Annotation Detail for CIT
Basic Information Top
| Gene Symbol: | CIT ( CRIK,KIAA0949,STK21 ) |
|---|---|
| Gene Full Name: | citron (rho-interacting, serine/threonine kinase 21) |
| Band: | 12q24.23 |
| Quick Links | Entrez ID:11113; OMIM: 605629; Uniprot ID:CTRO_HUMAN; ENSEMBL ID: ENSG00000122966; HGNC ID: 1985 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.119594
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 24 / 564012 | 42 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 75 / 1939121 | 38 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 7 / 82823 | 84 | |
| colorectal tumor | 10 / 114246 | 87 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 1 / 119369 | 8 |  |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 5 / 96359 | 51 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 115 / 3360307 | 34 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 2 / 46356 | 43 | |
| skin tumor | 9 / 124949 | 72 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 1 / 29757 | 33 | |
| blood | 4 / 123478 | 32 | |
| bone | 5 / 71655 | 69 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 66 / 1100989 | 59 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 9 / 211054 | 42 | |
| heart | 2 / 89626 | 22 | |
| intestine | 12 / 234472 | 51 | |
| kidney | 11 / 211777 | 51 | |
| larynx | 0 / 24145 | 0 | |
| liver | 7 / 207743 | 33 | |
| lung | 8 / 336974 | 23 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 8 / 102051 | 78 | |
| pancreas | 1 / 214812 | 4 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 10 / 210574 | 47 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 7 / 330442 | 21 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 6 / 232878 | 25 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 212801_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 12.1 | |
| Adipocyte | 3.25 | |
| AdrenalCortex | 3.45 | |
| Adrenalgland | 3.3 | |
| Amygdala | 36.2 | |
| Appendix | 3.45 | |
| AtrioventricularNode | 2.55 | |
| BDCA4+_DentriticCells | 3.5 | |
| Bonemarrow | 3.5 | |
| BronchialEpithelialCells | 3.15 | |
| CD105+_Endothelial | 24.75 | |
| CD14+_Monocytes | 3.55 | |
| CD19+_BCells(neg._sel.) | 3.55 | |
| CD33+_Myeloid | 5.1 | |
| CD34+ | 14.9 | |
| CD4+_Tcells | 3.75 | |
| CD56+_NKCells | 3.85 | |
| CD71+_EarlyErythroid | 25.95 | |
| CD8+_Tcells | 3.35 | |
| CardiacMyocytes | 4.35 | |
| Caudatenucleus | 21.95 | |
| Cerebellum | 3.75 | |
| CerebellumPeduncles | 4.25 | |
| CiliaryGanglion | 2.35 | |
| CingulateCortex | 43.05 | |
| Colorectaladenocarcinoma | 5.75 | |
| DorsalRootGanglion | 2.7 | |
| FetalThyroid | 3.25 | |
| Fetalbrain | 4.85 | |
| Fetalliver | 3.15 | |
| Fetallung | 2.9 | |
| GlobusPallidus | 12.5 | |
| Heart | 4.1 | |
| Hypothalamus | 20.3 | |
| Kidney | 2.65 | |
| Leukemia_chronicMyelogenousK-562 | 3.15 | |
| Leukemia_promyelocytic-HL-60 | 2.9 | |
| Leukemialymphoblastic(MOLT-4) | 24.05 | |
| Liver | 4.25 | |
| Lung | 5.5 | |
| Lymphnode | 2.85 | |
| Lymphoma_burkitts(Daudi) | 4.35 | |
| Lymphoma_burkitts(Raji) | 4.75 | |
| MedullaOblongata | 18.7 | |
