphoblastic(MOLT-4)24.65
Liver10.3
Lung42.25
Lymphnode6.3
Lymphoma_burkitts(Daudi)29.3
Lymphoma_burkitts(Raji)11.4
MedullaOblongata8.95
OccipitalLobe10.1
OlfactoryBulb6.55
Ovary5.35
Pancreas7.85
PancreaticIslet11.4
ParietalLobe8.05
Pituitary10.5
Placenta10.75
Pons7.3
PrefrontalCortex10.15
Prostate26.65
Salivarygland7.85
SkeletalMuscle13.1
Skin6.7
SmoothMuscle32.95
Spinalcord8.25
SubthalamicNucleus7
SuperiorCervicalGanglion9.55
TemporalLobe7.05
Testis62.7
TestisGermCell19.5
TestisIntersitial44.1
TestisLeydigCell12.35
TestisSeminiferousTubule14.5
Thalamus11.85
Thymus18.1
Thyroid54.7
Tongue8.75
Tonsil14.5
Trachea8.1
TrigeminalGanglion7
Uterus6.55
UterusCorpus6.8
WholeBlood29.7
Wholebrain12.4
colon28.05
pineal_day28.14
pineal_night50.72
retina12.725
small_intestine21.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P90533
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.13 ± 0.36
Basal Forebrain8.11 ± 0.24
Basal Part of Pons8.65 ± 0.15
Cerebellar Cortex8.14 ± 0.23
Cerebellar Nuclei8.58 ± 0.25
Claustrum8.13 ± 0.46
Epithalamus8.32 ± 0.24
Frontal Lobe8.53 ± 0.28
Globus Pallidus7.99 ± 0.49
Hypothalamus8.54 ± 0.18
Insula8.51 ± 0.2
Limbic Lobe8.21 ± 0.52
Mesencephalon8.23 ± 0.35
Myelencephalon8.25 ± 0.44
Occipital Lobe7.91 ± 0.46
Parietal Lobe8.3 ± 0.4
Pontine Tegmentum8.35 ± 0.37
Striatum8.09 ± 0.4
Subthalamus8.65 ± 0.34
Temporal Lobe8.49 ± 0.36
Thalamus8.26 ± 0.3
White Matter7.87 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pop4CBCerebellum23.71
36.35
Pop4CTXCerebral cortex72.63
58.13
Pop4HIPHippocampal region42.31
58.19
Pop4HPFHippocampal formation52.88
61.15
Pop4HYHypothalamus11.57
9.75
Pop4LSXLateral septal complex31.19
25.72
Pop4MBMidbrain25.51
24.26
Pop4MYMedulla42.56
50.93
Pop4OLFOlfactory bulb68.77
58.32
Pop4PPons30.58
34.3
Pop4PALPallidum24.21
22.42
Pop4RHPRetrohippocampal region68.82
65.21
Pop4sAMYStriatum-like amygdalar nuclei30.64
24.83
Pop4STRStriatum32.54
25.27
Pop4STRdStriatum dorsal region30.73
24.01
Pop4STRvStriatum ventral region39.53
28.35
Pop4THThalamus41.05
38.81
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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