AutismKB 2.0

Annotation Detail for FASTK


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Basic Information Top
Gene Symbol:FASTK ( FAST )
Gene Full Name: Fas-activated serine/threonine kinase
Band: 7q36.1
Quick LinksEntrez ID:10922; OMIM: 606965; Uniprot ID:FASTK_HUMAN; ENSEMBL ID: ENSG00000164896; HGNC ID: 24676
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst5 / 6231980
fetus36 / 56401263
neonate1 / 3109732
infant3 / 23620127
juvenile1 / 5555617
adult161 / 193912183
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor4 / 34366116
chondrosarcoma9 / 82823108
colorectal tumor7 / 11424661
esophageal tumor3 / 17290173
gastrointestinal tumor18 / 119369150
germ cell tumor16 / 26384560
glioma17 / 106883159
head and neck tumor9 / 13630266
kidney tumor14 / 68959203
leukemia7 / 9584273
liver tumor8 / 9635983
lung tumor11 / 103127106
lymphoma14 / 71755195
non-neoplasia9 / 9725092
normal322 / 336030795
ovarian tumor8 / 76682104
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS24 / 125680190
prostate cancer14 / 102680136
retinoblastoma0 / 463560 
skin tumor18 / 124949144
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland5 / 33197150
ascites11 / 40015274
bladder2 / 2975767
blood12 / 12347897
bone4 / 7165555
bone marrow4 / 4880181
brain144 / 1100989130
cervix11 / 48171228
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus3 / 20209148
eye16 / 21105475
heart12 / 89626133
intestine26 / 234472110
kidney27 / 211777127
larynx0 / 241450 
liver10 / 20774348
lung27 / 33697480
lymph6 / 44270135
lymph node9 / 9161098
mammary gland8 / 15327152
mouth2 / 6705229
muscle6 / 10771555
nerve3 / 15768190
ovary13 / 102051127
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta18 / 28082564
prostate24 / 189345126
salivary gland5 / 20155248
skin19 / 21057490
spleen5 / 5395292
stomach7 / 9661972
testis34 / 330442102
thymus12 / 81131147
thyroid4 / 4747384
tonsil6 / 16999352
trachea2 / 5241338
umbilical cord1 / 1368073
uterus29 / 232878124
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 210975_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts154.7
Adipocyte66.05
AdrenalCortex69.15
Adrenalgland64.65
Amygdala74.05
Appendix55.6
AtrioventricularNode39.3
BDCA4+_DentriticCells109.1
Bonemarrow62.25
BronchialEpithelialCells61.15
CD105+_Endothelial77.8
CD14+_Monocytes73.45
CD19+_BCells(neg._sel.)98.85
CD33+_Myeloid83.2
CD34+109.3
CD4+_Tcells161.8
CD56+_NKCells77.45
CD71+_EarlyErythroid106.4
CD8+_Tcells136.9
CardiacMyocytes82.35
Caudatenucleus68.25
Cerebellum68.55
CerebellumPeduncles74.95
CiliaryGanglion36.85
CingulateCortex78.3
Colorectaladenocarcinoma65.5
DorsalRootGanglion41.1
FetalThyroid82.6
Fetalbrain66.7
Fetalliver57.15
Fetallung55.9
GlobusPallidus48.5
Heart311.05
Hypothalamus84.2
Kidney55.95
Leukemia_chronicMyelogenousK-56260.15
Leukemia_promyelocytic-HL-6058.35
Leukemialymphoblastic(MOLT-4)106
Liver100.65
Lung142.3
Lymphnode73.9
Lymphoma_burkitts(Daudi)83.7
Lymphoma_burkitts(Raji)108.5
MedullaOblongata58.3
OccipitalLobe58.25
OlfactoryBulb52.1
Ovary40
Pancreas53.25
PancreaticIslet70.8
ParietalLobe69.25
Pituitary102.2
Placenta64.05
Pons59.3
PrefrontalCortex83.9
Prostate87.75
Salivarygland52.35
SkeletalMuscle97.05
Skin42.15
SmoothMuscle77.15
Spinalcord73.5
SubthalamicNucleus56.7
SuperiorCervicalGanglion61.55
TemporalLobe60.7
Testis59.5
TestisGermCell53.75
TestisIntersitial44
TestisLeydigCell60.15
TestisSeminiferousTubule56.2
Thalamus67.4
Thymus56.4
Thyroid130.4
Tongue72.1
Tonsil64.95
Trachea55.45
TrigeminalGanglion59.1
Uterus88.2
UterusCorpus57.55
WholeBlood58.8
Wholebrain94.35
colon64.35
pineal_day91.02
pineal_night78.72
retina78.95
small_intestine62.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P215140
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.57 ± 0.26
Basal Forebrain8.44 ± 0.19
Basal Part of Pons8.88 ± 0.17
Cerebellar Cortex8.71 ± 0.29
Cerebellar Nuclei8.54 ± 0.43
Claustrum8.8 ± 0.21
Epithalamus8.36 ± 0.29
Frontal Lobe8.55 ± 0.27
Globus Pallidus8.19 ± 0.14
Hypothalamus8.31 ± 0.26
Insula8.48 ± 0.32
Limbic Lobe8.64 ± 0.27
Mesencephalon8.48 ± 0.18
Myelencephalon8.62 ± 0.3
Occipital Lobe8.78 ± 0.31
Parietal Lobe8.58 ± 0.21
Pontine Tegmentum8.5 ± 0.24
Striatum8.74 ± 0.24
Subthalamus8.64 ± 0.22
Temporal Lobe8.62 ± 0.24
Thalamus8.71 ± 0.27
White Matter8.19 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
FastkCBCerebellum49.28
74.47
FastkCTXCerebral cortex100
100
FastkHIPHippocampal region73.92
100
FastkHPFHippocampal formation89.02
100
FastkHYHypothalamus99.52
88.41
FastkLSXLateral septal complex100
93.85
FastkMBMidbrain96.17
97.68
FastkMYMedulla95.19
100
FastkOLFOlfactory bulb100
100
FastkPPons91.5
100
FastkPALPallidum89.54
91.61
FastkRHPRetrohippocampal region100
100
FastksAMYStriatum-like amygdalar nuclei89.62
74.26
FastkSTRStriatum100
90.56
FastkSTRdStriatum dorsal region100
87.29
FastkSTRvStriatum ventral region100
100
FastkTHThalamus100
98.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
FASTK_HUMAN_0 0 0 0 YSHKDIVAEGLRQLLGEEK PRIDE
FASTK_HUMAN_535 9 535 543 QKLQALGLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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