Annotation Detail for TRAFD1
Basic Information Top
| Gene Symbol: | TRAFD1 ( FLN29 ) |
|---|---|
| Gene Full Name: | TRAF-type zinc finger domain containing 1 |
| Band: | 12q24.13 |
| Quick Links | Entrez ID:10906; OMIM: 613197; Uniprot ID:TRAD1_HUMAN; ENSEMBL ID: ENSG00000135148; HGNC ID: 24808 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.5148
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 30 / 564012 | 53 |  |
| neonate | 2 / 31097 | 64 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 6 / 55556 | 107 | |
| adult | 111 / 1939121 | 57 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 9 / 94178 | 95 | |
| cervical tumor | 4 / 34366 | 116 | |
| chondrosarcoma | 6 / 82823 | 72 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 47 / 263845 | 178 | |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 12 / 136302 | 88 | |
| kidney tumor | 6 / 68959 | 87 | |
| leukemia | 8 / 95842 | 83 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 5 / 103127 | 48 | |
| lymphoma | 8 / 71755 | 111 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 252 / 3360307 | 74 | |
| ovarian tumor | 14 / 76682 | 182 | |
| pancreatic tumor | 9 / 104616 | 86 | |
| primitive neuroectodermal tumor of the CNS | 9 / 125680 | 71 | |
| prostate cancer | 9 / 102680 | 87 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 18 / 124949 | 144 | |
| soft tissue/muscle tissue tumor | 11 / 125191 | 87 | |
| uterine tumor | 9 / 90257 | 99 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 2 / 13106 | 152 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 4 / 29757 | 134 | |
| blood | 19 / 123478 | 153 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 83 / 1100989 | 75 | |
| cervix | 5 / 48171 | 103 | |
| connective tissue | 10 / 149255 | 66 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 10 / 215722 | 46 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 12 / 211054 | 56 | |
| heart | 4 / 89626 | 44 | |
| intestine | 14 / 234472 | 59 | |
| kidney | 13 / 211777 | 61 | |
| larynx | 0 / 24145 | 0 | |
| liver | 12 / 207743 | 57 | |
| lung | 23 / 336974 | 68 | |
| lymph | 5 / 44270 | 112 | |
| lymph node | 14 / 91610 | 152 | |
| mammary gland | 11 / 153271 | 71 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 19 / 102051 | 186 | |
| pancreas | 9 / 214812 | 41 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 9 / 41328 | 217 |  |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 15 / 189345 | 79 | |
| salivary gland | 6 / 20155 | 297 | |
| skin | 27 / 210574 | 128 | |
| spleen | 13 / 53952 | 240 | |
| stomach | 4 / 96619 | 41 | |
| testis | 31 / 330442 | 93 | |
| thymus | 5 / 81131 | 61 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 7 / 16999 | 411 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 19 / 232878 | 81 | |
| vascular | 1 / 51780 | 19 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 35254_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 35.95 | |
| Adipocyte | 10 |  |
| AdrenalCortex | 17.55 | |
| Adrenalgland | 10.6 | |
| Amygdala | 9.65 | |
| Appendix | 13.8 | |
| AtrioventricularNode | 12 | |
| BDCA4+_DentriticCells | 29.1 | |
| Bonemarrow | 13.75 | |
| BronchialEpithelialCells | 11.3 | |
| CD105+_Endothelial | 13.5 | |
| CD14+_Monocytes | 55.9 | |
| CD19+_BCells(neg._sel.) | 13.7 | |
| CD33+_Myeloid | 20.25 | |
| CD34+ | 13.95 | |
| CD4+_Tcells | 20.85 | |
| CD56+_NKCells | 40.25 | |
| CD71+_EarlyErythroid | 11.3 | |
| CD8+_Tcells | 15.8 | |
| CardiacMyocytes | 14.1 | |
| Caudatenucleus | 9.3 | |
| Cerebellum | 10.8 | |
| CerebellumPeduncles | 12.7 | |
| CiliaryGanglion | 8.35 | |
| CingulateCortex | 11.95 | |
| Colorectaladenocarcinoma | 10.25 | |
