AutismKB 2.0

Annotation Detail for PDIA5


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PDIA5 ( FLJ30401,PDIR )
Gene Full Name: protein disulfide isomerase family A, member 5
Band: 3q21.1
Quick LinksEntrez ID:10954; OMIM: NA; Uniprot ID:PDIA5_HUMAN; ENSEMBL ID: ENSG00000065485; HGNC ID: 24811
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus41 / 56401272
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma10 / 82823120
colorectal tumor5 / 11424643
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor7 / 26384526
glioma3 / 10688328
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal127 / 336030737
ovarian tumor4 / 7668252
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood6 / 12347848
bone6 / 7165583
bone marrow0 / 488010 
brain12 / 110098910
cervix4 / 4817183
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine7 / 23447229
kidney6 / 21177728
larynx1 / 2414541
liver11 / 20774352
lung9 / 33697426
lymph1 / 4427022
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta32 / 280825113
prostate11 / 18934558
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach4 / 9661941
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203857_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts134.7
Adipocyte151.6
AdrenalCortex97.25
Adrenalgland97.65
Amygdala59.45
Appendix117.05
AtrioventricularNode45.3
BDCA4+_DentriticCells321.05
Bonemarrow151.95
BronchialEpithelialCells275.7
CD105+_Endothelial63.55
CD14+_Monocytes61.95
CD19+_BCells(neg._sel.)47.95
CD33+_Myeloid117.15
CD34+286.55
CD4+_Tcells48.95
CD56+_NKCells28.75
CD71+_EarlyErythroid74
CD8+_Tcells40.95
CardiacMyocytes355.65
Caudatenucleus51.9
Cerebellum46.65
CerebellumPeduncles47.1
CiliaryGanglion50.85
CingulateCortex55.85
Colorectaladenocarcinoma250.3
DorsalRootGanglion46.75
FetalThyroid246.05
Fetalbrain65.65
Fetalliver421.55
Fetallung210.65
GlobusPallidus42.6
Heart80.3
Hypothalamus56.95
Kidney65.9
Leukemia_chronicMyelogenousK-562251.55
Leukemia_promyelocytic-HL-6056.2
Leukemialymphoblastic(MOLT-4)58.35
Liver834.35
Lung449.15
Lymphnode134.65
Lymphoma_burkitts(Daudi)64.75
Lymphoma_burkitts(Raji)105.7
MedullaOblongata49.05
OccipitalLobe45.9
OlfactoryBulb42.05
Ovary109.3
Pancreas148
PancreaticIslet169.15
ParietalLobe79.45
Pituitary184.75
Placenta356.9
Pons54.75
PrefrontalCortex50.95
Prostate455.5
Salivarygland46.3
SkeletalMuscle75
Skin50.25
SmoothMuscle676.7
Spinalcord57.05
SubthalamicNucleus51.4
SuperiorCervicalGanglion113.7
TemporalLobe55.05
Testis170.45
TestisGermCell405.45
TestisIntersitial122.3
TestisLeydigCell178
TestisSeminiferousTubule106.3
Thalamus50.75
Thymus69.5
Thyroid319.45
Tongue61.65
Tonsil99.25
Trachea100.4
TrigeminalGanglion67.7
Uterus112.45
UterusCorpus60.5
WholeBlood68.45
Wholebrain40.4
colon133.5
pineal_day40.82
pineal_night53.42
retina133.4
small_intestine139.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16489_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.1 ± 0.85
Basal Forebrain2.74 ± 0.53
Basal Part of Pons2.3 ± 0.34
Cerebellar Cortex2.31 ± 0.61
Cerebellar Nuclei2.82 ± 0.62
Claustrum3.13 ± 0.67
Epithalamus2.43 ± 0.7
Frontal Lobe2.41 ± 0.74
Globus Pallidus2.87 ± 0.72
Hypothalamus2.5 ± 0.71
Insula2.48 ± 0.62
Limbic Lobe2.71 ± 0.75
Mesencephalon2.79 ± 0.77
Myelencephalon2.67 ± 0.66
Occipital Lobe3.31 ± 0.86
Parietal Lobe2.93 ± 0.66
Pontine Tegmentum2.78 ± 0.7
Striatum2.81 ± 0.74
Subthalamus2.95 ± 0.86
Temporal Lobe2.8 ± 0.62
Thalamus2.44 ± 0.68
White Matter2.53 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pdia5CBCerebellum0.67
0.86
Pdia5CTXCerebral cortex9.81
5.16
Pdia5HIPHippocampal region0.96
0.84
Pdia5HPFHippocampal formation1.69
1
Pdia5HYHypothalamus0.77
0.79
Pdia5LSXLateral septal complex0.21
0.12
Pdia5MBMidbrain1.06
0.97
Pdia5MYMedulla1.35
0.92
Pdia5OLFOlfactory bulb5.18
3.51
Pdia5PPons1.95
2.03
Pdia5PALPallidum0.44
0.44
Pdia5RHPRetrohippocampal region2.48
1.07
Pdia5sAMYStriatum-like amygdalar nuclei0.54
0.37
Pdia5STRStriatum3.87
2.63
Pdia5STRdStriatum dorsal region4.22
3.02
Pdia5STRvStriatum ventral region4.91
2.7
Pdia5THThalamus3.13
1.7
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00002806 10 226 235 GFPTICYFEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved