Annotation Detail for RIPK3
Basic Information Top
| Gene Symbol: | RIPK3 ( RIP3 ) |
|---|---|
| Gene Full Name: | receptor-interacting serine-threonine kinase 3 |
| Band: | 14q12 |
| Quick Links | Entrez ID:11035; OMIM: 605817; Uniprot ID:RIPK3_HUMAN; ENSEMBL ID: ENSG00000129465; HGNC ID: 10021 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.268551
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 2 / 564012 | 3 |  |
| neonate | 2 / 31097 | 64 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 58 / 1939121 | 29 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 7 / 94178 | 74 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 1 / 114246 | 8 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 1 / 106883 | 9 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 5 / 95842 | 52 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 17 / 103127 | 164 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 107 / 3360307 | 31 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 5 / 29757 | 168 | |
| blood | 15 / 123478 | 121 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 10 / 1100989 | 9 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 7 / 149255 | 46 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 0 / 211054 | 0 | |
| heart | 3 / 89626 | 33 | |
| intestine | 18 / 234472 | 76 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 1 / 24145 | 41 | |
| liver | 3 / 207743 | 14 | |
| lung | 30 / 336974 | 89 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 4 / 91610 | 43 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 2 / 210574 | 9 | |
| spleen | 19 / 53952 | 352 |  |
| stomach | 2 / 96619 | 20 | |
| testis | 3 / 330442 | 9 | |
| thymus | 5 / 81131 | 61 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: CUST_7890_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.44 ± 1.32 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.97 ± 0.62 | |
| Basal Part of Pons | 2.47 ± 1.04 | |
| Cerebellar Cortex | 2.65 ± 0.69 | |
| Cerebellar Nuclei | 2.69 ± 0.71 | |
| Claustrum | 2.94 ± 0.99 | |
| Epithalamus | 1.54 ± 1.13 | |
| Frontal Lobe | 1.66 ± 0.92 | |
| Globus Pallidus | 3.34 ± 1.05 | |
| Hypothalamus | 1.89 ± 1.28 | |
| Insula | 1.63 ± 0.46 | |
| Limbic Lobe | 1.88 ± 0.85 | |
| Mesencephalon | 1.8 ± 0.97 | |
| Myelencephalon | 1.99 ± 0.9 | |
| Occipital Lobe | 2.32 ± 1.23 | |
| Parietal Lobe | 2.12 ± 1.24 | |
| Pontine Tegmentum | 2.13 ± 1.05 | |
| Striatum | 2.09 ± 1.08 | |
| Subthalamus | 2.43 ± 0.29 | |
| Temporal Lobe | 1.75 ± 1.03 | |
| Thalamus | 2.13 ± 0.87 | |
| White Matter | 2.42 ± 0.61 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ripk3 | CB | Cerebellum | 4.85 | |
| 8.01 | | |||
| Ripk3 | CTX | Cerebral cortex | 13.28 | |
| 10.51 | | |||
| Ripk3 | HIP | Hippocampal region | 6.41 | |
| 6.39 | | |||
| Ripk3 | HPF | Hippocampal formation | 5.72 | |
| 5.52 | | |||
| Ripk3 | HY | Hypothalamus | 21.76 | |
| 17.77 | | |||
| Ripk3 | LSX | Lateral septal complex | 7.67 | |
| 5.66 | | |||
| Ripk3 | MB | Midbrain | 10.13 | |
| 11.05 | | |||
| Ripk3 | MY | Medulla | 4.56 | |
| 4.83 | | |||
| Ripk3 | OLF | Olfactory bulb | 11.09 | |
| 9.68 | | |||
| Ripk3 | P | Pons | 6.16 | |
| 6.82 | | |||
| Ripk3 | PAL | Pallidum | 11.23 | |
| 9.01 | | |||
| Ripk3 | RHP | Retrohippocampal region | 4.25 | |
| 4.1 | | |||
| Ripk3 | sAMY | Striatum-like amygdalar nuclei | 5.72 | |
| 4.7 | | |||
| Ripk3 | STR | Striatum | 16.12 | |
| 12.86 | | |||
| Ripk3 | STRd | Striatum dorsal region | 19.44 | |
| 15.7 | | |||
| Ripk3 | STRv | Striatum ventral region | 16.48 | |
| 13.04 | | |||
| Ripk3 | TH | Thalamus | 16.74 | |
| 13.69 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| RIPK3_HUMAN_0 | 1 | 0 | 0 | AM@ASLDNEFVLRLEGVIEK | PRIDE |