AutismKB 2.0

Annotation Detail for TUBGCP2


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Basic Information Top
Gene Symbol:TUBGCP2 ( GCP2,MGC138162,SPBC97,Spc97p )
Gene Full Name: tubulin, gamma complex associated protein 2
Band: 10q26.3
Quick LinksEntrez ID:10844; OMIM: NA; Uniprot ID:GCP2_HUMAN; ENSEMBL ID: ENSG00000130640; HGNC ID: 18599
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst3 / 6231948
fetus70 / 564012124
neonate1 / 3109732
infant6 / 23620254
juvenile1 / 5555617
adult145 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor4 / 34366116
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor37 / 263845140
glioma18 / 106883168
head and neck tumor13 / 13630295
kidney tumor5 / 6895972
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor13 / 103127126
lymphoma1 / 7175513
non-neoplasia6 / 9725061
normal306 / 336030791
ovarian tumor22 / 76682286
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer5 / 10268048
retinoblastoma4 / 4635686
skin tumor11 / 12494988
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone6 / 7165583
bone marrow1 / 4880120
brain120 / 1100989108
cervix5 / 48171103
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye34 / 211054161
heart1 / 8962611
intestine23 / 23447298
kidney33 / 211777155
larynx0 / 241450 
liver10 / 20774348
lung36 / 336974106
lymph0 / 442700 
lymph node8 / 9161087
mammary gland16 / 153271104
mouth11 / 67052164
muscle4 / 10771537
nerve0 / 157680 
ovary25 / 102051244
pancreas36 / 214812167
parathyroid8 / 20539389
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta9 / 28082532
prostate12 / 18934563
salivary gland1 / 2015549
skin23 / 210574109
spleen7 / 53952129
stomach3 / 9661931
testis29 / 33044287
thymus18 / 81131221
thyroid2 / 4747342
tonsil1 / 1699958
trachea4 / 5241376
umbilical cord0 / 136800 
uterus19 / 23287881
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202476_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.6
Adipocyte5.9
AdrenalCortex6.1
Adrenalgland5
Amygdala6.35
Appendix5.95
AtrioventricularNode4.35
BDCA4+_DentriticCells9.25
Bonemarrow7.15
BronchialEpithelialCells5.9
CD105+_Endothelial6
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)7.05
CD33+_Myeloid7.85
CD34+7.75
CD4+_Tcells6.55
CD56+_NKCells10.4
CD71+_EarlyErythroid5.5
CD8+_Tcells5.85
CardiacMyocytes7.5
Caudatenucleus5.35
Cerebellum4.85
CerebellumPeduncles6.7
CiliaryGanglion4.05
CingulateCortex5.95
Colorectaladenocarcinoma6.2
DorsalRootGanglion4.4
FetalThyroid5.55
Fetalbrain5.95
Fetalliver5.2
Fetallung4.75
GlobusPallidus4.35
Heart10.5
Hypothalamus6.4
Kidney6.5
Leukemia_chronicMyelogenousK-5625.35
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.85
Liver7.95
Lung6.65
Lymphnode5.1
Lymphoma_burkitts(Daudi)7.55
Lymphoma_burkitts(Raji)8.25
MedullaOblongata5.5
OccipitalLobe5.3
OlfactoryBulb4.65
Ovary4
Pancreas4.75
PancreaticIslet6.35
ParietalLobe6.25
Pituitary8.1
Placenta6.2
Pons5.65
PrefrontalCortex7.65
Prostate7.05
Salivarygland4.7
SkeletalMuscle6.85
Skin4.5
SmoothMuscle6.75
Spinalcord6.25
SubthalamicNucleus5.3
SuperiorCervicalGanglion6.8
TemporalLobe5.4
Testis5.25
TestisGermCell4.7
TestisIntersitial4.95
TestisLeydigCell5.75
TestisSeminiferousTubule5.15
Thalamus6
Thymus5.9
Thyroid7.6
Tongue5.75
Tonsil5.8
Trachea6.4
TrigeminalGanglion6.05
Uterus4.9
UterusCorpus5.3
WholeBlood6.55
Wholebrain5.15
colon6
pineal_day7.22
pineal_night7.04
retina7.1
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1090_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.3 ± 0.67
Basal Forebrain4.16 ± 0.7
Basal Part of Pons4.26 ± 0.38
Cerebellar Cortex4.31 ± 0.51
Cerebellar Nuclei3.84 ± 0.6
Claustrum4.07 ± 0.51
Epithalamus4.07 ± 0.52
Frontal Lobe4.08 ± 0.59
Globus Pallidus3.73 ± 0.84
Hypothalamus3.55 ± 0.36
Insula3.97 ± 0.39
Limbic Lobe4.01 ± 0.49
Mesencephalon3.98 ± 0.64
Myelencephalon4.06 ± 0.53
Occipital Lobe4.02 ± 0.42
Parietal Lobe4.01 ± 0.52
Pontine Tegmentum4 ± 0.54
Striatum3.7 ± 0.48
Subthalamus3.63 ± 0.73
Temporal Lobe4.19 ± 0.55
Thalamus4.08 ± 0.53
White Matter4.6 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tubgcp2CBCerebellum27.16
49.78
Tubgcp2CTXCerebral cortex100
100
Tubgcp2HIPHippocampal region100
100
Tubgcp2HPFHippocampal formation100
100
Tubgcp2HYHypothalamus37.98
40.87
Tubgcp2LSXLateral septal complex84.17
72.54
Tubgcp2MBMidbrain38.49
47.27
Tubgcp2MYMedulla26.85
42.2
Tubgcp2OLFOlfactory bulb96.21
100
Tubgcp2PPons21.93
30.91
Tubgcp2PALPallidum31.58
33.37
Tubgcp2RHPRetrohippocampal region100
100
Tubgcp2sAMYStriatum-like amygdalar nuclei35.12
32.06
Tubgcp2STRStriatum26.81
22.31
Tubgcp2STRdStriatum dorsal region21.95
18.15
Tubgcp2STRvStriatum ventral region33.74
25.94
Tubgcp2THThalamus45.48
45.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027617 21 715 735 SASNIDDVLGHHTGFLDTCLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018