AutismKB 2.0

Annotation Detail for ZNF268


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Basic Information Top
Gene Symbol:ZNF268 ( HZF3,MGC126498 )
Gene Full Name: zinc finger protein 268
Band: 12q24.33
Quick LinksEntrez ID:10795; OMIM: 604753; Uniprot ID:ZN268_HUMAN; ENSEMBL ID: ENSG00000090612; HGNC ID: 13061
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus29 / 56401251
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor13 / 26384549
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor4 / 9635941
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal96 / 336030728
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone2 / 7165527
bone marrow0 / 488010 
brain44 / 110098939
cervix0 / 481710 
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye0 / 2110540 
heart1 / 8962611
intestine5 / 23447221
kidney8 / 21177737
larynx0 / 241450 
liver7 / 20774333
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate5 / 18934526
salivary gland0 / 201550 
skin5 / 21057423
spleen3 / 5395255
stomach0 / 966190 
testis25 / 33044275
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209989_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.9
Adipocyte12.2
AdrenalCortex21.75
Adrenalgland11.15
Amygdala9.4
Appendix18.9
AtrioventricularNode19.9
BDCA4+_DentriticCells12.85
Bonemarrow14.25
BronchialEpithelialCells11.15
CD105+_Endothelial13.6
CD14+_Monocytes13.25
CD19+_BCells(neg._sel.)19.35
CD33+_Myeloid15.9
CD34+24.7
CD4+_Tcells11.85
CD56+_NKCells14.65
CD71+_EarlyErythroid12.6
CD8+_Tcells11.6
CardiacMyocytes27.5
Caudatenucleus10.7
Cerebellum9.8
CerebellumPeduncles15.35
CiliaryGanglion28.35
CingulateCortex15.4
Colorectaladenocarcinoma11.9
DorsalRootGanglion18.2
FetalThyroid15.55
Fetalbrain12
Fetalliver11.15
Fetallung7.9
GlobusPallidus12.55
Heart23.9
Hypothalamus12.85
Kidney11.7
Leukemia_chronicMyelogenousK-56210.4
Leukemia_promyelocytic-HL-609.85
Leukemialymphoblastic(MOLT-4)7.5
Liver24.8
Lung12.5
Lymphnode8.65
Lymphoma_burkitts(Daudi)16.25
Lymphoma_burkitts(Raji)19.45
MedullaOblongata11.15
OccipitalLobe11.15
OlfactoryBulb8.9
Ovary13.8
Pancreas10.35
PancreaticIslet13.45
ParietalLobe15.7
Pituitary14.35
Placenta10.4
Pons12.6
PrefrontalCortex15.2
Prostate12.7
Salivarygland11.55
SkeletalMuscle32.25
Skin19.15
SmoothMuscle14.8
Spinalcord11.45
SubthalamicNucleus12.3
SuperiorCervicalGanglion23.2
TemporalLobe11.75
Testis9.25
TestisGermCell10.35
TestisIntersitial11.6
TestisLeydigCell14.45
TestisSeminiferousTubule10.7
Thalamus12.65
Thymus7.75
Thyroid14.75
Tongue18.05
Tonsil12.85
Trachea9.15
TrigeminalGanglion18.95
Uterus9.85
UterusCorpus14.8
WholeBlood13.15
Wholebrain8.15
colon10.4
pineal_day20.12
pineal_night15.18
retina13.95
small_intestine9.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_318_PI417507815
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.15 ± 0.18
Basal Forebrain8.07 ± 0.1
Basal Part of Pons7.53 ± 0.25
Cerebellar Cortex8.26 ± 0.2
Cerebellar Nuclei7.65 ± 0.12
Claustrum7.8 ± 0.2
Epithalamus8.37 ± 0.35
Frontal Lobe7.81 ± 0.26
Globus Pallidus8.01 ± 0.41
Hypothalamus8.07 ± 0.34
Insula7.9 ± 0.27
Limbic Lobe7.93 ± 0.41
Mesencephalon8.05 ± 0.31
Myelencephalon7.98 ± 0.37
Occipital Lobe8.42 ± 0.32
Parietal Lobe8.07 ± 0.28
Pontine Tegmentum8.05 ± 0.26
Striatum8.34 ± 0.39
Subthalamus7.89 ± 0.17
Temporal Lobe7.86 ± 0.29
Thalamus7.88 ± 0.23
White Matter8.5 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Zfp26CBCerebellum0.51
1.1
Zfp26CTXCerebral cortex0.25
0.39
Zfp26HIPHippocampal region0.22
0.68
Zfp26HPFHippocampal formation0.22
0.58
Zfp26HYHypothalamus0.01
0.05
Zfp26LSXLateral septal complex0
0
Zfp26MBMidbrain0.21
0.5
Zfp26MYMedulla0.19
0.35
Zfp26OLFOlfactory bulb0.43
2.16
Zfp26PPons0.11
0.18
Zfp26PALPallidum0.02
0.06
Zfp26RHPRetrohippocampal region0.22
0.45
Zfp26sAMYStriatum-like amygdalar nuclei0.1
0.1
Zfp26STRStriatum0.06
0.09
Zfp26STRdStriatum dorsal region0.05
0.1
Zfp26STRvStriatum ventral region0.04
0.03
Zfp26THThalamus0.17
0.27
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp01039290 11 104 114 CLYRSVMLENY Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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