AutismKB 2.0

Annotation Detail for SUB1


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Basic Information Top
Gene Symbol:SUB1 ( MGC102747,P15,PC4,p14 )
Gene Full Name: SUB1 homolog (S. cerevisiae)
Band: 5p13.3
Quick LinksEntrez ID:10923; OMIM: 600503; Uniprot ID:TCP4_HUMAN; ENSEMBL ID: ENSG00000113387; HGNC ID: 19985
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus122 / 564012216
neonate1 / 3109732
infant4 / 23620169
juvenile5 / 5555689
adult363 / 1939121187
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma6 / 17475343
breast (mammary gland) tumor24 / 94178254
cervical tumor6 / 34366174
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor10 / 11936983
germ cell tumor40 / 263845151
glioma4 / 10688337
head and neck tumor43 / 136302315
kidney tumor17 / 68959246
leukemia30 / 95842313
liver tumor13 / 96359134
lung tumor12 / 103127116
lymphoma3 / 7175541
non-neoplasia7 / 9725071
normal693 / 3360307206
ovarian tumor5 / 7668265
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer20 / 102680194
retinoblastoma5 / 46356107
skin tumor8 / 12494964
soft tissue/muscle tissue tumor37 / 125191295
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland8 / 33197240
ascites4 / 4001599
bladder9 / 29757302
blood24 / 123478194
bone9 / 71655125
bone marrow21 / 48801430
brain422 / 1100989383
cervix10 / 48171207
connective tissue31 / 149255207
ear9 / 16212555
embryonic tissue32 / 215722148
esophagus1 / 2020949
eye24 / 211054113
heart15 / 89626167
intestine14 / 23447259
kidney35 / 211777165
larynx5 / 24145207
liver39 / 207743187
lung23 / 33697468
lymph0 / 442700 
lymph node13 / 91610141
mammary gland32 / 153271208
mouth36 / 67052536
muscle21 / 107715194
nerve0 / 157680 
ovary9 / 10205188
pancreas34 / 214812158
parathyroid5 / 20539243
pharynx8 / 41328193
pituitary gland2 / 16585120
placenta47 / 280825167
prostate27 / 189345142
salivary gland35 / 201551736
skin17 / 21057480
spleen4 / 5395274
stomach4 / 9661941
testis53 / 330442160
thymus9 / 81131110
thyroid2 / 4747342
tonsil0 / 169990 
trachea19 / 52413362
umbilical cord0 / 136800 
uterus49 / 232878210
vascular14 / 51780270
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212857_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts3064.6
Adipocyte637.8
AdrenalCortex289.7
Adrenalgland262.85
Amygdala1395.75
Appendix152.45
AtrioventricularNode71.95
BDCA4+_DentriticCells2223.6
Bonemarrow375.15
BronchialEpithelialCells1209.2
CD105+_Endothelial1764.55
CD14+_Monocytes1239.8
CD19+_BCells(neg._sel.)1691.25
CD33+_Myeloid1553.15
CD34+1648.4
CD4+_Tcells1238.25
CD56+_NKCells1734.3
CD71+_EarlyErythroid693.7
CD8+_Tcells1015.85
CardiacMyocytes407.8
Caudatenucleus363.5
Cerebellum157.35
CerebellumPeduncles103.8
CiliaryGanglion115.3
CingulateCortex300.9
Colorectaladenocarcinoma453.95
DorsalRootGanglion94.8
FetalThyroid268.45
Fetalbrain1040.5
Fetalliver717.3
Fetallung636.3
GlobusPallidus163.55
Heart102.35
Hypothalamus608.95
Kidney173.3
