AutismKB 2.0

Annotation Detail for KRR1


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Basic Information Top
Gene Symbol:KRR1 ( HRB2,RIP-1 )
Gene Full Name: KRR1, small subunit (SSU) processome component, homolog (yeast)
Band: 12q21.2
Quick LinksEntrez ID:11103; OMIM: 612817; Uniprot ID:KRR1_HUMAN; ENSEMBL ID: ENSG00000111615; HGNC ID: 5176
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst2 / 6231932
fetus17 / 56401230
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult55 / 193912128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma6 / 17475343
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma3 / 7175541
non-neoplasia1 / 9725010
normal104 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer6 / 10268058
retinoblastoma3 / 4635664
skin tumor6 / 12494948
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder6 / 29757201
blood7 / 12347856
bone2 / 7165527
bone marrow2 / 4880140
brain18 / 110098916
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus1 / 2020949
eye4 / 21105418
heart2 / 8962622
intestine9 / 23447238
kidney8 / 21177737
larynx1 / 2414541
liver8 / 20774338
lung21 / 33697462
lymph1 / 4427022
lymph node8 / 9161087
mammary gland6 / 15327139
mouth0 / 670520 
muscle4 / 10771537
nerve1 / 1576863
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta12 / 28082542
prostate5 / 18934526
salivary gland2 / 2015599
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis14 / 33044242
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203202_at
Cell line Expression level Expression bar
721_B_lymphoblasts79.35
Adipocyte7.3
AdrenalCortex8.75
Adrenalgland6.5
Amygdala9.5
Appendix9.05
AtrioventricularNode7.45
BDCA4+_DentriticCells110.65
Bonemarrow7.9
BronchialEpithelialCells11.5
CD105+_Endothelial156.6
CD14+_Monocytes13.15
CD19+_BCells(neg._sel.)61.25
CD33+_Myeloid14.7
CD34+144.2
CD4+_Tcells49.4
CD56+_NKCells90.05
CD71+_EarlyErythroid60.55
CD8+_Tcells32.25
CardiacMyocytes19.75
Caudatenucleus6.6
Cerebellum6.2
CerebellumPeduncles9
CiliaryGanglion7.5
CingulateCortex7.8
Colorectaladenocarcinoma9.7
DorsalRootGanglion6.65
FetalThyroid9.3
Fetalbrain7.65
Fetalliver6.7
Fetallung7.9
GlobusPallidus5.65
Heart10.65
Hypothalamus7.75
Kidney6.4
Leukemia_chronicMyelogenousK-5627.7
Leukemia_promyelocytic-HL-608.4
Leukemialymphoblastic(MOLT-4)10.65
Liver11.05
Lung8
Lymphnode7.15
Lymphoma_burkitts(Daudi)10.3
Lymphoma_burkitts(Raji)10.9
MedullaOblongata7.3
OccipitalLobe6.5
OlfactoryBulb5.9
Ovary6.25
Pancreas6.4
PancreaticIslet8.1
ParietalLobe8.35
Pituitary9.25
Placenta7.25
Pons7.4
PrefrontalCortex10
Prostate8.65
Salivarygland6.35
SkeletalMuscle9.4
Skin6.95
SmoothMuscle26.15
Spinalcord7.8
SubthalamicNucleus6.95
SuperiorCervicalGanglion9.45
TemporalLobe7.05
Testis5.95
TestisGermCell6.15
TestisIntersitial6.7
TestisLeydigCell7.75
TestisSeminiferousTubule6.2
Thalamus7.5
Thymus5.95
Thyroid15.55
Tongue8.45
Tonsil8.2
Trachea6.6
TrigeminalGanglion9.25
Uterus8.45
UterusCorpus7.3
WholeBlood14.45
Wholebrain6.1
colon7.65
pineal_day12.58
pineal_night16.36
retina8.125
small_intestine7.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P2216
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.14 ± 0.15
Basal Forebrain8.94 ± 0.15
Basal Part of Pons8.91 ± 0.28
Cerebellar Cortex9.22 ± 0.13
Cerebellar Nuclei8.77 ± 0.19
Claustrum9.05 ± 0.21
Epithalamus9.15 ± 0.21
Frontal Lobe8.99 ± 0.24
Globus Pallidus8.71 ± 0.19
Hypothalamus9.1 ± 0.17
Insula9.17 ± 0.27
Limbic Lobe9.1 ± 0.3
Mesencephalon9.06 ± 0.22
Myelencephalon8.99 ± 0.23
Occipital Lobe9.18 ± 0.23
Parietal Lobe9.07 ± 0.19
Pontine Tegmentum9.02 ± 0.19
Striatum8.93 ± 0.22
Subthalamus8.95 ± 0.18
Temporal Lobe9.05 ± 0.2
Thalamus8.94 ± 0.14
White Matter9.14 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Krr1CBCerebellum9.63
10.83
Krr1CTXCerebral cortex27.61
19.93
Krr1HIPHippocampal region17.96
19.46
Krr1HPFHippocampal formation18.55
17.57
Krr1HYHypothalamus4.26
3.18
Krr1LSXLateral septal complex8.32
5.09
Krr1MBMidbrain9.44
7.9
Krr1MYMedulla9.01
8.73
Krr1OLFOlfactory bulb15.57
11.98
Krr1PPons6.12
6.09
Krr1PALPallidum5.47
4.5
Krr1RHPRetrohippocampal region19.55
15.02
Krr1sAMYStriatum-like amygdalar nuclei3.2
2.05
Krr1STRStriatum6.8
4.52
Krr1STRdStriatum dorsal region7.24
5.05
Krr1STRvStriatum ventral region6.76
3.91
Krr1THThalamus13.48
10.96
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024173 24 82 105 ALNEHHVNATLDLIEGSMTVCTTK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018