| OccipitalLobe | 11 | |
| OlfactoryBulb | 3.65 | |
| Ovary | 2.15 | |
| Pancreas | 2.65 | |
| PancreaticIslet | 3.4 | |
| ParietalLobe | 10.5 | |
| Pituitary | 4 | |
| Placenta | 3.35 | |
| Pons | 10.9 | |
| PrefrontalCortex | 172.9 | |
| Prostate | 3.9 | |
| Salivarygland | 2.15 | |
| SkeletalMuscle | 3.6 | |
| Skin | 2.85 | |
| SmoothMuscle | 3.95 | |
| Spinalcord | 4.3 | |
| SubthalamicNucleus | 27.2 | |
| SuperiorCervicalGanglion | 3.85 | |
| TemporalLobe | 8.75 | |
| Testis | 4 | |
| TestisGermCell | 3.15 | |
| TestisIntersitial | 2.9 | |
| TestisLeydigCell | 3.35 | |
| TestisSeminiferousTubule | 2.95 | |
| Thalamus | 73.55 | |
| Thymus | 3.75 | |
| Thyroid | 4.05 | |
| Tongue | 3.3 | |
| Tonsil | 3.35 | |
| Trachea | 2.65 | |
| TrigeminalGanglion | 3.55 | |
| Uterus | 2.7 | |
| UterusCorpus | 2.9 | |
| WholeBlood | 3.5 | |
| Wholebrain | 20.2 | |
| colon | 3.2 | |
| pineal_day | 62.8 | |
| pineal_night | 49.98 | |
| retina | 4.4 | |
| small_intestine | 3.25 | |
- Probe name: CUST_174_PI416408490
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.59 ± 0.62 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.49 ± 0.11 | |
| Basal Part of Pons | 4.19 ± 0.34 | |
| Cerebellar Cortex | 4.24 ± 0.51 | |
| Cerebellar Nuclei | 3.99 ± 0.41 | |
| Claustrum | 4.8 ± 0.44 | |
| Epithalamus | 4.6 ± 0.68 | |
| Frontal Lobe | 4.48 ± 0.58 | |
| Globus Pallidus | 3.82 ± 0.72 | |
| Hypothalamus | 3.92 ± 0.43 | |
| Insula | 4.28 ± 0.55 | |
| Limbic Lobe | 4.53 ± 0.62 | |
| Mesencephalon | 4.51 ± 0.71 | |
| Myelencephalon | 4.65 ± 0.68 | |
| Occipital Lobe | 5.24 ± 0.57 | |
| Parietal Lobe | 5 ± 0.48 | |
| Pontine Tegmentum | 4.84 ± 0.63 | |
| Striatum | 5.36 ± 0.39 | |
| Subthalamus | 4.09 ± 0.47 | |
| Temporal Lobe | 4.74 ± 0.53 | |
| Thalamus | 5.54 ± 0.49 | |
| White Matter | 2.45 ± 0.42 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cit | CB | Cerebellum | 24.23 | |
| 27.28 | | |||
| Cit | CTX | Cerebral cortex | 100 | |
| 78.19 | | |||
| Cit | HIP | Hippocampal region | 25.72 | |
| 26.08 | | |||
| Cit | HPF | Hippocampal formation | 54.72 | |
| 44.39 | | |||
| Cit | HY | Hypothalamus | 62.87 | |
| 44.12 | | |||
| Cit | LSX | Lateral septal complex | 62.99 | |
| 38.96 | | |||
| Cit | MB | Midbrain | 72.96 | |
| 56.7 | | |||
| Cit | MY | Medulla | 63.41 | |
| 57.66 | | |||
| Cit | OLF | Olfactory bulb | 76.52 | |
| 53.92 | | |||
| Cit | P | Pons | 66.27 | |
| 56.61 | | |||
| Cit | PAL | Pallidum | 66.5 | |
| 52.87 | | |||
| Cit | RHP | Retrohippocampal region | 97.7 | |
| 69.41 | | |||
| Cit | sAMY | Striatum-like amygdalar nuclei | 63.74 | |
| 37.67 | | |||
| Cit | STR | Striatum | 89.55 | |
| 54.46 | | |||
| Cit | STRd | Striatum dorsal region | 100 | |
| 63.63 | | |||
| Cit | STRv | Striatum ventral region | 69.77 | |
| 40.99 | | |||
| Cit | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CTRO_HUMAN_431 | 13 | 431 | 443 | SESVVSGLDSPAK | PRIDE |
| CTRO_HUMAN_581 | 10 | 581 | 590 | RSDLYESELR | PRIDE |
| CTRO_HUMAN_875 | 12 | 875 | 886 | QLTELQLSLQER | PRIDE |
| PAp00065751 | 14 | 702 | 715 | EAQVSAQHLEVHLK | Peptide Atlas |