AutismKB 2.0

Annotation Detail for NUPL2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NUPL2 ( CG1,NLP-1,NLP_1,hCG1 )
Gene Full Name: nucleoporin like 2
Band: 7p15.3
Quick LinksEntrez ID:11097; OMIM: NA; Uniprot ID:NUPL2_HUMAN; ENSEMBL ID: ENSG00000136243; HGNC ID: 17010
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst4 / 6231964
fetus13 / 56401223
neonate0 / 310970 
infant10 / 23620423
juvenile4 / 5555671
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma3 / 8282336
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma7 / 7175597
non-neoplasia2 / 9725020
normal146 / 336030743
ovarian tumor3 / 7668239
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS26 / 125680206
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites1 / 4001524
bladder4 / 29757134
blood12 / 12347897
bone3 / 7165541
bone marrow1 / 4880120
brain44 / 110098939
cervix2 / 4817141
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue10 / 21572246
esophagus1 / 2020949
eye10 / 21105447
heart2 / 8962622
intestine6 / 23447225
kidney10 / 21177747
larynx0 / 241450 
liver9 / 20774343
lung2 / 3369745
lymph2 / 4427045
lymph node3 / 9161032
mammary gland3 / 15327119
mouth0 / 670520 
muscle0 / 1077150 
nerve2 / 15768126
ovary6 / 10205158
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta13 / 28082546
prostate12 / 18934563
salivary gland0 / 201550 
skin5 / 21057423
spleen2 / 5395237
stomach1 / 9661910
testis20 / 33044260
thymus5 / 8113161
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204003_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.45
Adipocyte8.9
AdrenalCortex9.3
Adrenalgland7.5
Amygdala10.2
Appendix11.15
AtrioventricularNode6.8
BDCA4+_DentriticCells22.75
Bonemarrow9.05
BronchialEpithelialCells8.8
CD105+_Endothelial9.3
CD14+_Monocytes19.7
CD19+_BCells(neg._sel.)32.8
CD33+_Myeloid11.75
CD34+19.2
CD4+_Tcells13.75
CD56+_NKCells12.7
CD71+_EarlyErythroid14.8
CD8+_Tcells10.6
CardiacMyocytes17.55
Caudatenucleus8.05
Cerebellum7.15
CerebellumPeduncles10.65
CiliaryGanglion6.65
CingulateCortex9.1
Colorectaladenocarcinoma34.05
DorsalRootGanglion6.8
FetalThyroid8.7
Fetalbrain9.5
Fetalliver7.65
Fetallung7.7
GlobusPallidus6.45
Heart12
Hypothalamus9.75
Kidney7.15
Leukemia_chronicMyelogenousK-5629.1
Leukemia_promyelocytic-HL-609.65
Leukemialymphoblastic(MOLT-4)7.3
Liver11.75
Lung9.3
Lymphnode11.25
Lymphoma_burkitts(Daudi)21.6
Lymphoma_burkitts(Raji)25.75
MedullaOblongata8.15
OccipitalLobe8.1
OlfactoryBulb6.8
Ovary5.85
Pancreas7.2
PancreaticIslet11.3
ParietalLobe9.4
Pituitary10.45
Placenta8.5
Pons8.45
PrefrontalCortex11.55
Prostate10.45
Salivarygland11.1
SkeletalMuscle10.25
Skin6.85
SmoothMuscle10.25
Spinalcord9.3
SubthalamicNucleus8.05
SuperiorCervicalGanglion10
TemporalLobe8.1
Testis7.75
TestisGermCell13.2
TestisIntersitial7.85
TestisLeydigCell10.15
TestisSeminiferousTubule7.75
Thalamus9.1
Thymus9.75
Thyroid17.05
Tongue8.75
Tonsil11.7
Trachea7.45
TrigeminalGanglion9.95
Uterus7.35
UterusCorpus7.95
WholeBlood9.9
Wholebrain7.7
colon13.2
pineal_day12.38
pineal_night11.7
retina11.5
small_intestine10.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6538_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.18 ± 0.25
Basal Forebrain8.93 ± 0.18
Basal Part of Pons8.81 ± 0.24
Cerebellar Cortex9.17 ± 0.2
Cerebellar Nuclei8.93 ± 0.22
Claustrum9.03 ± 0.22
Epithalamus8.76 ± 0.18
Frontal Lobe8.78 ± 0.3
Globus Pallidus8.99 ± 0.2
Hypothalamus8.76 ± 0.18
Insula8.87 ± 0.31
Limbic Lobe9.01 ± 0.36
Mesencephalon8.98 ± 0.29
Myelencephalon8.88 ± 0.25
Occipital Lobe9.27 ± 0.35
Parietal Lobe8.96 ± 0.26
Pontine Tegmentum8.92 ± 0.32
Striatum8.97 ± 0.35
Subthalamus8.71 ± 0.43
Temporal Lobe8.9 ± 0.29
Thalamus8.76 ± 0.23
White Matter9.36 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nupl2CBCerebellum5.44
6.21
Nupl2CTXCerebral cortex3.87
2.54
Nupl2HIPHippocampal region5.15
4.31
Nupl2HPFHippocampal formation5.05
3.92
Nupl2HYHypothalamus1.38
0.95
Nupl2LSXLateral septal complex0.09
0.13
Nupl2MBMidbrain2.98
3.58
Nupl2MYMedulla3.18
3.33
Nupl2OLFOlfactory bulb4.68
3.25
Nupl2PPons5.53
9.87
Nupl2PALPallidum1.65
1.2
Nupl2RHPRetrohippocampal region4.59
2.99
Nupl2sAMYStriatum-like amygdalar nuclei5.92
3.51
Nupl2STRStriatum1.95
1.55
Nupl2STRdStriatum dorsal region0.51
0.35
Nupl2STRvStriatum ventral region6.18
5.2
Nupl2THThalamus1.83
1.27
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00498253 18 74 91 DQEKPYFSSFDSGASTNR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved