AutismKB 2.0

Annotation Detail for PIM2


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Basic Information Top
Gene Symbol:PIM2 ( - )
Gene Full Name: pim-2 oncogene
Band: Xp11.23
Quick LinksEntrez ID:11040; OMIM: 300295; Uniprot ID:PIM2_HUMAN; ENSEMBL ID: ENSG00000102096; HGNC ID: 8987
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst8 / 62319128
fetus8 / 56401214
neonate2 / 3109764
infant0 / 236200 
juvenile3 / 5555653
adult113 / 193912158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor37 / 263845140
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor1 / 6895914
leukemia12 / 95842125
liver tumor4 / 9635941
lung tumor10 / 10312796
lymphoma6 / 7175583
non-neoplasia15 / 97250154
normal206 / 336030761
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder0 / 297570 
blood54 / 123478437
bone1 / 7165513
bone marrow8 / 48801163
brain73 / 110098966
cervix3 / 4817162
connective tissue17 / 149255113
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus2 / 2020998
eye2 / 2110549
heart3 / 8962633
intestine18 / 23447276
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung14 / 33697441
lymph6 / 44270135
lymph node1 / 9161010
mammary gland3 / 15327119
mouth7 / 67052104
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen17 / 53952315
stomach5 / 9661951
testis31 / 33044293
thymus18 / 81131221
thyroid0 / 474730 
tonsil2 / 16999117
trachea3 / 5241357
umbilical cord0 / 136800 
uterus14 / 23287860
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204269_at
Cell line Expression level Expression bar
721_B_lymphoblasts37.45
Adipocyte23.45
AdrenalCortex25.65
Adrenalgland20.5
Amygdala20.35
Appendix23.7
AtrioventricularNode17.75
BDCA4+_DentriticCells160.75
Bonemarrow35.5
BronchialEpithelialCells22.75
CD105+_Endothelial26.3
CD14+_Monocytes25.4
CD19+_BCells(neg._sel.)121.25
CD33+_Myeloid30.6
CD34+29.95
CD4+_Tcells175.1
CD56+_NKCells76.7
CD71+_EarlyErythroid31.6
CD8+_Tcells221.3
CardiacMyocytes28.45
Caudatenucleus21.2
Cerebellum19.75
CerebellumPeduncles33.9
CiliaryGanglion18.75
CingulateCortex24.1
Colorectaladenocarcinoma23.8
DorsalRootGanglion20.05
FetalThyroid23.05
Fetalbrain23.6
Fetalliver21.1
Fetallung20.15
GlobusPallidus17.3
Heart31.35
Hypothalamus23.9
Kidney20.2
Leukemia_chronicMyelogenousK-562246.9
Leukemia_promyelocytic-HL-60160
Leukemialymphoblastic(MOLT-4)18.6
Liver33
Lung25.3
Lymphnode103.1
Lymphoma_burkitts(Daudi)156.05
Lymphoma_burkitts(Raji)132.05
MedullaOblongata20.85
OccipitalLobe21.05
OlfactoryBulb18.75
Ovary15.65
Pancreas21.25
PancreaticIslet25.75
ParietalLobe25.9
Pituitary32.85
Placenta20.85
Pons22.9
PrefrontalCortex28.5
Prostate24.25
Salivarygland19.1
SkeletalMuscle41.4
Skin17.95
SmoothMuscle22.7
Spinalcord23.65
SubthalamicNucleus22.7
SuperiorCervicalGanglion27.9
TemporalLobe21.55
Testis20.8
TestisGermCell18.35
TestisIntersitial19.45
TestisLeydigCell23.4
TestisSeminiferousTubule20.4
Thalamus25.7
Thymus26.05
Thyroid27.9
Tongue22.85
Tonsil71.15
Trachea35
TrigeminalGanglion23.2
Uterus17.2
UterusCorpus21.25
WholeBlood129.05
Wholebrain20.55
colon23.45
pineal_day27.58
pineal_night28.22
retina28.025
small_intestine22.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P379104
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.75 ± 0.67
Basal Forebrain5.81 ± 0.52
Basal Part of Pons6.21 ± 0.36
Cerebellar Cortex6.11 ± 0.44
Cerebellar Nuclei5.25 ± 0.61
Claustrum5.85 ± 0.43
Epithalamus6.14 ± 0.63
Frontal Lobe6.1 ± 0.47
Globus Pallidus4.41 ± 0.56
Hypothalamus6.17 ± 0.37
Insula6.34 ± 0.35
Limbic Lobe6.19 ± 0.59
Mesencephalon5.7 ± 0.58
Myelencephalon5.83 ± 0.7
Occipital Lobe5.29 ± 0.62
Parietal Lobe5.69 ± 0.48
Pontine Tegmentum5.82 ± 0.6
Striatum5.54 ± 0.61
Subthalamus6.34 ± 1.11
Temporal Lobe6.14 ± 0.52
Thalamus5.64 ± 0.46
White Matter3.54 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pim2CBCerebellum0
0
Pim2CTXCerebral cortex0
0
Pim2HIPHippocampal region0
0
Pim2HPFHippocampal formation0
0
Pim2HYHypothalamus0
0
Pim2LSXLateral septal complex0
0
Pim2MBMidbrain0
0
Pim2MYMedulla0
0
Pim2OLFOlfactory bulb0
0
Pim2PPons0
0
Pim2PALPallidum0
0
Pim2RHPRetrohippocampal region0
0
Pim2sAMYStriatum-like amygdalar nuclei0
0
Pim2STRStriatum0
0
Pim2STRdStriatum dorsal region0
0
Pim2STRvStriatum ventral region0
0
Pim2THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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