AutismKB 2.0

Annotation Detail for OGFR


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Basic Information Top
Gene Symbol:OGFR ( - )
Gene Full Name: opioid growth factor receptor
Band: 20q13.33
Quick LinksEntrez ID:11054; OMIM: 606459; Uniprot ID:OGFR_HUMAN; ENSEMBL ID: ENSG00000060491; HGNC ID: 15768
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult107 / 193912155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor3 / 17290173
gastrointestinal tumor7 / 11936958
germ cell tumor25 / 26384594
glioma10 / 10688393
head and neck tumor1 / 1363027
kidney tumor3 / 6895943
leukemia6 / 9584262
liver tumor6 / 9635962
lung tumor16 / 103127155
lymphoma5 / 7175569
non-neoplasia3 / 9725030
normal149 / 336030744
ovarian tumor6 / 7668278
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor31 / 124949248
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder2 / 2975767
blood12 / 12347897
bone7 / 7165597
bone marrow2 / 4880140
brain46 / 110098941
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus3 / 20209148
eye14 / 21105466
heart0 / 896260 
intestine14 / 23447259
kidney4 / 21177718
larynx0 / 241450 
liver8 / 20774338
lung23 / 33697468
lymph4 / 4427090
lymph node2 / 9161021
mammary gland11 / 15327171
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary10 / 10205197
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta12 / 28082542
prostate6 / 18934531
salivary gland1 / 2015549
skin34 / 210574161
spleen2 / 5395237
stomach5 / 9661951
testis14 / 33044242
thymus5 / 8113161
thyroid4 / 4747384
tonsil2 / 16999117
trachea2 / 5241338
umbilical cord0 / 136800 
uterus18 / 23287877
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211513_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts14.25
Adipocyte5.75
AdrenalCortex6
Adrenalgland4.9
Amygdala6.1
Appendix5.9
AtrioventricularNode4.6
BDCA4+_DentriticCells25.8
Bonemarrow5.75
BronchialEpithelialCells5.6
CD105+_Endothelial5.95
CD14+_Monocytes14.3
CD19+_BCells(neg._sel.)8.25
CD33+_Myeloid18.9
CD34+8.15
CD4+_Tcells11.6
CD56+_NKCells10.5
CD71+_EarlyErythroid5.6
CD8+_Tcells6.55
CardiacMyocytes7.1
Caudatenucleus5.15
Cerebellum4.85
CerebellumPeduncles6.65
CiliaryGanglion4.3
CingulateCortex5.95
Colorectaladenocarcinoma5.7
DorsalRootGanglion4.75
FetalThyroid5.6
Fetalbrain5.85
Fetalliver4.95
Fetallung4.65
GlobusPallidus4.3
Heart7.35
Hypothalamus6.3
Kidney4.65
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.15
Leukemialymphoblastic(MOLT-4)4.7
Liver7.75
Lung6.5
Lymphnode5.05
Lymphoma_burkitts(Daudi)7.4
Lymphoma_burkitts(Raji)8.5
MedullaOblongata5.15
OccipitalLobe5.25
OlfactoryBulb4.6
Ovary3.85
Pancreas4.65
PancreaticIslet6.2
ParietalLobe6.1
Pituitary6.75
Placenta5.75
Pons5.55
PrefrontalCortex6.95
Prostate6.95
Salivarygland4.6
SkeletalMuscle6.9
Skin4.6
SmoothMuscle6.5
Spinalcord6.2
SubthalamicNucleus5.3
SuperiorCervicalGanglion6.5
TemporalLobe5.3
Testis4.9
TestisGermCell4.25
TestisIntersitial4.75
TestisLeydigCell5.7
TestisSeminiferousTubule4.95
Thalamus5.9
Thymus4.55
Thyroid7.35
Tongue5.75
Tonsil5.65
Trachea4.6
TrigeminalGanglion6.2
Uterus4.45
UterusCorpus5.2
WholeBlood6.45
Wholebrain5
colon5.7
pineal_day7.36
pineal_night7.24
retina7.075
small_intestine5.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12998_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.8 ± 0.94
Basal Forebrain2.16 ± 0.2
Basal Part of Pons2.29 ± 0.6
Cerebellar Cortex2.42 ± 0.63
Cerebellar Nuclei2.5 ± 0.64
Claustrum2.87 ± 0.71
Epithalamus2.19 ± 0.55
Frontal Lobe2.47 ± 0.65
Globus Pallidus1.97 ± 0.51
Hypothalamus2.3 ± 0.52
Insula2.43 ± 0.87
Limbic Lobe2.42 ± 0.64
Mesencephalon2.57 ± 0.75
Myelencephalon2.46 ± 0.68
Occipital Lobe2.4 ± 0.72
Parietal Lobe2.59 ± 0.67
Pontine Tegmentum2.46 ± 0.66
Striatum2 ± 0.71
Subthalamus2.48 ± 0.67
Temporal Lobe2.59 ± 0.7
Thalamus2.34 ± 0.68
White Matter1.87 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
OgfrCBCerebellum51.92
100
OgfrCTXCerebral cortex100
100
OgfrHIPHippocampal region97.12
100
OgfrHPFHippocampal formation100
100
OgfrHYHypothalamus62.4
62.47
OgfrLSXLateral septal complex83.93
78.84
OgfrMBMidbrain76.36
88.95
OgfrMYMedulla73.23
100
OgfrOLFOlfactory bulb100
100
OgfrPPons64
86.66
OgfrPALPallidum52.45
60.72
OgfrRHPRetrohippocampal region100
100
OgfrsAMYStriatum-like amygdalar nuclei69.38
64.78
OgfrSTRStriatum63.17
55.99
OgfrSTRdStriatum dorsal region62.67
53.81
OgfrSTRvStriatum ventral region55.51
50.88
OgfrTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
OGFR_HUMAN_391 18 391 408 REQPPTEPGPQSASEVEK PRIDE
OGFR_HUMAN_546 20 546 565 PAGPAGDEPAESPSETPGPR PRIDE
OGFR_HUMAN_626 26 626 651 PAGPAGDEPAESPSETPGPSPAGPTR PRIDE
PAp00007732 25 426 450 TGTQEVGGQDPGEAVQPCRQPLGAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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