AutismKB 2.0

Annotation Detail for CLP1


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Basic Information Top
Gene Symbol:CLP1 ( HEAB,hClp1 )
Gene Full Name: CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)
Band: 11q12.1
Quick LinksEntrez ID:10978; OMIM: 608757; Uniprot ID:CLP1_HUMAN; ENSEMBL ID: ENSG00000172409; HGNC ID: 16999
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus27 / 56401247
neonate0 / 310970 
infant3 / 23620127
juvenile1 / 5555617
adult42 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor2 / 11424617
esophageal tumor2 / 17290115
gastrointestinal tumor3 / 11936925
germ cell tumor14 / 26384553
glioma6 / 10688356
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal100 / 336030729
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone9 / 71655125
bone marrow1 / 4880120
brain19 / 110098917
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus2 / 2020998
eye6 / 21105428
heart8 / 8962689
intestine13 / 23447255
kidney9 / 21177742
larynx0 / 241450 
liver2 / 2077439
lung12 / 33697435
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary4 / 10205139
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate1 / 1893455
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach2 / 9661920
testis11 / 33044233
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204370_at
Cell line Expression level Expression bar
721_B_lymphoblasts41.9
Adipocyte8.3
AdrenalCortex6.5
Adrenalgland5.2
Amygdala5.25
Appendix13.45
AtrioventricularNode5.3
BDCA4+_DentriticCells44.55
Bonemarrow7.95
BronchialEpithelialCells28.25
CD105+_Endothelial14.4
CD14+_Monocytes9.9
CD19+_BCells(neg._sel.)15.6
CD33+_Myeloid8.2
CD34+12.9
CD4+_Tcells6.85
CD56+_NKCells32.8
CD71+_EarlyErythroid5.9
CD8+_Tcells6.45
CardiacMyocytes8.05
Caudatenucleus5.1
Cerebellum5
CerebellumPeduncles7
CiliaryGanglion4.45
CingulateCortex6.25
Colorectaladenocarcinoma10.9
DorsalRootGanglion4.8
FetalThyroid5.95
Fetalbrain6.2
Fetalliver9.6
Fetallung5.35
GlobusPallidus4.45
Heart7.9
Hypothalamus6.95
Kidney5
Leukemia_chronicMyelogenousK-56219.15
Leukemia_promyelocytic-HL-608.6
Leukemialymphoblastic(MOLT-4)14.9
Liver8.25
Lung10.4
Lymphnode5.5
Lymphoma_burkitts(Daudi)12.7
Lymphoma_burkitts(Raji)9.65
MedullaOblongata7.1
OccipitalLobe5.3
OlfactoryBulb5.95
Ovary5.15
Pancreas5.05
PancreaticIslet7.15
ParietalLobe6.35
Pituitary7.35
Placenta26.65
Pons5.95
PrefrontalCortex7.7
Prostate7.25
Salivarygland4.9
SkeletalMuscle7.25
Skin4.75
SmoothMuscle10.3
Spinalcord6.55
SubthalamicNucleus5
SuperiorCervicalGanglion7.9
TemporalLobe5.4
Testis7.1
TestisGermCell5.95
TestisIntersitial5.65
TestisLeydigCell8.55
TestisSeminiferousTubule6.15
Thalamus5.75
Thymus6.4
Thyroid6.65
Tongue6.05
Tonsil9.5
Trachea5.25
TrigeminalGanglion8.7
Uterus6.35
UterusCorpus7.3
WholeBlood27
Wholebrain5.1
colon6.15
pineal_day7.1
pineal_night6.96
retina7.675
small_intestine5.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P87141
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.14 ± 0.73
Basal Forebrain3.83 ± 0.48
Basal Part of Pons4.21 ± 0.18
Cerebellar Cortex4.53 ± 0.21
Cerebellar Nuclei4.17 ± 0.44
Claustrum3.82 ± 0.83
Epithalamus4.1 ± 0.49
Frontal Lobe4.23 ± 0.46
Globus Pallidus3.3 ± 0.5
Hypothalamus3.93 ± 0.45
Insula4.29 ± 0.27
Limbic Lobe3.99 ± 0.55
Mesencephalon4.15 ± 0.79
Myelencephalon4.02 ± 0.56
Occipital Lobe4.08 ± 0.61
Parietal Lobe4.19 ± 0.62
Pontine Tegmentum4.27 ± 0.32
Striatum3.65 ± 0.61
Subthalamus4.43 ± 0.43
Temporal Lobe4.17 ± 0.42
Thalamus4.19 ± 0.45
White Matter2.87 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
AI462438CBCerebellum15.47
24.08
AI462438CTXCerebral cortex59.31
51.8
AI462438HIPHippocampal region58.41
95.56
AI462438HPFHippocampal formation50.21
68.67
AI462438HYHypothalamus10.57
8.6
AI462438LSXLateral septal complex17.26
12.94
AI462438MBMidbrain14.48
14.62
AI462438MYMedulla9
10.59
AI462438OLFOlfactory bulb41.37
39.8
AI462438PPons17.29
20.59
AI462438PALPallidum12.64
11.42
AI462438RHPRetrohippocampal region36.93
33.34
AI462438sAMYStriatum-like amygdalar nuclei19.24
15.67
AI462438STRStriatum21.53
15.81
AI462438STRdStriatum dorsal region20.19
14.52
AI462438STRvStriatum ventral region28.77
20.32
AI462438THThalamus25.62
21.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CLP1_HUMAN_408 13 408 420 PLPKNFLLIMDIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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