AutismKB 2.0

Annotation Detail for CCNI


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CCNI ( CYC1,CYI )
Gene Full Name: cyclin I
Band: 4q21.1
Quick LinksEntrez ID:10983; OMIM: NA; Uniprot ID:CCNI_HUMAN; ENSEMBL ID: ENSG00000118816; HGNC ID: 1595
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst12 / 62319192
fetus135 / 564012239
neonate8 / 31097257
infant2 / 2362084
juvenile9 / 55556161
adult627 / 1939121323
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma5 / 17475286
breast (mammary gland) tumor26 / 94178276
cervical tumor5 / 34366145
chondrosarcoma14 / 82823169
colorectal tumor25 / 114246218
esophageal tumor1 / 1729057
gastrointestinal tumor17 / 119369142
germ cell tumor53 / 263845200
glioma45 / 106883421
head and neck tumor34 / 136302249
kidney tumor23 / 68959333
leukemia36 / 95842375
liver tumor18 / 96359186
lung tumor26 / 103127252
lymphoma22 / 71755306
non-neoplasia16 / 97250164
normal804 / 3360307239
ovarian tumor49 / 76682639
pancreatic tumor31 / 104616296
primitive neuroectodermal tumor of the CNS31 / 125680246
prostate cancer21 / 102680204
retinoblastoma14 / 46356302
skin tumor20 / 124949160
soft tissue/muscle tissue tumor95 / 125191758
uterine tumor83 / 90257919
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland6 / 33197180
ascites2 / 4001549
bladder8 / 29757268
blood36 / 123478291
bone22 / 71655307
bone marrow15 / 48801307
brain241 / 1100989218
cervix5 / 48171103
connective tissue74 / 149255495
ear35 / 162122158
embryonic tissue55 / 215722254
esophagus2 / 2020998
eye123 / 211054582
heart18 / 89626200
intestine57 / 234472243
kidney58 / 211777273
larynx18 / 24145745
liver27 / 207743129
lung92 / 336974273
lymph18 / 44270406
lymph node28 / 91610305
mammary gland43 / 153271280
mouth6 / 6705289
muscle34 / 107715315
nerve4 / 15768253
ovary54 / 102051529
pancreas68 / 214812316
parathyroid8 / 20539389
pharynx7 / 41328169
pituitary gland1 / 1658560
placenta35 / 280825124
prostate43 / 189345227
salivary gland14 / 20155694
skin46 / 210574218
spleen8 / 53952148
stomach9 / 9661993
testis64 / 330442193
thymus13 / 81131160
thyroid15 / 47473315
tonsil17 / 169991000
trachea2 / 5241338
umbilical cord6 / 13680438
uterus124 / 232878532
vascular22 / 51780424
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208655_at
Cell line Expression level Expression bar
721_B_lymphoblasts1392.85
Adipocyte789.8
AdrenalCortex263.7
Adrenalgland403.95
Amygdala1344.3
Appendix636.25
AtrioventricularNode274.45
BDCA4+_DentriticCells990.8
Bonemarrow776.8
BronchialEpithelialCells1592.9
CD105+_Endothelial623.8
CD14+_Monocytes1784.15
CD19+_BCells(neg._sel.)2537.25
CD33+_Myeloid1326.8
CD34+1211.9
CD4+_Tcells1212.3
CD56+_NKCells1390.55
CD71+_EarlyErythroid1008.2
CD8+_Tcells1117.1
CardiacMyocytes617.9
Caudatenucleus792.95
Cerebellum2731.8
CerebellumPeduncles2758.95
CiliaryGanglion305.85
CingulateCortex1155.15
Colorectaladenocarcinoma984.2
DorsalRootGanglion335.95
FetalThyroid1160.55
Fetalbrain3417.85
Fetalliver450.05
Fetallung801.65
GlobusPallidus1249.2
Heart561.65
Hypothalamus1085
Kidney615.25
Leukemia_chronicMyelogenousK-562458.75
Leukemia_promyelocytic-HL-60908.35
Leukemialymphoblastic(MOLT-4)1094.55
Liver288.65
Lung841
Lymphnode1022.75
Lymphoma_burkitts(Daudi)1266.65
Lymphoma_burkitts(Raji)1583.6
MedullaOblongata1338.95
OccipitalLobe1807.4
OlfactoryBulb810.75
Ovary832
Pancreas555.25
PancreaticIslet1455.6
ParietalLobe1709.9
Pituitary721.25
Placenta916.65
Pons898.25
PrefrontalCortex2270.3
Prostate1544.8
Salivarygland1186.65
SkeletalMuscle77.15
Skin448
SmoothMuscle1175.1
Spinalcord989.45
SubthalamicNucleus1371.7
SuperiorCervicalGanglion177.85
TemporalLobe1188.3
Testis547
TestisGermCell910.9
TestisIntersitial567.55
TestisLeydigCell570
TestisSeminiferousTubule537.85
Thalamus915.9
Thymus1041.25
Thyroid3893.15
Tongue509.2
Tonsil1003.05
Trachea1166.95
TrigeminalGanglion360.7
Uterus1731.1
UterusCorpus669.3
WholeBlood1988.75
Wholebrain1986.2
colon1066.6
pineal_day1432.26
pineal_night1460.5
retina1817
small_intestine1045.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_847_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.45 ± 0.32
Basal Forebrain9.92 ± 0.25
Basal Part of Pons10.38 ± 0.18
Cerebellar Cortex10.21 ± 0.25
Cerebellar Nuclei10.15 ± 0.27
Claustrum10.12 ± 0.34
Epithalamus9.9 ± 0.25
Frontal Lobe9.96 ± 0.4
Globus Pallidus9.55 ± 0.12
Hypothalamus9.53 ± 0.25
Insula9.79 ± 0.37
Limbic Lobe9.59 ± 0.44
Mesencephalon9.81 ± 0.32
Myelencephalon9.83 ± 0.42
Occipital Lobe9.93 ± 0.39
Parietal Lobe10.09 ± 0.35
Pontine Tegmentum9.72 ± 0.25
Striatum9.2 ± 0.33
Subthalamus10.16 ± 0.25
Temporal Lobe9.87 ± 0.36
Thalamus9.98 ± 0.21
White Matter9.51 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
CcniCBCerebellum95.56
100
CcniCTXCerebral cortex100
100
CcniHIPHippocampal region88.08
100
CcniHPFHippocampal formation100
100
CcniHYHypothalamus71.03
52.7
CcniLSXLateral septal complex85.94
60.18
CcniMBMidbrain80.92
75.45
CcniMYMedulla92.49
96.9
CcniOLFOlfactory bulb100
99.3
CcniPPons86.69
92.28
CcniPALPallidum85.49
79.68
CcniRHPRetrohippocampal region100
94.36
CcnisAMYStriatum-like amygdalar nuclei97.2
75.43
CcniSTRStriatum93.59
72.07
CcniSTRdStriatum dorsal region91.61
70.87
CcniSTRvStriatum ventral region98.03
74.06
CcniTHThalamus91.27
80.05
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved