Annotation Detail for MALT1
Basic Information Top
| Gene Symbol: | MALT1 ( DKFZp434L132,MLT,MLT1 ) |
|---|---|
| Gene Full Name: | mucosa associated lymphoid tissue lymphoma translocation gene 1 |
| Band: | 18q21.32 |
| Quick Links | Entrez ID:10892; OMIM: 604860; Uniprot ID:MALT1_HUMAN; ENSEMBL ID: ENSG00000172175; HGNC ID: 6819 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.601217
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 4 / 70761 | 56 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 6 / 564012 | 10 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 46 / 1939121 | 23 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 2 / 17475 | 114 | |
| breast (mammary gland) tumor | 4 / 94178 | 42 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 3 / 95842 | 31 | |
| liver tumor | 4 / 96359 | 41 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 68 / 3360307 | 20 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 6 / 102680 | 58 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 6 / 123478 | 48 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 6 / 1100989 | 5 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 3 / 211054 | 14 | |
| heart | 0 / 89626 | 0 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 9 / 207743 | 43 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 5 / 214812 | 23 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 8 / 189345 | 42 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 9 / 330442 | 27 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 3 / 232878 | 12 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 208309_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 111.35 | |
| Adipocyte | 4.45 | |
| AdrenalCortex | 4.5 | |
| Adrenalgland | 3.6 | |
| Amygdala | 4.55 | |
| Appendix | 4.35 | |
| AtrioventricularNode | 3.3 | |
| BDCA4+_DentriticCells | 110.95 | |
| Bonemarrow | 4.25 | |
| BronchialEpithelialCells | 17.45 | |
| CD105+_Endothelial | 4.35 | |
| CD14+_Monocytes | 39.15 | |
| CD19+_BCells(neg._sel.) | 207.35 |  |
| CD33+_Myeloid | 44.75 | |
| CD34+ | 5.85 | |
| CD4+_Tcells | 82.7 | |
| CD56+_NKCells | 104.95 | |
| CD71+_EarlyErythroid | 4 | |
| CD8+_Tcells | 52.75 | |
| CardiacMyocytes | 5.55 | |
| Caudatenucleus | 3.85 | |
| Cerebellum | 3.45 | |
| CerebellumPeduncles | 4.85 | |
| CiliaryGanglion | 3.05 | |
| CingulateCortex | 4.35 | |
| Colorectaladenocarcinoma | 4.7 | |
| DorsalRootGanglion | 3.25 | |
| FetalThyroid | 4.2 | |
| Fetalbrain | 4.3 | |
| Fetalliver | 3.7 | |
| Fetallung | 3.75 | |
| GlobusPallidus | 3.05 | |
| Heart | 5.45 | |
| Hypothalamus | 4.7 | |
| Kidney | 3.45 | |
| Leukemia_chronicMyelogenousK-562 | 20.3 | |
| Leukemia_promyelocytic-HL-60 | 67.5 | |
| Leukemialymphoblastic(MOLT-4) | 3.45 | |
| Liver | 5.7 | |
| Lung | 4.75 | |
| Lymphnode | 18.8 | |
| Lymphoma_burkitts(Daudi) | 9.55 | |
| Lymphoma_burkitts(Raji) | 7.95 | |
| MedullaOblongata | 3.9 | |
| OccipitalLobe | 3.85 | |
| OlfactoryBulb | 3.4 | |
| Ovary | 2.85 | |
| Pancreas | 3.5 | |
| PancreaticIslet | 4.65 | |
| ParietalLobe | 4.45 | |
| Pituitary | 5.05 | |
| Placenta | 4.55 | |
| Pons | 4.1 | |
| PrefrontalCortex | 5.2 | |
| Prostate | 5.5 | |
| Salivarygland | 3.5 | |
| SkeletalMuscle | 4.95 | |
| Skin | 3.3 | |
| SmoothMuscle | 15.65 | |
| Spinalcord | 4.55 | |
| SubthalamicNucleus | 3.85 | |
| SuperiorCervicalGanglion | 4.85 | |
| TemporalLobe | 3.95 | |
| Testis | 4.05 | |
| TestisGermCell | 8.8 | |
| TestisIntersitial | 4.25 | |
| TestisLeydigCell | 4.8 | |
| TestisSeminiferousTubule | 9.35 | |
| Thalamus | 4.35 | |
| Thymus | 3.4 | |
| Thyroid | 5.55 | |
| Tongue | 4.2 | |
| Tonsil | 42.7 | |
| Trachea | 3.6 | |
| TrigeminalGanglion | 4.4 | |
| Uterus | 3.55 | |
| UterusCorpus | 3.85 | |
| WholeBlood | 8.05 | |
| Wholebrain | 3.6 | |
| colon | 4.35 | |
| pineal_day | 19.92 | |
| pineal_night | 12.78 | |
| retina | 5.175 | |
| small_intestine | 4.2 | |
- Probe name: A_23_P96008
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 3.65 ± 0.62 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 3.53 ± 0.4 | |
| Basal Part of Pons | 3.52 ± 0.49 | |
| Cerebellar Cortex | 3.98 ± 0.41 | |
| Cerebellar Nuclei | 3.65 ± 0.44 | |
| Claustrum | 2.99 ± 0.69 | |
| Epithalamus | 3.72 ± 0.5 | |
| Frontal Lobe | 3.64 ± 0.39 | |
| Globus Pallidus | 3.55 ± 0.45 | |
| Hypothalamus | 3.82 ± 0.56 | |
| Insula | 3.94 ± 0.3 | |
| Limbic Lobe | 3.58 ± 0.47 | |
| Mesencephalon | 3.63 ± 0.62 | |
| Myelencephalon | 3.59 ± 0.5 | |
| Occipital Lobe | 3.75 ± 0.45 | |
| Parietal Lobe | 3.63 ± 0.54 | |
| Pontine Tegmentum | 3.65 ± 0.4 | |
| Striatum | 3.32 ± 0.46 | |
| Subthalamus | 3.91 ± 0.29 | |
| Temporal Lobe | 3.64 ± 0.47 | |
| Thalamus | 3.53 ± 0.5 | |
| White Matter | 3.13 ± 0.2 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Malt1 | CB | Cerebellum | 74.67 | |
| 100 | | |||
| Malt1 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Malt1 | HIP | Hippocampal region | 64.14 | |
| 88.33 | | |||
| Malt1 | HPF | Hippocampal formation | 77.97 | |
| 88.77 | | |||
| Malt1 | HY | Hypothalamus | 62.28 | |
| 52.72 | | |||
| Malt1 | LSX | Lateral septal complex | 100 | |
| 100 | | |||
| Malt1 | MB | Midbrain | 59 | |
| 55.21 | | |||
| Malt1 | MY | Medulla | 55.84 | |
| 55.37 | | |||
| Malt1 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Malt1 | P | Pons | 43.62 | |
| 38.55 | | |||
| Malt1 | PAL | Pallidum | 49.84 | |
| 51.58 | | |||
| Malt1 | RHP | Retrohippocampal region | 98.43 | |
| 87.89 | | |||
| Malt1 | sAMY | Striatum-like amygdalar nuclei | 57.39 | |
| 47.4 | | |||
| Malt1 | STR | Striatum | 89.69 | |
| 75.03 | | |||
| Malt1 | STRd | Striatum dorsal region | 83.87 | |
| 68.08 | | |||
| Malt1 | STRv | Striatum ventral region | 97.01 | |
| 87.52 | | |||
| Malt1 | TH | Thalamus | 73.76 | |
| 63.29 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| MALT1_HUMAN_2 | 31 | 2 | 32 | SLLGDPLQALPPSAAPTGPLLAPPAGATLNR | PRIDE |
| PAp00503706 | 14 | 457 | 470 | NDYDDTIPILDALK | Peptide Atlas |