AutismKB 2.0

Annotation Detail for HSPH1


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Basic Information Top
Gene Symbol:HSPH1 ( DKFZp686M05240,HSP105,HSP105A,HSP105B,KIAA0201,NY-CO-25 )
Gene Full Name: heat shock 105kDa/110kDa protein 1
Band: 13q12.3
Quick LinksEntrez ID:10808; OMIM: 610703; Uniprot ID:HS105_HUMAN; ENSEMBL ID: ENSG00000120694; HGNC ID: 16969
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body18 / 70761254
blastocyst2 / 6231932
fetus94 / 564012166
neonate5 / 31097160
infant4 / 23620169
juvenile22 / 55556395
adult248 / 1939121127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma6 / 17475343
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor18 / 114246157
esophageal tumor5 / 17290289
gastrointestinal tumor23 / 119369192
germ cell tumor84 / 263845318
glioma11 / 106883102
head and neck tumor29 / 136302212
kidney tumor16 / 68959232
leukemia5 / 9584252
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma11 / 71755153
non-neoplasia8 / 9725082
normal559 / 3360307166
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS25 / 125680198
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor17 / 124949136
soft tissue/muscle tissue tumor19 / 125191151
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland6 / 33197180
ascites4 / 4001599
bladder6 / 29757201
blood15 / 123478121
bone9 / 71655125
bone marrow7 / 48801143
brain308 / 1100989279
cervix4 / 4817183
connective tissue12 / 14925580
ear3 / 16212185
embryonic tissue25 / 215722115
esophagus5 / 20209247
eye13 / 21105461
heart5 / 8962655
intestine30 / 234472127
kidney34 / 211777160
larynx2 / 2414582
liver13 / 20774362
lung42 / 336974124
lymph5 / 44270112
lymph node17 / 91610185
mammary gland11 / 15327171
mouth20 / 67052298
muscle16 / 107715148
nerve5 / 15768317
ovary4 / 10205139
pancreas15 / 21481269
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland10 / 16585602
placenta24 / 28082585
prostate8 / 18934542
salivary gland0 / 201550 
skin27 / 210574128
spleen2 / 5395237
stomach20 / 96619206
testis121 / 330442366
thymus11 / 81131135
thyroid8 / 47473168
tonsil1 / 1699958
trachea20 / 52413381
umbilical cord0 / 136800 
uterus21 / 23287890
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206976_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts620.35
Adipocyte29.1
AdrenalCortex37.05
Adrenalgland9.55
Amygdala709.1
Appendix32.05
AtrioventricularNode84.3
BDCA4+_DentriticCells103.35
Bonemarrow5.85
BronchialEpithelialCells59.5
CD105+_Endothelial446
CD14+_Monocytes53.85
CD19+_BCells(neg._sel.)86.45
CD33+_Myeloid88.8
CD34+317.7
CD4+_Tcells132.6
CD56+_NKCells129.45
CD71+_EarlyErythroid114.9
CD8+_Tcells165.55
CardiacMyocytes32.95
Caudatenucleus301.7
Cerebellum22.9
CerebellumPeduncles49.1
CiliaryGanglion41.05
CingulateCortex230.35
Colorectaladenocarcinoma485.5
DorsalRootGanglion19.7
FetalThyroid42.05
Fetalbrain372.55
Fetalliver44.35
Fetallung128
GlobusPallidus146
Heart9.6
Hypothalamus319.9
Kidney5.3
Leukemia_chronicMyelogenousK-56272
Leukemia_promyelocytic-HL-60287.7
Leukemialymphoblastic(MOLT-4)54.05
Liver8.75
Lung5.8
Lymphnode59.5
Lymphoma_burkitts(Daudi)153.95
Lymphoma_burkitts(Raji)174.9
MedullaOblongata203.25
OccipitalLobe232.35
OlfactoryBulb144.9
Ovary12.5
Pancreas141.3
PancreaticIslet78.45
ParietalLobe158.2
Pituitary154.4