| DorsalRootGanglion | 9.35 | |
| FetalThyroid | 11.4 | |
| Fetalbrain | 12.15 | |
| Fetalliver | 7.95 | |
| Fetallung | 10.35 | |
| GlobusPallidus | 10.1 | |
| Heart | 15.9 | |
| Hypothalamus | 12.25 | |
| Kidney | 8.55 | |
| Leukemia_chronicMyelogenousK-562 | 18.95 | |
| Leukemia_promyelocytic-HL-60 | 9.95 | |
| Leukemialymphoblastic(MOLT-4) | 11.65 | |
| Liver | 13.65 | |
| Lung | 12.25 | |
| Lymphnode | 10.55 | |
| Lymphoma_burkitts(Daudi) | 13.6 | |
| Lymphoma_burkitts(Raji) | 16.5 | |
| MedullaOblongata | 9.75 | |
| OccipitalLobe | 9.5 | |
| OlfactoryBulb | 9.5 | |
| Ovary | 8.4 | |
| Pancreas | 9.95 | |
| PancreaticIslet | 12.85 | |
| ParietalLobe | 13.3 | |
| Pituitary | 11.85 | |
| Placenta | 11.45 | |
| Pons | 11.55 | |
| PrefrontalCortex | 13.45 | |
| Prostate | 14.25 | |
| Salivarygland | 8.75 | |
| SkeletalMuscle | 23.55 | |
| Skin | 12.05 | |
| SmoothMuscle | 10.75 | |
| Spinalcord | 12.6 | |
| SubthalamicNucleus | 11.55 | |
| SuperiorCervicalGanglion | 13.7 | |
| TemporalLobe | 10.45 | |
| Testis | 35.3 | |
| TestisGermCell | 15.1 | |
| TestisIntersitial | 15.4 | |
| TestisLeydigCell | 16.25 | |
| TestisSeminiferousTubule | 13.55 | |
| Thalamus | 12.15 | |
| Thymus | 14.4 | |
| Thyroid | 11.45 | |
| Tongue | 14.25 | |
| Tonsil | 11.9 | |
| Trachea | 9.35 | |
| TrigeminalGanglion | 13 | |
| Uterus | 8.95 | |
| UterusCorpus | 11.8 | |
| WholeBlood | 45.3 | |
| Wholebrain | 9.05 | |
| colon | 10.45 | |
| pineal_day | 14.36 | |
| pineal_night | 13.52 | |
| retina | 17.925 | |
| small_intestine | 8.85 | |
- Probe name: A_23_P128541
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.06 ± 0.72 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.09 ± 0.69 | |
| Basal Part of Pons | 3.9 ± 0.61 | |
| Cerebellar Cortex | 3.93 ± 0.42 | |
| Cerebellar Nuclei | 4.18 ± 0.68 | |
| Claustrum | 4.14 ± 0.96 | |
| Epithalamus | 3.8 ± 0.29 | |
| Frontal Lobe | 3.76 ± 0.57 | |
| Globus Pallidus | 4.74 ± 0.43 | |
| Hypothalamus | 3.61 ± 0.75 | |
| Insula | 3.41 ± 0.65 | |
| Limbic Lobe | 3.91 ± 0.6 | |
| Mesencephalon | 3.96 ± 0.59 | |
| Myelencephalon | 3.86 ± 0.61 | |
| Occipital Lobe | 4.04 ± 0.61 | |
| Parietal Lobe | 3.83 ± 0.69 | |
| Pontine Tegmentum | 3.95 ± 0.7 | |
| Striatum | 3.86 ± 0.58 | |
| Subthalamus | 4.42 ± 0.58 | |
| Temporal Lobe | 3.81 ± 0.61 | |
| Thalamus | 3.93 ± 0.65 | |
| White Matter | 5.77 ± 0.58 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Trafd1 | CB | Cerebellum | 35.51 | |
| 60.64 | | |||
| Trafd1 | CTX | Cerebral cortex | 100 | |
| 95.75 | | |||
| Trafd1 | HIP | Hippocampal region | 75.79 | |
| 100 | | |||
| Trafd1 | HPF | Hippocampal formation | 90.6 | |
| 100 | | |||
| Trafd1 | HY | Hypothalamus | 81.36 | |
| 67.52 | | |||
| Trafd1 | LSX | Lateral septal complex | 76.71 | |
| 61.09 | | |||
| Trafd1 | MB | Midbrain | 52.77 | |
| 49.02 | | |||
| Trafd1 | MY | Medulla | 37.72 | |
| 45.34 | | |||
| Trafd1 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Trafd1 | P | Pons | 54.74 | |
| 59.42 | | |||
| Trafd1 | PAL | Pallidum | 67.7 | |
| 62.42 | | |||
| Trafd1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Trafd1 | sAMY | Striatum-like amygdalar nuclei | 89.15 | |
| 76.45 | | |||
| Trafd1 | STR | Striatum | 52.1 | |
| 42.44 | | |||
| Trafd1 | STRd | Striatum dorsal region | 36.71 | |
| 29.95 | | |||
| Trafd1 | STRv | Striatum ventral region | 75.94 | |
| 57.05 | | |||
| Trafd1 | TH | Thalamus | 78 | |
| 67.08 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00005039 | 11 | 102 | 112 | LKEHEDYCGAR | Peptide Atlas |
| TRAD1_HUMAN_2 | 10 | 2 | 11 | AEFLDDQETR | PRIDE |
| TRAD1_HUMAN_407 | 14 | 407 | 420 | LDSQPQETSPELPR | PRIDE |