AutismKB 2.0

Annotation Detail for SEPT9


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Basic Information Top
Gene Symbol:SEPT9 ( AF17q25,FLJ75490,KIAA0991,MSF,MSF1,NAPB,PNUTL4,SINT1,SeptD1 )
Gene Full Name: septin 9
Band: 17q25.3
Quick LinksEntrez ID:10801; OMIM: 604061; Uniprot ID:SEPT9_HUMAN; ENSEMBL ID: ENSG00000184640; HGNC ID: 7323
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body35 / 70761494
blastocyst35 / 62319561
fetus89 / 564012157
neonate11 / 31097353
infant2 / 2362084
juvenile16 / 55556287
adult481 / 1939121248
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma6 / 17475343
breast (mammary gland) tumor87 / 94178923
cervical tumor10 / 34366290
chondrosarcoma20 / 82823241
colorectal tumor38 / 114246332
esophageal tumor5 / 17290289
gastrointestinal tumor30 / 119369251
germ cell tumor108 / 263845409
glioma25 / 106883233
head and neck tumor113 / 136302829
kidney tumor9 / 68959130
leukemia46 / 95842479
liver tumor21 / 96359217
lung tumor26 / 103127252
lymphoma53 / 71755738
non-neoplasia18 / 97250185
normal601 / 3360307178
ovarian tumor8 / 76682104
pancreatic tumor50 / 104616477
primitive neuroectodermal tumor of the CNS30 / 125680238
prostate cancer19 / 102680185
retinoblastoma15 / 46356323
skin tumor36 / 124949288
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor26 / 90257288
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland4 / 33197120
ascites8 / 40015199
bladder7 / 29757235
blood31 / 123478251
bone14 / 71655195
bone marrow2 / 4880140
brain197 / 1100989178
cervix10 / 48171207
connective tissue23 / 149255154
ear2 / 16212123
embryonic tissue84 / 215722389
esophagus5 / 20209247
eye40 / 211054189
heart17 / 89626189
intestine55 / 234472234
kidney28 / 211777132
larynx3 / 24145124
liver26 / 207743125
lung75 / 336974222
lymph46 / 442701039
lymph node50 / 91610545
mammary gland99 / 153271645
mouth98 / 670521461
muscle7 / 10771564
nerve4 / 15768253
ovary30 / 102051293
pancreas50 / 214812232
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta62 / 280825220
prostate29 / 189345153
salivary gland3 / 20155148
skin59 / 210574280
spleen25 / 53952463
stomach25 / 96619258
testis80 / 330442242
thymus154 / 811311898
thyroid10 / 47473210
tonsil6 / 16999352
trachea33 / 52413629
umbilical cord6 / 13680438
uterus75 / 232878322
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207425_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.85
Adipocyte5.05
AdrenalCortex5.5
Adrenalgland4.35
Amygdala5.15
Appendix5.05
AtrioventricularNode3.95
BDCA4+_DentriticCells12.45
Bonemarrow4.95
BronchialEpithelialCells8.15
CD105+_Endothelial5.2
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)11.75
CD33+_Myeloid6.7
CD34+6.55
CD4+_Tcells6.85
CD56+_NKCells6.6
CD71+_EarlyErythroid4.6
CD8+_Tcells7.55
CardiacMyocytes7.75
Caudatenucleus4.4
Cerebellum4.1
CerebellumPeduncles5.75
CiliaryGanglion3.55
CingulateCortex5.2
Colorectaladenocarcinoma12
DorsalRootGanglion3.8
FetalThyroid4.95
Fetalbrain4.85
Fetalliver4.4
Fetallung4.3
GlobusPallidus3.75
Heart10.4