Placenta7.25
Pons139.55
PrefrontalCortex427.9
Prostate54.05
Salivarygland24.95
SkeletalMuscle21.85
Skin39.25
SmoothMuscle171.4
Spinalcord66.45
SubthalamicNucleus153.55
SuperiorCervicalGanglion38.15
TemporalLobe119.75
Testis25.65
TestisGermCell136.85
TestisIntersitial90.2
TestisLeydigCell75.85
TestisSeminiferousTubule66.7
Thalamus311
Thymus29.4
Thyroid103.2
Tongue30.6
Tonsil51
Trachea49
TrigeminalGanglion51.05
Uterus88.65
UterusCorpus45.05
WholeBlood28.95
Wholebrain245.55
colon18.85
pineal_day202.56
pineal_night201.08
retina27.675
small_intestine6.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6807_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.99 ± 0.29
Basal Forebrain10.39 ± 0.26
Basal Part of Pons10.9 ± 0.38
Cerebellar Cortex10.33 ± 0.27
Cerebellar Nuclei10.34 ± 0.56
Claustrum11.23 ± 0.46
Epithalamus10.69 ± 0.57
Frontal Lobe10.82 ± 0.42
Globus Pallidus9.98 ± 0.85
Hypothalamus10.85 ± 0.31
Insula10.91 ± 0.2
Limbic Lobe11.01 ± 0.46
Mesencephalon10.67 ± 0.47
Myelencephalon10.76 ± 0.44
Occipital Lobe11.18 ± 0.33
Parietal Lobe10.92 ± 0.36
Pontine Tegmentum10.88 ± 0.38
Striatum11.44 ± 0.35
Subthalamus10.76 ± 0.3
Temporal Lobe10.83 ± 0.32
Thalamus10.94 ± 0.4
White Matter9.81 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hsp110CBCerebellum45.83
100
Hsp110CTXCerebral cortex100
100
Hsp110HIPHippocampal region100
100
Hsp110HPFHippocampal formation100
100
Hsp110HYHypothalamus100
100
Hsp110LSXLateral septal complex100
100
Hsp110MBMidbrain100
100
Hsp110MYMedulla100
100
Hsp110OLFOlfactory bulb100
100
Hsp110PPons100
100
Hsp110PALPallidum100
100
Hsp110RHPRetrohippocampal region100
100
Hsp110sAMYStriatum-like amygdalar nuclei100
100
Hsp110STRStriatum100
100
Hsp110STRdStriatum dorsal region100
100
Hsp110STRvStriatum ventral region100
100
Hsp110THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
HS105_HUMAN_0 0 0 0 AGGIETIANEFSDR PRIDE
HS105_HUMAN_0 0 0 0 EFSVTDAVPFPISLIWNHDSEDTEGVHEVFSR PRIDE
HS105_HUMAN_0 0 0 0 FQEAEERPK PRIDE
HS105_HUMAN_0 0 0 0 FVVQNVSAQK PRIDE
HS105_HUMAN_0 0 0 0 FVVQNVSAQKDGEK PRIDE
HS105_HUMAN_0 0 0 0 IEVPLYSLLEQTHLK PRIDE
HS105_HUMAN_0 0 0 0 IKELNNTCEPVVTQPKPK PRIDE
HS105_HUMAN_0 0 0 0 KPVTDCVISVPSFFTDAER PRIDE
HS105_HUMAN_0 0 0 0 NAVEEYVYEFR PRIDE
HS105_HUMAN_0 0 0 0 SVLDAAQIVGLNCLR PRIDE
HS105_HUMAN_0 0 0 0 VLGTAFDPFLGGK PRIDE
HS105_HUMAN_154 15 154 168 SVLDAAQIVGLNCLR PRIDE
HS105_HUMAN_169 27 169 195 LMNDMTAVALNYGIYKQDLPSLDEKPR PRIDE
HS105_HUMAN_186 11 186 196 QDLPSLDEKPR PRIDE
HS105_HUMAN_19 14 19 32 AGGIETIANEFSDR PRIDE
HS105_HUMAN_221 13 221 233 VLGTAFDPFLGGK PRIDE
HS105_HUMAN_239 10 239 248 LVEHFCAEFK PRIDE
HS105_HUMAN_303 13 303 315 SQFEELCAELLQK PRIDE
HS105_HUMAN_316 15 316 330 IEVPLYSLLEQTHLK PRIDE
HS105_HUMAN_360 14 360 373 DISTTLNADEAVAR PRIDE
HS105_HUMAN_374 14 374 387 GCALQCAILSPAFK PRIDE
HS105_HUMAN_390 32 390 421 EFSVTDAVPFPISLIWNHDSEDTEGVHEVFSR PRIDE
HS105_HUMAN_436 22 436 457 RGPFELEAFYSDPQGVPYPEAK PRIDE
HS105_HUMAN_590 18 590 607 VVNVELPIEANLVWQLGK PRIDE
HS105_HUMAN_635 11 635 645 NAVEEYVYEFR PRIDE
HS105_HUMAN_636 11 636 646 NAVEEYVYEFR PRIDE
HS105_HUMAN_715 8 715 722 MFEELGQR PRIDE
HS105_HUMAN_740 10 740 749 YNHIDESEMK PRIDE
PAp00000354 25 20 44 AGGIETIANEFSDRCTPSVISFGSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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