AutismKB 2.0

Annotation Detail for GADD45G


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Basic Information Top
Gene Symbol:GADD45G ( CR6,DDIT2,GADD45gamma,GRP17 )
Gene Full Name: growth arrest and DNA-damage-inducible, gamma
Band: 9q22.2
Quick LinksEntrez ID:10912; OMIM: 604949; Uniprot ID:GA45G_HUMAN; ENSEMBL ID: ENSG00000130222; HGNC ID: 4097
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor3 / 26384511
glioma14 / 106883130
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor10 / 10312796
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal142 / 336030742
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain23 / 110098920
cervix1 / 4817120
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye13 / 21105461
heart1 / 8962611
intestine4 / 23447217
kidney8 / 21177737
larynx0 / 241450 
liver6 / 20774328
lung27 / 33697480
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas32 / 214812148
parathyroid3 / 20539146
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta36 / 280825128
prostate12 / 18934563
salivary gland2 / 2015599
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204121_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte3.4
AdrenalCortex3.85
Adrenalgland2.9
Amygdala3.7
Appendix3.45
AtrioventricularNode2.6
BDCA4+_DentriticCells3.8
Bonemarrow3.4
BronchialEpithelialCells3.45
CD105+_Endothelial3.5
CD14+_Monocytes3.7
CD19+_BCells(neg._sel.)3.7
CD33+_Myeloid4.45
CD34+4.35
CD4+_Tcells3.8
CD56+_NKCells4.15
CD71+_EarlyErythroid16.7
CD8+_Tcells3.4
CardiacMyocytes4.4
Caudatenucleus3.05
Cerebellum2.8
CerebellumPeduncles3.85
CiliaryGanglion2.35
CingulateCortex3.5
Colorectaladenocarcinoma3.45
DorsalRootGanglion2.6
FetalThyroid3.35
Fetalbrain3.5
Fetalliver2.95
Fetallung2.95
GlobusPallidus2.5
Heart4.35
Hypothalamus3.85
Kidney2.75
Leukemia_chronicMyelogenousK-5623.1
Leukemia_promyelocytic-HL-603.05
Leukemialymphoblastic(MOLT-4)2.8
Liver4.5
Lung6.25
Lymphnode2.95
Lymphoma_burkitts(Daudi)4.35
Lymphoma_burkitts(Raji)4.8
MedullaOblongata3.15
OccipitalLobe3.1
OlfactoryBulb3.4
Ovary2.25
Pancreas2.75
PancreaticIslet36.5
ParietalLobe3.6
Pituitary4
Placenta210.25
Pons3.25
PrefrontalCortex4.35
Prostate28.65
Salivarygland2.7
SkeletalMuscle3.9
Skin2.6
SmoothMuscle3.9
Spinalcord3.7
SubthalamicNucleus3.1
SuperiorCervicalGanglion3.85
TemporalLobe3.1
Testis3
TestisGermCell3.25
TestisIntersitial2.9
TestisLeydigCell3.4
TestisSeminiferousTubule2.95
Thalamus3.45
Thymus2.75
Thyroid4.4
Tongue3.35
Tonsil3.35
Trachea2.9
TrigeminalGanglion3.4
Uterus7.85
UterusCorpus29.85
WholeBlood3.8
Wholebrain2.95
colon3.5
pineal_day140.5
pineal_night87.16
retina4.225
small_intestine3.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P120934
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.63 ± 0.59
Basal Forebrain3.8 ± 0.62
Basal Part of Pons3.75 ± 0.47
Cerebellar Cortex4.43 ± 0.41
Cerebellar Nuclei3.88 ± 0.36
Claustrum3.17 ± 0.76
Epithalamus4.47 ± 0.87
Frontal Lobe3.83 ± 0.6
Globus Pallidus3.71 ± 0.34
Hypothalamus3.96 ± 0.76
Insula3.75 ± 0.63
Limbic Lobe3.54 ± 0.7
Mesencephalon3.66 ± 0.62
Myelencephalon3.68 ± 0.67
Occipital Lobe3.66 ± 0.6
Parietal Lobe3.76 ± 0.69
Pontine Tegmentum3.88 ± 0.72
Striatum3.41 ± 0.73
Subthalamus4.03 ± 0.22
Temporal Lobe3.9 ± 0.58
Thalamus4.06 ± 0.65
White Matter2.12 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gadd45gCBCerebellum20.55
26.58
Gadd45gCTXCerebral cortex25.66
22.35
Gadd45gHIPHippocampal region24.73
29.89
Gadd45gHPFHippocampal formation29.16
33.48
Gadd45gHYHypothalamus11.54
9.61
Gadd45gLSXLateral septal complex26.48
25.48
Gadd45gMBMidbrain7.87
8.8
Gadd45gMYMedulla25.45
30.92
Gadd45gOLFOlfactory bulb49.64
47.81
Gadd45gPPons13.44
14.55
Gadd45gPALPallidum8
7.71
Gadd45gRHPRetrohippocampal region34.48
36.05
Gadd45gsAMYStriatum-like amygdalar nuclei18.32
16.11
Gadd45gSTRStriatum18.47
16.99
Gadd45gSTRdStriatum dorsal region13.23
12.06
Gadd45gSTRvStriatum ventral region30.45
26.55
Gadd45gTHThalamus28.61
24.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
GA45G_HUMAN_1 7 1 7 MTLEEVR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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