AutismKB 2.0

Annotation Detail for KATNA1


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Basic Information Top
Gene Symbol:KATNA1 ( - )
Gene Full Name: katanin p60 (ATPase-containing) subunit A 1
Band: 6q25.1
Quick LinksEntrez ID:11104; OMIM: 606696; Uniprot ID:KTNA1_HUMAN; ENSEMBL ID: ENSG00000186625; HGNC ID: 6216
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus10 / 56401217
neonate0 / 310970 
infant3 / 23620127
juvenile1 / 5555617
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor7 / 26384526
glioma1 / 1068839
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor4 / 9635941
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal102 / 336030730
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor15 / 125191119
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood0 / 1234780 
bone5 / 7165569
bone marrow2 / 4880140
brain22 / 110098919
cervix1 / 4817120
connective tissue16 / 149255107
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye4 / 21105418
heart2 / 8962622
intestine1 / 2344724
kidney5 / 21177723
larynx1 / 2414541
liver8 / 20774338
lung4 / 33697411
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta9 / 28082532
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis45 / 330442136
thymus2 / 8113124
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205526_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts70
Adipocyte7.9
AdrenalCortex8.45
Adrenalgland5.35
Amygdala6.75
Appendix8.65
AtrioventricularNode7.25
BDCA4+_DentriticCells47.05
Bonemarrow6.25
BronchialEpithelialCells8.75
CD105+_Endothelial49.4
CD14+_Monocytes22.25
CD19+_BCells(neg._sel.)48.45
CD33+_Myeloid30.5
CD34+62.5
CD4+_Tcells20.85
CD56+_NKCells31.05
CD71+_EarlyErythroid105.75
CD8+_Tcells35.85
CardiacMyocytes8.85
Caudatenucleus6.2
Cerebellum5.1
CerebellumPeduncles7.6
CiliaryGanglion5.1
CingulateCortex6.8
Colorectaladenocarcinoma7.15
DorsalRootGanglion5.15
FetalThyroid6.15
Fetalbrain7.05
Fetalliver5.95
Fetallung10.9
GlobusPallidus5.1
Heart9.05
Hypothalamus11
Kidney5.6
Leukemia_chronicMyelogenousK-56223.7
Leukemia_promyelocytic-HL-6017.45
Leukemialymphoblastic(MOLT-4)24.15
Liver9
Lung7.7
Lymphnode6.65
Lymphoma_burkitts(Daudi)19.85
Lymphoma_burkitts(Raji)12.2
MedullaOblongata5.8
OccipitalLobe6.1
OlfactoryBulb5.6
Ovary5.05
Pancreas5.2
PancreaticIslet7.55
ParietalLobe7.6
Pituitary8
Placenta7.6
Pons7.75
PrefrontalCortex8.3
Prostate8.25
Salivarygland5.6
SkeletalMuscle10.3
Skin5.85
SmoothMuscle8.45
Spinalcord8.25
SubthalamicNucleus6.05
SuperiorCervicalGanglion11.35
TemporalLobe5.95
Testis38.6
TestisGermCell62.15
TestisIntersitial141.75
TestisLeydigCell60.6
TestisSeminiferousTubule60
Thalamus6.75
Thymus6.5
Thyroid12
Tongue8.05
Tonsil10.05
Trachea5.9
TrigeminalGanglion8.6
Uterus14.45
UterusCorpus6.4
WholeBlood9.55
Wholebrain5.4
colon7.8
pineal_day8.1
pineal_night8.4
retina9.225
small_intestine6.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8056_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.54 ± 0.46
Basal Forebrain5.93 ± 0.17
Basal Part of Pons5.51 ± 0.3
Cerebellar Cortex6.01 ± 0.16
Cerebellar Nuclei5.74 ± 0.35
Claustrum5.55 ± 0.6
Epithalamus6.82 ± 0.46
Frontal Lobe5.67 ± 0.41
Globus Pallidus6.43 ± 0.37
Hypothalamus6 ± 0.31
Insula5.77 ± 0.37
Limbic Lobe5.47 ± 0.38
Mesencephalon5.88 ± 0.4
Myelencephalon5.77 ± 0.46
Occipital Lobe5.78 ± 0.36
Parietal Lobe5.63 ± 0.47
Pontine Tegmentum5.88 ± 0.33
Striatum5.91 ± 0.5
Subthalamus6 ± 0.21
Temporal Lobe5.68 ± 0.33
Thalamus5.77 ± 0.34
White Matter7.03 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Katna1CBCerebellum2.23
2.71
Katna1CTXCerebral cortex1.98
1.69
Katna1HIPHippocampal region6.82
7.27
Katna1HPFHippocampal formation5.28
5.31
Katna1HYHypothalamus0.55
1.14
Katna1LSXLateral septal complex0.11
0.28
Katna1MBMidbrain0.42
0.77
Katna1MYMedulla2.26
2.45
Katna1OLFOlfactory bulb2.97
2.16
Katna1PPons1.22
1.37
Katna1PALPallidum0.55
0.57
Katna1RHPRetrohippocampal region2.61
2.5
Katna1sAMYStriatum-like amygdalar nuclei0.79
0.76
Katna1STRStriatum0.83
0.79
Katna1STRdStriatum dorsal region0.9
0.91
Katna1STRvStriatum ventral region0.83
0.52
Katna1THThalamus0.94
1.05
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00095908 18 299 316 FYSPATIFIDEIDSICSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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