AutismKB 2.0

Annotation Detail for SUGT1


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Basic Information Top
Gene Symbol:SUGT1 ( SGT1 )
Gene Full Name: SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
Band: 13q14.3
Quick LinksEntrez ID:10910; OMIM: 604098; Uniprot ID:SUGT1_HUMAN; ENSEMBL ID: ENSG00000165416; HGNC ID: 16987
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus17 / 56401230
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult95 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor2 / 3436658
chondrosarcoma6 / 8282372
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor10 / 26384537
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal108 / 336030732
ovarian tumor1 / 7668213
pancreatic tumor24 / 104616229
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor16 / 124949128
soft tissue/muscle tissue tumor54 / 125191431
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood6 / 12347848
bone2 / 7165527
bone marrow1 / 4880120
brain29 / 110098926
cervix2 / 4817141
connective tissue46 / 149255308
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine4 / 23447217
kidney8 / 21177737
larynx0 / 241450 
liver8 / 20774338
lung21 / 33697462
lymph0 / 442700 
lymph node1 / 9161010
mammary gland6 / 15327139
mouth0 / 670520 
muscle6 / 10771555
nerve2 / 15768126
ovary2 / 10205119
pancreas30 / 214812139
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta13 / 28082546
prostate4 / 18934521
salivary gland2 / 2015599
skin19 / 21057490
spleen0 / 539520 
stomach10 / 96619103
testis8 / 33044224
thymus0 / 811310 
thyroid1 / 4747321
tonsil5 / 16999294
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P162787
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.54 ± 0.11
Basal Forebrain10.48 ± 0.2
Basal Part of Pons10.54 ± 0.14
Cerebellar Cortex10.39 ± 0.12
Cerebellar Nuclei10.58 ± 0.15
Claustrum10.59 ± 0.14
Epithalamus10.34 ± 0.28
Frontal Lobe10.58 ± 0.22
Globus Pallidus10.99 ± 0.12
Hypothalamus10.59 ± 0.14
Insula10.66 ± 0.2
Limbic Lobe10.66 ± 0.24
Mesencephalon10.59 ± 0.24
Myelencephalon10.55 ± 0.26
Occipital Lobe10.44 ± 0.24
Parietal Lobe10.53 ± 0.2
Pontine Tegmentum10.62 ± 0.27
Striatum10.8 ± 0.19
Subthalamus10.78 ± 0.08
Temporal Lobe10.53 ± 0.18
Thalamus10.54 ± 0.18
White Matter11.46 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sugt1CBCerebellum56.83
91.26
Sugt1CTXCerebral cortex100
100
Sugt1HIPHippocampal region99.3
100
Sugt1HPFHippocampal formation100
100
Sugt1HYHypothalamus59.63
54.08
Sugt1LSXLateral septal complex58.7
42.63
Sugt1MBMidbrain78.22
80.08
Sugt1MYMedulla83.71
100
Sugt1OLFOlfactory bulb100
100
Sugt1PPons73.28
90.08
Sugt1PALPallidum67.05
72.32
Sugt1RHPRetrohippocampal region100
100
Sugt1sAMYStriatum-like amygdalar nuclei100
100
Sugt1STRStriatum92.35
80.82
Sugt1STRdStriatum dorsal region92.27
79.39
Sugt1STRvStriatum ventral region89.9
77.41
Sugt1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000529 15 37 51 ALEQKPDDAQYYCQR Peptide Atlas
SUGT1_HUMAN_1 12 1 12 AAAAAGTATSQR PRIDE
SUGT1_HUMAN_2 12 2 13 AAAAAGTATSQR PRIDE
SUGT1_HUMAN_311 15 311 325 LFQQIYSDGSDEVKR PRIDE
SUGT1_HUMAN_36 15 36 50 ALEQKPDDAQYYCQR PRIDE
SUGT1_HUMAN_70 14 70 83 SLELNPNNSTAMLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018