AutismKB 2.0

Annotation Detail for RNPS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:RNPS1 ( E5.1,MGC117332 )
Gene Full Name: RNA binding protein S1, serine-rich domain
Band: 16p13.3
Quick LinksEntrez ID:10921; OMIM: 606447; Uniprot ID:RNPS1_HUMAN; ENSEMBL ID: ENSG00000205937; HGNC ID: 10080
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst3 / 6231948
fetus59 / 564012104
neonate1 / 3109732
infant4 / 23620169
juvenile13 / 55556233
adult279 / 1939121143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma2 / 17475114
breast (mammary gland) tumor17 / 94178180
cervical tumor9 / 34366261
chondrosarcoma13 / 82823156
colorectal tumor16 / 114246140
esophageal tumor1 / 1729057
gastrointestinal tumor31 / 119369259
germ cell tumor53 / 263845200
glioma22 / 106883205
head and neck tumor31 / 136302227
kidney tumor7 / 68959101
leukemia13 / 95842135
liver tumor7 / 9635972
lung tumor17 / 103127164
lymphoma7 / 7175597
non-neoplasia5 / 9725051
normal315 / 336030793
ovarian tumor13 / 76682169
pancreatic tumor17 / 104616162
primitive neuroectodermal tumor of the CNS30 / 125680238
prostate cancer30 / 102680292
retinoblastoma6 / 46356129
skin tumor16 / 124949128
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland4 / 33197120
ascites11 / 40015274
bladder1 / 2975733
blood12 / 12347897
bone14 / 71655195
bone marrow2 / 4880140
brain123 / 1100989111
cervix10 / 48171207
connective tissue11 / 14925573
ear3 / 16212185
embryonic tissue26 / 215722120
esophagus1 / 2020949
eye25 / 211054118
heart8 / 8962689
intestine35 / 234472149
kidney17 / 21177780
larynx18 / 24145745
liver16 / 20774377
lung47 / 336974139
lymph2 / 4427045
lymph node9 / 9161098
mammary gland24 / 153271156
mouth3 / 6705244
muscle10 / 10771592
nerve1 / 1576863
ovary21 / 102051205
pancreas32 / 214812148
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland1 / 1658560
placenta37 / 280825131
prostate42 / 189345221
salivary gland6 / 20155297
skin28 / 210574132
spleen3 / 5395255
stomach21 / 96619217
testis37 / 330442111
thymus4 / 8113149
thyroid2 / 4747342
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord0 / 136800 
uterus22 / 23287894
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200060_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1782.05
Adipocyte262.15
AdrenalCortex293.95
Adrenalgland365.3
Amygdala1185.25
Appendix134.85
AtrioventricularNode104.9
BDCA4+_DentriticCells849.6
Bonemarrow477.2
BronchialEpithelialCells679.6
CD105+_Endothelial981.5
CD14+_Monocytes646.25
CD19+_BCells(neg._sel.)1115.05
CD33+_Myeloid773.85
CD34+1176.2
CD4+_Tcells841.1
CD56+_NKCells1021.3
CD71+_EarlyErythroid837.3
CD8+_Tcells770.15
CardiacMyocytes350.95
Caudatenucleus326.05
Cerebellum640.5
CerebellumPeduncles729.4
CiliaryGanglion106.1
CingulateCortex539.05
Colorectaladenocarcinoma882.7
DorsalRootGanglion116.55
FetalThyroid500.15
Fetalbrain717.5
Fetalliver351.25
Fetallung443.85
GlobusPallidus217.4
Heart543.55
Hypothalamus645.35
Kidney214.55
Leukemia_chronicMyelogenousK-562715
Leukemia_promyelocytic-HL-60819.65
Leukemialymphoblastic(MOLT-4)781.4
Liver314.1
Lung958.9
Lymphnode479.65
Lymphoma_burkitts(Daudi)903.35
Lymphoma_burkitts(Raji)1055.9
MedullaOblongata404.75
OccipitalLobe544.85
OlfactoryBulb335.85
Ovary167.8
Pancreas335.3
PancreaticIslet468.5
ParietalLobe398.05
Pituitary572.65
Placenta557.45
Pons255.55
PrefrontalCortex1046.9
Prostate1462.8
Salivarygland291.3
SkeletalMuscle191.55
Skin140.7
SmoothMuscle467.85
Spinalcord414.85
SubthalamicNucleus335.35
SuperiorCervicalGanglion80.7
TemporalLobe357.5
Testis1061.4
TestisGermCell742.7
TestisIntersitial498.75
TestisLeydigCell428.3
TestisSeminiferousTubule614.7
Thalamus447.9
Thymus766.05
Thyroid1047.65
Tongue277.3
Tonsil448.6
Trachea300.65
TrigeminalGanglion95.4
Uterus621.5
UterusCorpus183.8
WholeBlood551.9
Wholebrain1022.25
colon544.65
pineal_day703.84
pineal_night755.28
retina647.775
small_intestine462.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P725630
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.03 ± 0.34
Basal Forebrain9.62 ± 0.3
Basal Part of Pons9.74 ± 0.33
Cerebellar Cortex9.45 ± 0.28
Cerebellar Nuclei9.5 ± 0.4
Claustrum10.31 ± 0.46
Epithalamus8.76 ± 0.53
Frontal Lobe9.56 ± 0.39
Globus Pallidus9.66 ± 0.26
Hypothalamus9.43 ± 0.34
Insula9.7 ± 0.43
Limbic Lobe9.94 ± 0.36
Mesencephalon9.67 ± 0.38
Myelencephalon9.62 ± 0.38
Occipital Lobe9.92 ± 0.41
Parietal Lobe9.74 ± 0.43
Pontine Tegmentum9.57 ± 0.3
Striatum9.51 ± 0.41
Subthalamus9.64 ± 0.15
Temporal Lobe9.65 ± 0.37
Thalamus9.57 ± 0.24
White Matter9.39 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rnps1CBCerebellum8.26
10.03
Rnps1CTXCerebral cortex14.32
11.95
Rnps1HIPHippocampal region24.14
30.04
Rnps1HPFHippocampal formation22.37
25.14
Rnps1HYHypothalamus11.72
10.48
Rnps1LSXLateral septal complex1.02
0.97
Rnps1MBMidbrain2.2
3.35
Rnps1MYMedulla6.25
9.36
Rnps1OLFOlfactory bulb30.31
28.07
Rnps1PPons9.26
12.17
Rnps1PALPallidum4.75
4.96
Rnps1RHPRetrohippocampal region18.82
16.9
Rnps1sAMYStriatum-like amygdalar nuclei8.15
6.14
Rnps1STRStriatum2.54
2.17
Rnps1STRdStriatum dorsal region0.67
0.76
Rnps1STRvStriatum ventral region7.03
5.38
Rnps1THThalamus2.06
2.14
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064925 12 175 186 DHIMEIFSTYGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved