AutismKB 2.0

Annotation Detail for TRIOBP


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Basic Information Top
Gene Symbol:TRIOBP ( DFNB28,FLJ39315,KIAA1662,TARA,dJ37E16.4 )
Gene Full Name: TRIO and F-actin binding protein
Band: 22q13.1
Quick LinksEntrez ID:11078; OMIM: 609761; Uniprot ID:TARA_HUMAN; ENSEMBL ID: ENSG00000100101,ENSG00000100106; HGNC ID: 17009
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body10 / 70761141
blastocyst4 / 6231964
fetus29 / 56401251
neonate0 / 310970 
infant1 / 2362042
juvenile3 / 5555653
adult143 / 193912173
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor9 / 9417895
cervical tumor4 / 34366116
chondrosarcoma8 / 8282396
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor32 / 263845121
glioma15 / 106883140
head and neck tumor38 / 136302278
kidney tumor14 / 68959203
leukemia6 / 9584262
liver tumor12 / 96359124
lung tumor17 / 103127164
lymphoma6 / 7175583
non-neoplasia1 / 9725010
normal211 / 336030762
ovarian tumor5 / 7668265
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer3 / 10268029
retinoblastoma4 / 4635686
skin tumor39 / 124949312
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood7 / 12347856
bone4 / 7165555
bone marrow1 / 4880120
brain45 / 110098940
cervix3 / 4817162
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye38 / 211054180
heart8 / 8962689
intestine18 / 23447276
kidney21 / 21177799
larynx0 / 241450 
liver13 / 20774362
lung45 / 336974133
lymph3 / 4427067
lymph node1 / 9161010
mammary gland12 / 15327178
mouth3 / 6705244
muscle5 / 10771546
nerve1 / 1576863
ovary15 / 102051146
pancreas27 / 214812125
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta38 / 280825135
prostate16 / 18934584
salivary gland33 / 201551637
skin46 / 210574218
spleen3 / 5395255
stomach1 / 9661910
testis3 / 3304429
thymus0 / 811310 
thyroid3 / 4747363
tonsil4 / 16999235
trachea1 / 5241319
umbilical cord0 / 136800 
uterus17 / 23287872
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202795_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts113.6
Adipocyte177.75
AdrenalCortex181.5
Adrenalgland113.9
Amygdala71.95
Appendix96.65
AtrioventricularNode71.75
BDCA4+_DentriticCells155.35
Bonemarrow113.15
BronchialEpithelialCells76.1
CD105+_Endothelial85.65
CD14+_Monocytes307.35
CD19+_BCells(neg._sel.)144.9
CD33+_Myeloid346.3
CD34+144.9
CD4+_Tcells97.55
CD56+_NKCells107.6
CD71+_EarlyErythroid209.15
CD8+_Tcells88.9
CardiacMyocytes301.5
Caudatenucleus47.55
Cerebellum44.9
CerebellumPeduncles46.3
CiliaryGanglion50.25
CingulateCortex58.8
Colorectaladenocarcinoma155
DorsalRootGanglion40.85
FetalThyroid363.85
Fetalbrain116.9
Fetalliver80.75
Fetallung190.95
GlobusPallidus31.5
Heart375.7
Hypothalamus55.05
Kidney57.4
Leukemia_chronicMyelogenousK-56244.55
Leukemia_promyelocytic-HL-6047.95
Leukemialymphoblastic(MOLT-4)70.4
Liver135.75
Lung352.95
Lymphnode89.35
Lymphoma_burkitts(Daudi)87.35
Lymphoma_burkitts(Raji)102.25
MedullaOblongata34.6
OccipitalLobe43.7
OlfactoryBulb96.7
Ovary100.95
Pancreas84.6
PancreaticIslet66.55
ParietalLobe37.65
Pituitary111.1
Placenta262.2
Pons45.75
PrefrontalCortex63.1
Prostate385
Salivarygland78.9
SkeletalMuscle55.6
Skin61.25
SmoothMuscle390.45
Spinalcord117.65
SubthalamicNucleus27.9
SuperiorCervicalGanglion71.05
TemporalLobe28
Testis84
TestisGermCell97.7
TestisIntersitial70.1
TestisLeydigCell103.05
TestisSeminiferousTubule106.45
Thalamus51.65
Thymus110.5
Thyroid319.65
Tongue102.4
Tonsil123.8
Trachea80.2
TrigeminalGanglion69.15
Uterus465.5
UterusCorpus76.85
WholeBlood261.65
Wholebrain44.55
colon121.1
pineal_day80.16
pineal_night76.48
retina119.875
small_intestine119.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P221885
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.07 ± 0.99
Basal Forebrain5.58 ± 0.56
Basal Part of Pons4.28 ± 0.36
Cerebellar Cortex4.46 ± 0.61
Cerebellar Nuclei4.71 ± 0.56
Claustrum5.52 ± 0.93
Epithalamus3.67 ± 0.76
Frontal Lobe4.46 ± 0.61
Globus Pallidus5.69 ± 0.47
Hypothalamus5.13 ± 0.46
Insula4.3 ± 0.43
Limbic Lobe4.87 ± 0.77
Mesencephalon5.11 ± 0.64
Myelencephalon4.71 ± 0.76
Occipital Lobe4.78 ± 0.59
Parietal Lobe4.71 ± 0.78
Pontine Tegmentum4.59 ± 0.63
Striatum4.67 ± 0.6
Subthalamus4.99 ± 0.75
Temporal Lobe4.55 ± 0.65
Thalamus4.65 ± 0.48
White Matter5.8 ± 0.71
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
TriobpCBCerebellum31.22
34.95
TriobpCTXCerebral cortex7.28
5.43
TriobpHIPHippocampal region5.97
6.49
TriobpHPFHippocampal formation5.32
5.4
TriobpHYHypothalamus2.22
2.26
TriobpLSXLateral septal complex1.55
1.2
TriobpMBMidbrain3.61
3.81
TriobpMYMedulla11.32
11.74
TriobpOLFOlfactory bulb12.31
10.45
TriobpPPons6.29
6.47
TriobpPALPallidum2.66
2.23
TriobpRHPRetrohippocampal region4.12
3.57
TriobpsAMYStriatum-like amygdalar nuclei1.57
1.44
TriobpSTRStriatum2.21
1.94
TriobpSTRdStriatum dorsal region2.2
2.02
TriobpSTRvStriatum ventral region1.69
1.11
TriobpTHThalamus15.29
12.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00011399 12 128 139 SCTDVTEYAVQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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