AutismKB 2.0

Annotation Detail for ZNF460


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Basic Information Top
Gene Symbol:ZNF460 ( HZF8,ZNF272 )
Gene Full Name: zinc finger protein 460
Band: 19q13.4
Quick LinksEntrez ID:10794; OMIM: 604755; Uniprot ID:ZN460_HUMAN; ENSEMBL ID: ENSG00000197714; HGNC ID: 21628
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult22 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal21 / 33603076
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain7 / 11009896
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate3 / 18934515
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis4 / 33044212
thymus1 / 8113112
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 216279_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.2
Adipocyte6.05
AdrenalCortex7.2
Adrenalgland5.5
Amygdala6.3
Appendix7.2
AtrioventricularNode5.7
BDCA4+_DentriticCells6.35
Bonemarrow6.5
BronchialEpithelialCells5.95
CD105+_Endothelial6.1
CD14+_Monocytes6.6
CD19+_BCells(neg._sel.)6.35
CD33+_Myeloid7.7
CD34+7.9
CD4+_Tcells7.8
CD56+_NKCells7.25
CD71+_EarlyErythroid5.95
CD8+_Tcells5.85
CardiacMyocytes9.8
Caudatenucleus5.6
Cerebellum5.1
CerebellumPeduncles7.3
CiliaryGanglion5.25
CingulateCortex6.6
Colorectaladenocarcinoma6.2
DorsalRootGanglion5.35
FetalThyroid6.2
Fetalbrain5.95
Fetalliver5.5
Fetallung4.7
GlobusPallidus4.8
Heart8.95
Hypothalamus6.65
Kidney5.35
Leukemia_chronicMyelogenousK-5625.65
Leukemia_promyelocytic-HL-605.45
Leukemialymphoblastic(MOLT-4)4.7
Liver9.2
Lung6.7
Lymphnode5.15
Lymphoma_burkitts(Daudi)8.1
Lymphoma_burkitts(Raji)9.25
MedullaOblongata5.65
OccipitalLobe5.55
OlfactoryBulb4.85
Ovary4.55
Pancreas5.1
PancreaticIslet6.7
ParietalLobe6.9
Pituitary7.2
Placenta6.2
Pons6.2
PrefrontalCortex7.55
Prostate7.25
Salivarygland5.15
SkeletalMuscle8.5
Skin5.25
SmoothMuscle6.9
Spinalcord6.55
SubthalamicNucleus5.85
SuperiorCervicalGanglion8.25
TemporalLobe5.85
Testis5.45
TestisGermCell5.1
TestisIntersitial5.35
TestisLeydigCell6.4
TestisSeminiferousTubule5.3
Thalamus6.45
Thymus4.65
Thyroid7.6
Tongue6.7
Tonsil6.15
Trachea5.15
TrigeminalGanglion7.3
Uterus4.95
UterusCorpus6
WholeBlood6.65
Wholebrain4.9
colon6.25
pineal_day7.7
pineal_night7.5
retina7.55
small_intestine6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_297_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.05 ± 0.15
Basal Forebrain8.17 ± 0.01
Basal Part of Pons7.82 ± 0.29
Cerebellar Cortex8.15 ± 0.27
Cerebellar Nuclei7.85 ± 0.27
Claustrum8.09 ± 0.26
Epithalamus7.98 ± 0.22
Frontal Lobe7.84 ± 0.33
Globus Pallidus8.18 ± 0.42
Hypothalamus7.83 ± 0.33
Insula7.96 ± 0.24
Limbic Lobe8.01 ± 0.35
Mesencephalon7.91 ± 0.33
Myelencephalon7.95 ± 0.29
Occipital Lobe8.09 ± 0.34
Parietal Lobe8 ± 0.33
Pontine Tegmentum7.94 ± 0.35
Striatum7.94 ± 0.35
Subthalamus7.71 ± 0.09
Temporal Lobe7.96 ± 0.29
Thalamus7.92 ± 0.29
White Matter9 ± 0.14
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00040695 18 466 483 HFSIHTGEKPYECVECGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018