AutismKB 2.0

Annotation Detail for CPLX2


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Basic Information Top
Gene Symbol:CPLX2 ( 921-L,CPX-2,CPX2,Hfb1,MGC138492 )
Gene Full Name: complexin 2
Band: 5q35.2
Quick LinksEntrez ID:10814; OMIM: 605033; Uniprot ID:CPLX2_HUMAN; ENSEMBL ID: ENSG00000145920; HGNC ID: 2310
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant5 / 23620211
juvenile5 / 5555689
adult67 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma8 / 10688374
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor6 / 9635962
lung tumor16 / 103127155
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal551 / 3360307163
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS18 / 125680143
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain570 / 1100989517
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye6 / 21105428
heart0 / 896260 
intestine6 / 23447225
kidney0 / 2117770 
larynx1 / 2414541
liver6 / 20774328
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle1 / 1077159
nerve4 / 15768253
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206368_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte5.25
AdrenalCortex5.85
Adrenalgland4.5
Amygdala5.7
Appendix5.65
AtrioventricularNode4.55
BDCA4+_DentriticCells5.6
Bonemarrow5.2
BronchialEpithelialCells5.1
CD105+_Endothelial5.25
CD14+_Monocytes5.75
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid6.6
CD34+6.8
CD4+_Tcells5.8
CD56+_NKCells6.35
CD71+_EarlyErythroid5
CD8+_Tcells5.1
CardiacMyocytes7.65
Caudatenucleus4.75
Cerebellum4.45
CerebellumPeduncles6.05
CiliaryGanglion4.15
CingulateCortex5.8
Colorectaladenocarcinoma5.3
DorsalRootGanglion4.45
FetalThyroid5.2
Fetalbrain5.3
Fetalliver4.6
Fetallung4.15
GlobusPallidus4.05
Heart6.75
Hypothalamus5.85
Kidney4.4
Leukemia_chronicMyelogenousK-5624.8
Leukemia_promyelocytic-HL-604.65
Leukemialymphoblastic(MOLT-4)4.25
Liver7
Lung5.75
Lymphnode4.6
Lymphoma_burkitts(Daudi)6.75
Lymphoma_burkitts(Raji)7.4
MedullaOblongata4.9
OccipitalLobe4.75
OlfactoryBulb4.2
Ovary3.55
Pancreas4.35
PancreaticIslet5.65
ParietalLobe5.6
Pituitary6.2
Placenta5.45
Pons5.1
PrefrontalCortex6.7
Prostate6.1
Salivarygland4.25
SkeletalMuscle6.5
Skin4.3
SmoothMuscle6
Spinalcord5.7
SubthalamicNucleus5
SuperiorCervicalGanglion6.75
TemporalLobe4.85
Testis4.55
TestisGermCell4.4
TestisIntersitial4.5
TestisLeydigCell5.4
TestisSeminiferousTubule4.55
Thalamus5.5
Thymus4.15
Thyroid6.45
Tongue5.3
Tonsil5.2
Trachea4.45
TrigeminalGanglion5.75
Uterus4.25
UterusCorpus4.75
WholeBlood5.75
Wholebrain4.4
colon5.3
pineal_day6.74
pineal_night6.38
retina6.375
small_intestine5.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P167537
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.19 ± 0.56
Basal Forebrain7.83 ± 0.25
Basal Part of Pons7.95 ± 0.29
Cerebellar Cortex7.56 ± 0.25
Cerebellar Nuclei7.75 ± 0.25
Claustrum8.43 ± 0.45
Epithalamus7.23 ± 0.43
Frontal Lobe7.79 ± 0.47
Globus Pallidus7.72 ± 0.24
Hypothalamus7.77 ± 0.34
Insula7.73 ± 0.31
Limbic Lobe7.95 ± 0.42
Mesencephalon7.84 ± 0.61
Myelencephalon7.86 ± 0.46
Occipital Lobe7.98 ± 0.44
Parietal Lobe7.87 ± 0.37
Pontine Tegmentum7.78 ± 0.26
Striatum8.33 ± 0.43
Subthalamus7.56 ± 0.49
Temporal Lobe7.83 ± 0.43
Thalamus7.75 ± 0.4
White Matter7.17 ± 0.41
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00062936 15 84 98 AALEQPCEGSLTRPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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