Annotation Detail for NEK6
Basic Information Top
| Gene Symbol: | NEK6 ( SID6-1512 ) |
|---|---|
| Gene Full Name: | NIMA (never in mitosis gene a)-related kinase 6 |
| Band: | 9q33.3 |
| Quick Links | Entrez ID:10783; OMIM: 604884; Uniprot ID:NEK6_HUMAN; ENSEMBL ID: ENSG00000119408; HGNC ID: 7749 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.197071
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 38 / 564012 | 67 |  |
| neonate | 7 / 31097 | 225 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 128 / 1939121 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 10 / 82823 | 120 | |
| colorectal tumor | 10 / 114246 | 87 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 12 / 119369 | 100 | |
| germ cell tumor | 7 / 263845 | 26 | |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 9 / 68959 | 130 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 6 / 96359 | 62 | |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 5 / 71755 | 69 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 195 / 3360307 | 58 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 10 / 104616 | 95 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 7 / 102680 | 68 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 7 / 124949 | 56 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 |  |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 7 / 40015 | 174 | |
| bladder | 0 / 29757 | 0 | |
| blood | 14 / 123478 | 113 | |
| bone | 10 / 71655 | 139 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 32 / 1100989 | 29 | |
| cervix | 4 / 48171 | 83 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 3 / 89626 | 33 | |
| intestine | 15 / 234472 | 63 | |
| kidney | 21 / 211777 | 99 | |
| larynx | 0 / 24145 | 0 | |
| liver | 12 / 207743 | 57 | |
| lung | 22 / 336974 | 65 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 15 / 91610 | 163 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 24 / 280825 | 85 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 12 / 210574 | 56 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 6 / 96619 | 62 | |
| testis | 8 / 330442 | 24 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 4 / 16999 | 235 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 3 / 13680 | 219 | |
| uterus | 11 / 232878 | 47 | |
| vascular | 3 / 51780 | 57 | |
Microarray in - Probe name: A_23_P216920
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.94 ± 0.28 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.99 ± 0.29 | |
| Basal Part of Pons | 7.19 ± 0.3 | |
| Cerebellar Cortex | 7.38 ± 0.18 | |
| Cerebellar Nuclei | 7.3 ± 0.24 | |
| Claustrum | 7.58 ± 0.34 | |
| Epithalamus | 7.65 ± 0.24 | |
| Frontal Lobe | 7.68 ± 0.31 | |
| Globus Pallidus | 8.43 ± 0.24 | |
| Hypothalamus | 7.78 ± 0.23 | |
| Insula | 7.73 ± 0.25 | |
| Limbic Lobe | 7.75 ± 0.31 | |
| Mesencephalon | 7.94 ± 0.45 | |
| Myelencephalon | 7.81 ± 0.39 | |
| Occipital Lobe | 7.95 ± 0.35 | |
| Parietal Lobe | 7.8 ± 0.32 | |
| Pontine Tegmentum | 7.84 ± 0.2 | |
| Striatum | 8.21 ± 0.22 | |
| Subthalamus | 7.72 ± 0.25 | |
| Temporal Lobe | 7.79 ± 0.26 | |
| Thalamus | 7.84 ± 0.3 | |
| White Matter | 6.54 ± 0.36 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nek6 | CB | Cerebellum | 0 | |
| 0 | | |||
| Nek6 | CTX | Cerebral cortex | 0 | |
| 0 | | |||
| Nek6 | HIP | Hippocampal region | 0 | |
| 0 | | |||
| Nek6 | HPF | Hippocampal formation | 0 | |
| 0 | | |||
| Nek6 | HY | Hypothalamus | 0 | |
| 0 | | |||
| Nek6 | LSX | Lateral septal complex | 0 | |
| 0 | | |||
| Nek6 | MB | Midbrain | 0 | |
| 0 | | |||
| Nek6 | MY | Medulla | 0 | |
| 0 | | |||
| Nek6 | OLF | Olfactory bulb | 0 | |
| 0 | | |||
| Nek6 | P | Pons | 0 | |
| 0 | | |||
| Nek6 | PAL | Pallidum | 0 | |
| 0 | | |||
| Nek6 | RHP | Retrohippocampal region | 0 | |
| 0 | | |||
| Nek6 | sAMY | Striatum-like amygdalar nuclei | 0 | |
| 0 | | |||
| Nek6 | STR | Striatum | 0 | |
| 0 | | |||
| Nek6 | STRd | Striatum dorsal region | 0 | |
| 0 | | |||
| Nek6 | STRv | Striatum ventral region | 0 | |
| 0 | | |||
| Nek6 | TH | Thalamus | 0 | |
| 0 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00626177 | 18 | 201 | 218 | TTAAHSLVGTPYYMSPER | Peptide Atlas |