AutismKB 2.0

Annotation Detail for CPLX1


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Basic Information Top
Gene Symbol:CPLX1 ( CPX-I,CPX1 )
Gene Full Name: complexin 1
Band: 4p16.3
Quick LinksEntrez ID:10815; OMIM: 605032; Uniprot ID:CPLX1_HUMAN; ENSEMBL ID: ENSG00000168993; HGNC ID: 2309
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult17 / 19391218
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal79 / 336030723
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma5 / 46356107
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain59 / 110098953
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye16 / 21105475
heart0 / 896260 
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis1 / 3304423
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P212812
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.55 ± 0.67
Basal Forebrain8.13 ± 0.34
Basal Part of Pons8.74 ± 0.59
Cerebellar Cortex7.25 ± 0.48
Cerebellar Nuclei9.02 ± 0.32
Claustrum9.13 ± 0.87
Epithalamus6.01 ± 0.95
Frontal Lobe7.63 ± 0.9
Globus Pallidus8.48 ± 0.37
Hypothalamus6.35 ± 0.58
Insula7.07 ± 0.8
Limbic Lobe7.71 ± 1
Mesencephalon7.68 ± 0.94
Myelencephalon7.87 ± 1.06
Occipital Lobe8.88 ± 0.88
Parietal Lobe8.26 ± 0.61
Pontine Tegmentum7.96 ± 0.97
Striatum8.85 ± 0.72
Subthalamus8.32 ± 0.41
Temporal Lobe7.5 ± 0.71
Thalamus8.37 ± 0.91
White Matter4.12 ± 0.96
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cplx1CBCerebellum100
100
Cplx1CTXCerebral cortex100
100
Cplx1HIPHippocampal region100
100
Cplx1HPFHippocampal formation100
100
Cplx1HYHypothalamus98.85
100
Cplx1LSXLateral septal complex100
100
Cplx1MBMidbrain100
100
Cplx1MYMedulla100
100
Cplx1OLFOlfactory bulb100
100
Cplx1PPons100
100
Cplx1PALPallidum100
100
Cplx1RHPRetrohippocampal region100
100
Cplx1sAMYStriatum-like amygdalar nuclei100
100
Cplx1STRStriatum100
100
Cplx1STRdStriatum dorsal region100
100
Cplx1STRvStriatum ventral region100
100
Cplx1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00071240 24 99 122 KAIPPGCGDEVEEEDESILDTVIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018