AutismKB 2.0

Annotation Detail for UGT2A1


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Basic Information Top
Gene Symbol:UGT2A1 ( - )
Gene Full Name: UDP glucuronosyltransferase 2 family, polypeptide A1
Band: 4q13.3
Quick LinksEntrez ID:10941; OMIM: 604716; Uniprot ID:UD2A1_HUMAN; ENSEMBL ID: ENSG00000173610; HGNC ID: 12542
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult2 / 19391211
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal6 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain2 / 11009891
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207958_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte5.2
AdrenalCortex6.75
Adrenalgland4.65
Amygdala5.4
Appendix8.1
AtrioventricularNode19.1
BDCA4+_DentriticCells5.15
Bonemarrow6.35
BronchialEpithelialCells5.2
CD105+_Endothelial5.4
CD14+_Monocytes7.3
CD19+_BCells(neg._sel.)5.6
CD33+_Myeloid8
CD34+7.1
CD4+_Tcells5.05
CD56+_NKCells6.45
CD71+_EarlyErythroid5.1
CD8+_Tcells4.5
CardiacMyocytes8.15
Caudatenucleus4.7
Cerebellum4.2
CerebellumPeduncles6.7
CiliaryGanglion7.85
CingulateCortex5.5
Colorectaladenocarcinoma5.75
DorsalRootGanglion7.6
FetalThyroid5.55
Fetalbrain5.1
Fetalliver4.75
Fetallung4.25
GlobusPallidus4.25
Heart11.45
Hypothalamus5.6
Kidney5.25
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)4.1
Liver10.15
Lung5.8
Lymphnode4.6
Lymphoma_burkitts(Daudi)6.9
Lymphoma_burkitts(Raji)8.9
MedullaOblongata4.75
OccipitalLobe4.65
OlfactoryBulb4.95
Ovary4.6
Pancreas4.4
PancreaticIslet5.75
ParietalLobe5.7
Pituitary6.55
Placenta5.3
Pons5.4
PrefrontalCortex6
Prostate6.35
Salivarygland4.6
SkeletalMuscle7.85
Skin5.3
SmoothMuscle6.05
Spinalcord5.55
SubthalamicNucleus5.6
SuperiorCervicalGanglion9.75
TemporalLobe5.25
Testis4.55
TestisGermCell4.4
TestisIntersitial4.95
TestisLeydigCell5.85
TestisSeminiferousTubule4.45
Thalamus5.4
Thymus4.1
Thyroid6.55
Tongue5.95
Tonsil5.25
Trachea4.35
TrigeminalGanglion8.35
Uterus4.4
UterusCorpus4.95
WholeBlood5.65
Wholebrain4.45
colon5.25
pineal_day6.02
pineal_night6.16
retina6.45
small_intestine5.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_82_PI416383280
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.5 ± 0.99
Basal Forebrain2.07 ± 0.29
Basal Part of Pons1.69 ± 0.29
Cerebellar Cortex1.83 ± 0.72
Cerebellar Nuclei2.4 ± 0.76
Claustrum2.91 ± 0.81
Epithalamus1.68 ± 0.71
Frontal Lobe1.9 ± 0.62
Globus Pallidus2.52 ± 0.34
Hypothalamus2.41 ± 1.09
Insula2.02 ± 0.51
Limbic Lobe2 ± 0.58
Mesencephalon2.19 ± 0.69
Myelencephalon2.06 ± 0.72
Occipital Lobe2.01 ± 0.59
Parietal Lobe2.03 ± 0.7
Pontine Tegmentum2.05 ± 0.63
Striatum2.2 ± 0.65
Subthalamus2.12 ± 0.62
Temporal Lobe1.94 ± 0.72
Thalamus2.03 ± 0.69
White Matter2.5 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ugt2a1CBCerebellum0.25
0.39
Ugt2a1CTXCerebral cortex0.31
0.36
Ugt2a1HIPHippocampal region0.21
0.26
Ugt2a1HPFHippocampal formation0.23
0.29
Ugt2a1HYHypothalamus0.07
0.03
Ugt2a1LSXLateral septal complex0
0
Ugt2a1MBMidbrain0.21
0.2
Ugt2a1MYMedulla0.12
0.1
Ugt2a1OLFOlfactory bulb0.53
1.13
Ugt2a1PPons0.11
0.19
Ugt2a1PALPallidum0.14
0.27
Ugt2a1RHPRetrohippocampal region0.28
0.33
Ugt2a1sAMYStriatum-like amygdalar nuclei0.11
0.07
Ugt2a1STRStriatum0.13
0.28
Ugt2a1STRdStriatum dorsal region0.17
0.41
Ugt2a1STRvStriatum ventral region0.01
0
Ugt2a1THThalamus0.46
0.16
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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