Leukemia_chronicMyelogenousK-5621155.65
Leukemia_promyelocytic-HL-601016.75
Leukemialymphoblastic(MOLT-4)1202.65
Liver67.6
Lung167.8
Lymphnode858.8
Lymphoma_burkitts(Daudi)347.45
Lymphoma_burkitts(Raji)962.5
MedullaOblongata273.3
OccipitalLobe518.1
OlfactoryBulb212.25
Ovary138.8
Pancreas331.75
PancreaticIslet503.1
ParietalLobe347.75
Pituitary663.15
Placenta425.05
Pons133.85
PrefrontalCortex658.65
Prostate585
Salivarygland475.15
SkeletalMuscle44.1
Skin104.3
SmoothMuscle717.25
Spinalcord490.35
SubthalamicNucleus240.35
SuperiorCervicalGanglion158.5
TemporalLobe327.8
Testis185.45
TestisGermCell433.45
TestisIntersitial283
TestisLeydigCell204.8
TestisSeminiferousTubule282.35
Thalamus253.05
Thymus412.9
Thyroid1155.1
Tongue229.05
Tonsil784.6
Trachea388.4
TrigeminalGanglion101.1
Uterus784.05
UterusCorpus122.65
WholeBlood1307.6
Wholebrain506.6
colon1304.15
pineal_day706.9
pineal_night785.26
retina357.525
small_intestine923.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P170444
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.78 ± 0.49
Basal Forebrain9.43 ± 0.2
Basal Part of Pons9.4 ± 0.4
Cerebellar Cortex9.4 ± 0.2
Cerebellar Nuclei9.1 ± 0.43
Claustrum9.89 ± 0.24
Epithalamus9.07 ± 0.5
Frontal Lobe9.92 ± 0.32
Globus Pallidus8.37 ± 0.66
Hypothalamus9.96 ± 0.35
Insula10.01 ± 0.36
Limbic Lobe9.81 ± 0.65
Mesencephalon9.54 ± 0.54
Myelencephalon9.51 ± 0.55
Occipital Lobe9.09 ± 0.66
Parietal Lobe9.68 ± 0.48
Pontine Tegmentum9.66 ± 0.63
Striatum9.24 ± 0.72
Subthalamus9.73 ± 0.22
Temporal Lobe9.83 ± 0.33
Thalamus9.47 ± 0.46
White Matter7.62 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Sub1CBCerebellum37.46
96.15
Sub1CTXCerebral cortex100
100
Sub1HIPHippocampal region100
100
Sub1HPFHippocampal formation100
100
Sub1HYHypothalamus89.65
95.81
Sub1LSXLateral septal complex100
100
Sub1MBMidbrain78.43
83.32
Sub1MYMedulla83.71
100
Sub1OLFOlfactory bulb100
100
Sub1PPons72.18
90.09
Sub1PALPallidum85.73
93.43
Sub1RHPRetrohippocampal region100
100
Sub1sAMYStriatum-like amygdalar nuclei99.66
100
Sub1STRStriatum100
100
Sub1STRdStriatum dorsal region100
100
Sub1STRvStriatum ventral region100
100
Sub1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00032888 9 60 68 DDNMFQIGK Peptide Atlas
TCP4_HUMAN_0 0 0 0 DDNMFQIGK PRIDE
TCP4_HUMAN_0 0 0 0 ELVSSSSSGSDSDSEVDKK PRIDE
TCP4_HUMAN_0 0 0 0 EQISDIDDAVR PRIDE
TCP4_HUMAN_0 0 0 0 GISLNPEQWSQLK PRIDE
TCP4_HUMAN_1 26 1 26 PKSKELVSSSSSGSDSDSEVDKKLKR PRIDE
TCP4_HUMAN_100 25 100 124 KGISLNPEQWSQLKEQISDIDDAVR PRIDE
TCP4_HUMAN_101 13 101 113 GISLNPEQWSQLK PRIDE
TCP4_HUMAN_101 24 101 124 GISLNPEQWSQLKEQISDIDDAVR PRIDE
TCP4_HUMAN_114 11 114 124 EQISDIDDAVR PRIDE
TCP4_HUMAN_29 9 29 37 QVAPEKPVK PRIDE
TCP4_HUMAN_59 9 59 67 DDNMFQIGK PRIDE
TCP4_HUMAN_60 10 60 69 DNMFQIGKMR PRIDE
TCP4_HUMAN_86 14 86 99 EYWMDPEGEMKPGR PRIDE
TCP4_HUMAN_86 15 86 100 EYWMDPEGEMKPGRK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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