AutismKB 2.0

Annotation Detail for WDR3


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Basic Information Top
Gene Symbol:WDR3 ( FLJ12796 )
Gene Full Name: WD repeat domain 3
Band: 1p12
Quick LinksEntrez ID:10885; OMIM: 604737; Uniprot ID:WDR3_HUMAN; ENSEMBL ID: ENSG00000065183; HGNC ID: 12755
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus8 / 56401214
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult40 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor24 / 26384590
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal49 / 336030714
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor13 / 124949104
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder2 / 2975767
blood0 / 1234780 
bone2 / 7165527
bone marrow2 / 4880140
brain7 / 11009896
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine4 / 23447217
kidney1 / 2117774
larynx1 / 2414541
liver1 / 2077434
lung10 / 33697429
lymph1 / 4427022
lymph node8 / 9161087
mammary gland5 / 15327132
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary3 / 10205129
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta3 / 28082510
prostate2 / 18934510
salivary gland0 / 201550 
skin14 / 21057466
spleen2 / 5395237
stomach1 / 9661910
testis15 / 33044245
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus5 / 23287821
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218882_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts100.15
Adipocyte10.7
AdrenalCortex10.65
Adrenalgland7.85
Amygdala9.3
Appendix10.05
AtrioventricularNode7.75
BDCA4+_DentriticCells9.35
Bonemarrow9
BronchialEpithelialCells33.65
CD105+_Endothelial80.9
CD14+_Monocytes9.4
CD19+_BCells(neg._sel.)15.7
CD33+_Myeloid16.75
CD34+64.95
CD4+_Tcells15.05
CD56+_NKCells24.65
CD71+_EarlyErythroid7.95
CD8+_Tcells19.8
CardiacMyocytes14.7
Caudatenucleus7.75
Cerebellum7.15
CerebellumPeduncles9.9
CiliaryGanglion6.85
CingulateCortex8.85
Colorectaladenocarcinoma9.3
DorsalRootGanglion7.4
FetalThyroid9.15
Fetalbrain11.2
Fetalliver7.55
Fetallung8.1
GlobusPallidus6.5
Heart11.85
Hypothalamus10.1
Kidney7.05
Leukemia_chronicMyelogenousK-56215.85
Leukemia_promyelocytic-HL-6043.8
Leukemialymphoblastic(MOLT-4)16
Liver12
Lung8.75
Lymphnode8.9
Lymphoma_burkitts(Daudi)40.55
Lymphoma_burkitts(Raji)23.2
MedullaOblongata8.95
OccipitalLobe7.5
OlfactoryBulb6.7
Ovary6.1
Pancreas7.6
PancreaticIslet9.4
ParietalLobe9.5
Pituitary16.75
Placenta8
Pons10.5
PrefrontalCortex10
Prostate9.9
Salivarygland7
SkeletalMuscle16.45
Skin7.2
SmoothMuscle12.25
Spinalcord10.3
SubthalamicNucleus8
SuperiorCervicalGanglion11.2
TemporalLobe8.1
Testis7.6
TestisGermCell11.5
TestisIntersitial8.15
TestisLeydigCell10.4
TestisSeminiferousTubule11.35
Thalamus8.55
Thymus6.65
Thyroid15.4
Tongue9.05
Tonsil12.7
Trachea7.15
TrigeminalGanglion10.15
Uterus8.7
UterusCorpus12.05
WholeBlood10.8
Wholebrain6.9
colon9.15
pineal_day14.02
pineal_night11.06
retina9.8
small_intestine8.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P122524
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.43
Basal Forebrain4.92 ± 0.27
Basal Part of Pons5.19 ± 0.43
Cerebellar Cortex5.24 ± 0.27
Cerebellar Nuclei5.02 ± 0.57
Claustrum4.77 ± 0.74
Epithalamus5.01 ± 0.44
Frontal Lobe5.35 ± 0.37
Globus Pallidus4.71 ± 0.27
Hypothalamus5.56 ± 0.49
Insula5.34 ± 0.43
Limbic Lobe5.15 ± 0.56
Mesencephalon5.21 ± 0.44
Myelencephalon5.14 ± 0.48
Occipital Lobe4.87 ± 0.47
Parietal Lobe5.16 ± 0.43
Pontine Tegmentum5.19 ± 0.55
Striatum5.08 ± 0.55
Subthalamus5.58 ± 0.48
Temporal Lobe5.29 ± 0.36
Thalamus5.08 ± 0.4
White Matter4.7 ± 0.51
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wdr3CBCerebellum55.45
62.86
Wdr3CTXCerebral cortex13.43
9.8
Wdr3HIPHippocampal region24.36
28.76
Wdr3HPFHippocampal formation18.86
19.94
Wdr3HYHypothalamus5.07
4.52
Wdr3LSXLateral septal complex25.96
23.16
Wdr3MBMidbrain9.23
9.67
Wdr3MYMedulla17.39
18.25
Wdr3OLFOlfactory bulb21.51
19.26
Wdr3PPons11.97
12.15
Wdr3PALPallidum2.05
2.22
Wdr3RHPRetrohippocampal region8.79
7.03
Wdr3sAMYStriatum-like amygdalar nuclei3.84
3.23
Wdr3STRStriatum3.53
3.37
Wdr3STRdStriatum dorsal region2.34
2.63
Wdr3STRvStriatum ventral region6.28
4.78
Wdr3THThalamus6.22
8.11
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00065866 19 730 748 EDQPAVPGETQGDSYFTGK Peptide Atlas
WDR3_HUMAN_2 8 2 9 GLTKQYLR PRIDE
WDR3_HUMAN_239 26 239 264 GSSPGIQDTLEAEDGAFETDEAPEDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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