AutismKB 2.0

Annotation Detail for CLPX


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Basic Information Top
Gene Symbol:CLPX ( - )
Gene Full Name: ClpX caseinolytic peptidase X homolog (E. coli)
Band: 15q22.31
Quick LinksEntrez ID:10845; OMIM: NA; Uniprot ID:CLPX_HUMAN; ENSEMBL ID: ENSG00000166855; HGNC ID: 2088
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst3 / 6231948
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor5 / 11936941
germ cell tumor17 / 26384564
glioma4 / 10688337
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia6 / 9584262
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal114 / 336030733
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood3 / 12347824
bone5 / 7165569
bone marrow5 / 48801102
brain24 / 110098921
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye9 / 21105442
heart3 / 8962633
intestine4 / 23447217
kidney11 / 21177751
larynx1 / 2414541
liver12 / 20774357
lung9 / 33697426
lymph0 / 442700 
lymph node2 / 9161021
mammary gland6 / 15327139
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta10 / 28082535
prostate2 / 18934510
salivary gland0 / 201550 
skin2 / 2105749
spleen1 / 5395218
stomach2 / 9661920
testis24 / 33044272
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204809_at
Cell line Expression level Expression bar
721_B_lymphoblasts81.25
Adipocyte19.8
AdrenalCortex31.85
Adrenalgland18.45
Amygdala20.4
Appendix32.4
AtrioventricularNode20.1
BDCA4+_DentriticCells116.25
Bonemarrow17.55
BronchialEpithelialCells64.45
CD105+_Endothelial68.85
CD14+_Monocytes37.6
CD19+_BCells(neg._sel.)60.45
CD33+_Myeloid51.55
CD34+48.3
CD4+_Tcells42.15
CD56+_NKCells76.65
CD71+_EarlyErythroid53.75
CD8+_Tcells62
CardiacMyocytes27.35
Caudatenucleus12.6
Cerebellum13
CerebellumPeduncles29.3
CiliaryGanglion20.1
CingulateCortex13.7
Colorectaladenocarcinoma40.55
DorsalRootGanglion23.8
FetalThyroid22.5
Fetalbrain17.2
Fetalliver22.3
Fetallung16.9
GlobusPallidus12.4
Heart27.9
Hypothalamus16.6
Kidney10.25
Leukemia_chronicMyelogenousK-56262.35
Leukemia_promyelocytic-HL-60104.9
Leukemialymphoblastic(MOLT-4)19.65
Liver23.25
Lung15.3
Lymphnode17.75
Lymphoma_burkitts(Daudi)53.95
Lymphoma_burkitts(Raji)98.25
MedullaOblongata11.6
OccipitalLobe17.9
OlfactoryBulb14.3
Ovary14
Pancreas22.9
PancreaticIslet25.8
ParietalLobe16.8
Pituitary13.1
Placenta17.75
Pons19.95
PrefrontalCortex17.6
Prostate23.5
Salivarygland16
SkeletalMuscle36.25
Skin23.85
SmoothMuscle30.5
Spinalcord15.6
SubthalamicNucleus16.45
SuperiorCervicalGanglion49.35
TemporalLobe11.75
Testis39.85
TestisGermCell43.1
TestisIntersitial50.5
TestisLeydigCell29.4
TestisSeminiferousTubule41.85
Thalamus18.1
Thymus13.15
Thyroid44.9
Tongue23.85
Tonsil24.25
Trachea13.35
TrigeminalGanglion21.05
Uterus29.8
UterusCorpus26.6
WholeBlood41
Wholebrain11.4
colon64.85
pineal_day34.04
pineal_night75.52
retina23.675
small_intestine35.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12197_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.32 ± 0.24
Basal Forebrain9.27 ± 0.25
Basal Part of Pons9.09 ± 0.19
Cerebellar Cortex9.08 ± 0.18
Cerebellar Nuclei9.3 ± 0.24
Claustrum9.29 ± 0.37
Epithalamus9.47 ± 0.24
Frontal Lobe9.13 ± 0.24
Globus Pallidus9.58 ± 0.09
Hypothalamus9.03 ± 0.27
Insula9.11 ± 0.17
Limbic Lobe9.19 ± 0.26
Mesencephalon9.29 ± 0.24
Myelencephalon9.2 ± 0.27
Occipital Lobe9.46 ± 0.24
Parietal Lobe9.25 ± 0.21
Pontine Tegmentum9.25 ± 0.26
Striatum9.4 ± 0.21
Subthalamus9.32 ± 0.14
Temporal Lobe9.11 ± 0.22
Thalamus9.26 ± 0.21
White Matter9.81 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
ClpxCBCerebellum35.17
50.17
ClpxCTXCerebral cortex71.75
54.75
ClpxHIPHippocampal region49.27
70.9
ClpxHPFHippocampal formation55.84
63.4
ClpxHYHypothalamus39.34
29.76
ClpxLSXLateral septal complex66.35
51.42
ClpxMBMidbrain39.03
34.77
ClpxMYMedulla37.76
39.44
ClpxOLFOlfactory bulb64.79
53.89
ClpxPPons39.16
39.33
ClpxPALPallidum41.21
37.18
ClpxRHPRetrohippocampal region67.41
54.39
ClpxsAMYStriatum-like amygdalar nuclei64.97
48.22
ClpxSTRStriatum59.04
42.87
ClpxSTRdStriatum dorsal region58.24
41.87
ClpxSTRvStriatum ventral region55.99
39.57
ClpxTHThalamus70.31
66.06
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CLPX_HUMAN_211 14 211 224 QQAEVEKQTSLTPR PRIDE
CLPX_HUMAN_486 14 486 499 DLIEFGMIPEFVGR PRIDE
PAp00001055 15 130 144 CHHFFVVLSEADSKK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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