Hypothalamus5.4
Kidney4.05
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-605.65
Leukemialymphoblastic(MOLT-4)10.6
Liver6.75
Lung5.65
Lymphnode4.85
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)26.05
MedullaOblongata4.55
OccipitalLobe4.4
OlfactoryBulb3.9
Ovary3.25
Pancreas4
PancreaticIslet5.1
ParietalLobe5.45
Pituitary5.9
Placenta5.3
Pons4.8
PrefrontalCortex6.3
Prostate6.9
Salivarygland4.3
SkeletalMuscle6
Skin3.6
SmoothMuscle6.2
Spinalcord5.25
SubthalamicNucleus4.65
SuperiorCervicalGanglion5.4
TemporalLobe4.65
Testis4.35
TestisGermCell4.55
TestisIntersitial4
TestisLeydigCell4.9
TestisSeminiferousTubule4.35
Thalamus5.1
Thymus9.4
Thyroid6.35
Tongue5
Tonsil6.2
Trachea4.25
TrigeminalGanglion5.1
Uterus4.05
UterusCorpus4.45
WholeBlood6.2
Wholebrain4.35
colon5
pineal_day6.24
pineal_night6.04
retina6.05
small_intestine5.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P106973
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.08 ± 0.38
Basal Forebrain10.98 ± 0.17
Basal Part of Pons10.85 ± 0.39
Cerebellar Cortex11.56 ± 0.29
Cerebellar Nuclei10.97 ± 0.4
Claustrum10.91 ± 0.68
Epithalamus11.38 ± 0.36
Frontal Lobe11.32 ± 0.3
Globus Pallidus10.78 ± 0.18
Hypothalamus11.41 ± 0.15
Insula11.42 ± 0.28
Limbic Lobe11.09 ± 0.49
Mesencephalon11.09 ± 0.36
Myelencephalon11.19 ± 0.37
Occipital Lobe10.81 ± 0.52
Parietal Lobe11.19 ± 0.33
Pontine Tegmentum11.17 ± 0.45
Striatum10.36 ± 0.47
Subthalamus10.92 ± 0.25
Temporal Lobe11.35 ± 0.3
Thalamus11.13 ± 0.36
White Matter10.2 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sept9CBCerebellum73.25
100
Sept9CTXCerebral cortex100
100
Sept9HIPHippocampal region100
100
Sept9HPFHippocampal formation100
100
Sept9HYHypothalamus61.31
58.55
Sept9LSXLateral septal complex14.84
12.4
Sept9MBMidbrain71.01
73.23
Sept9MYMedulla56.3
68.33
Sept9OLFOlfactory bulb90.81
93.61
Sept9PPons63.48
74.01
Sept9PALPallidum59.2
60.3
Sept9RHPRetrohippocampal region100
100
Sept9sAMYStriatum-like amygdalar nuclei68.51
62.52
Sept9STRStriatum56.79
47.62
Sept9STRdStriatum dorsal region55.54
45.73
Sept9STRvStriatum ventral region68.36
54.51
Sept9THThalamus63.63
65.55
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00007373 20 220 239 SQEATEAAPSCVGDMADTPR Peptide Atlas
SEPT9_HUMAN_0 0 0 0 RTELSIDISSK PRIDE
SEPT9_HUMAN_0 0 0 0 YLQEEVNINR PRIDE
SEPT9_HUMAN_1 10 1 10 MKKSYSGGTR PRIDE
SEPT9_HUMAN_148 15 148 162 RTEITIVKPQESAHR PRIDE
SEPT9_HUMAN_165 23 165 187 MEPPASKVPEVPTAPATDAAPKR PRIDE
SEPT9_HUMAN_195 28 195 222 PAEAPTAPSPAQTLENSEPAPVSQLQSR PRIDE
SEPT9_HUMAN_222 15 222 236 LEPKPQPPVAEATPR PRIDE
SEPT9_HUMAN_271 18 271 288 APVDFGYVGIDSILEQMR PRIDE
SEPT9_HUMAN_271 19 271 289 APVDFGYVGIDSILEQMRR PRIDE
SEPT9_HUMAN_272 18 272 289 APVDFGYVGIDSILEQMR PRIDE
SEPT9_HUMAN_357 24 357 380 LTVIDTPGFGDHINNENCWQPIMK PRIDE
SEPT9_HUMAN_389 10 389 398 YLQEEVNINR PRIDE
SEPT9_HUMAN_407 24 407 430 VHCCLYFIPATGHSLRPLDIEFMK PRIDE
SEPT9_HUMAN_435 10 435 444 VVNIVPVIAK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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