Annotation Detail for GJB6
Basic Information Top
| Gene Symbol: | GJB6 ( CX30,DFNA3,DFNA3B,DFNB1B,ED2,EDH,HED ) |
|---|---|
| Gene Full Name: | gap junction protein, beta 6, 30kDa |
| Band: | 13q12.11 |
| Quick Links | Entrez ID:10804; OMIM: 604418; Uniprot ID:CXB6_HUMAN; ENSEMBL ID: ENSG00000121742; HGNC ID: 4288 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.511757
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 10 / 564012 | 17 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 47 / 1939121 | 24 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 1 / 114246 | 8 |  |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 13 / 136302 | 95 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 32 / 97250 | 329 |  |
| normal | 45 / 3360307 | 13 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 2 / 29757 | 67 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 65 / 1100989 | 59 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 2 / 215722 | 9 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 6 / 211054 | 28 | |
| heart | 0 / 89626 | 0 | |
| intestine | 1 / 234472 | 4 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 1 / 24145 | 41 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 5 / 67052 | 74 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 8 / 41328 | 193 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_16228_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.5 ± 0.46 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.63 ± 0.45 | |
| Basal Part of Pons | 5.13 ± 0.5 | |
| Cerebellar Cortex | 5.62 ± 0.35 | |
| Cerebellar Nuclei | 6.81 ± 0.65 | |
| Claustrum | 6.34 ± 0.71 | |
| Epithalamus | 5.7 ± 0.94 | |
| Frontal Lobe | 6.05 ± 0.61 | |
| Globus Pallidus | 7.87 ± 0.48 | |
| Hypothalamus | 6.31 ± 0.44 | |
| Insula | 6.05 ± 0.63 | |
| Limbic Lobe | 5.91 ± 0.68 | |
| Mesencephalon | 6.45 ± 0.68 | |
| Myelencephalon | 6.3 ± 0.79 | |
| Occipital Lobe | 6.42 ± 0.61 | |
| Parietal Lobe | 6.39 ± 0.56 | |
| Pontine Tegmentum | 6.55 ± 0.43 | |
| Striatum | 6.72 ± 0.6 | |
| Subthalamus | 6.21 ± 0.59 | |
| Temporal Lobe | 5.95 ± 0.56 | |
| Thalamus | 6.69 ± 0.55 | |
| White Matter | 4.13 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Gjb6 | CB | Cerebellum | 50.05 | |
| 43.92 | | |||
| Gjb6 | CTX | Cerebral cortex | 17.49 | |
| 9.35 | | |||
| Gjb6 | HIP | Hippocampal region | 33.89 | |
| 19.5 | | |||
| Gjb6 | HPF | Hippocampal formation | 30.96 | |
| 17.78 | | |||
| Gjb6 | HY | Hypothalamus | 38.85 | |
| 24.77 | | |||
| Gjb6 | LSX | Lateral septal complex | 12.75 | |
| 6.51 | | |||
| Gjb6 | MB | Midbrain | 26.94 | |
| 20.73 | | |||
| Gjb6 | MY | Medulla | 38.8 | |
| 27.32 | | |||
| Gjb6 | OLF | Olfactory bulb | 15.56 | |
| 8.75 | | |||
| Gjb6 | P | Pons | 24.48 | |
| 17.74 | | |||
| Gjb6 | PAL | Pallidum | 24.75 | |
| 14.52 | | |||
| Gjb6 | RHP | Retrohippocampal region | 26.56 | |
| 14.96 | | |||
| Gjb6 | sAMY | Striatum-like amygdalar nuclei | 15.4 | |
| 8.84 | | |||
| Gjb6 | STR | Striatum | 6.34 | |
| 3.28 | | |||
| Gjb6 | STRd | Striatum dorsal region | 3.65 | |
| 1.83 | | |||
| Gjb6 | STRv | Striatum ventral region | 7.41 | |
| 3.36 | | |||
| Gjb6 | TH | Thalamus | 30.3 | |
| 20.3 | |