AutismKB 2.0

Annotation Detail for C10orf116


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Basic Information Top
Gene Symbol:C10orf116 ( APM2 )
Gene Full Name: chromosome 10 open reading frame 116
Band: 10q23.2
Quick LinksEntrez ID:10974; OMIM: NA; Uniprot ID:APM2_HUMAN; ENSEMBL ID: ENSG00000148671; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus7 / 56401212
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor0 / 2638450 
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal106 / 336030731
ovarian tumor12 / 76682156
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain16 / 110098914
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye14 / 21105466
heart4 / 8962644
intestine11 / 23447246
kidney3 / 21177714
larynx1 / 2414541
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth0 / 670520 
muscle12 / 107715111
nerve0 / 157680 
ovary12 / 102051117
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta1 / 2808253
prostate22 / 189345116
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach3 / 9661931
testis5 / 33044215
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203571_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.1
Adipocyte692.45
AdrenalCortex26.05
Adrenalgland46.6
Amygdala50.45
Appendix266.25
AtrioventricularNode141.6
BDCA4+_DentriticCells10.35
Bonemarrow16.25
BronchialEpithelialCells92.15
CD105+_Endothelial11.65
CD14+_Monocytes11.5
CD19+_BCells(neg._sel.)10.3
CD33+_Myeloid13.5
CD34+13.45
CD4+_Tcells12.7
CD56+_NKCells12.75
CD71+_EarlyErythroid11.5
CD8+_Tcells12.45
CardiacMyocytes16.95
Caudatenucleus18.15
Cerebellum11.65
CerebellumPeduncles21.35
CiliaryGanglion204
CingulateCortex19.6
Colorectaladenocarcinoma104.95
DorsalRootGanglion185.55
FetalThyroid193.8
Fetalbrain13.35
Fetalliver12.55
Fetallung36.8
GlobusPallidus12.8
Heart857.55
Hypothalamus90.15
Kidney122.65
Leukemia_chronicMyelogenousK-56212.7
Leukemia_promyelocytic-HL-6013.9
Leukemialymphoblastic(MOLT-4)10.75
Liver139.6
Lung1246.95
Lymphnode60.25
Lymphoma_burkitts(Daudi)18.65
Lymphoma_burkitts(Raji)18.65
MedullaOblongata15.4
OccipitalLobe18.45
OlfactoryBulb203.35
Ovary350.35
Pancreas264
PancreaticIslet45.1
ParietalLobe15.75
Pituitary74.35
Placenta26.95
Pons13.4
PrefrontalCortex70.8
Prostate2450.2
Salivarygland70.25
SkeletalMuscle18.95
Skin134.45
SmoothMuscle18.8
Spinalcord109.5
SubthalamicNucleus14.95
SuperiorCervicalGanglion65.45
TemporalLobe14.85
Testis19.05
TestisGermCell56.45
TestisIntersitial37.65
TestisLeydigCell35.3
TestisSeminiferousTubule42.95
Thalamus47.6
Thymus130.8
Thyroid504.25
Tongue175.35
Tonsil41.1
Trachea114.2
TrigeminalGanglion107.5
Uterus856.7
UterusCorpus75.9
WholeBlood13
Wholebrain56.55
colon125.3
pineal_day54.88
pineal_night29.84
retina528.2
small_intestine539.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12749_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.45 ± 0.37
Basal Forebrain7.02 ± 0.2
Basal Part of Pons6.63 ± 0.42
Cerebellar Cortex6.48 ± 0.29
Cerebellar Nuclei6.96 ± 0.48
Claustrum6.35 ± 0.4
Epithalamus7.95 ± 0.25
Frontal Lobe6.95 ± 0.53
Globus Pallidus7.56 ± 0.31
Hypothalamus7.1 ± 0.8
Insula7.17 ± 0.35
Limbic Lobe7.1 ± 0.6
Mesencephalon7 ± 0.49
Myelencephalon7.08 ± 0.46
Occipital Lobe6.72 ± 0.41
Parietal Lobe6.77 ± 0.53
Pontine Tegmentum7.12 ± 0.46
Striatum7.48 ± 0.31
Subthalamus6.49 ± 0.32
Temporal Lobe7.09 ± 0.47
Thalamus7.07 ± 0.37
White Matter7.31 ± 0.64
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00131379 31 11 41 QQVEGTAQEAVSAAGAAAQQVVDQATEAGQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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