AutismKB 2.0

Annotation Detail for FOXN3


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Basic Information Top
Gene Symbol:FOXN3 ( C14orf116,CHES1,PRO1635 )
Gene Full Name: forkhead box N3
Band: 14q31.3-q32.11
Quick LinksEntrez ID:1112; OMIM: 602628; Uniprot ID:FOXN3_HUMAN; ENSEMBL ID: ENSG00000053254; HGNC ID: 1928
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst5 / 6231980
fetus83 / 564012147
neonate0 / 310970 
infant1 / 2362042
juvenile8 / 55556143
adult151 / 193912177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor17 / 26384564
glioma10 / 10688393
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia19 / 95842198
liver tumor2 / 9635920
lung tumor7 / 10312767
lymphoma14 / 71755195
non-neoplasia6 / 9725061
normal323 / 336030796
ovarian tumor18 / 76682234
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer7 / 10268068
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood6 / 12347848
bone6 / 7165583
bone marrow16 / 48801327
brain54 / 110098949
cervix0 / 481710 
connective tissue8 / 14925553
ear1 / 1621261
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye29 / 211054137
heart9 / 89626100
intestine20 / 23447285
kidney14 / 21177766
larynx1 / 2414541
liver12 / 20774357
lung33 / 33697497
lymph4 / 4427090
lymph node51 / 91610556
mammary gland7 / 15327145
mouth2 / 6705229
muscle16 / 107715148
nerve0 / 157680 
ovary19 / 102051186
pancreas9 / 21481241
parathyroid6 / 20539292
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta11 / 28082539
prostate8 / 18934542
salivary gland1 / 2015549
skin27 / 210574128
spleen3 / 5395255
stomach11 / 96619113
testis12 / 33044236
thymus2 / 8113124
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218031_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts33.85
Adipocyte91
AdrenalCortex11.15
Adrenalgland8.9
Amygdala9.25
Appendix23.1
AtrioventricularNode6.4
BDCA4+_DentriticCells80.15
Bonemarrow9
BronchialEpithelialCells8.15
CD105+_Endothelial12.95
CD14+_Monocytes53.4
CD19+_BCells(neg._sel.)128.15
CD33+_Myeloid179.9
CD34+125.9
CD4+_Tcells109.1
CD56+_NKCells220.65
CD71+_EarlyErythroid32.5
CD8+_Tcells108.5
CardiacMyocytes8.85
Caudatenucleus5.75
Cerebellum86.75
CerebellumPeduncles115.05
CiliaryGanglion6.1
CingulateCortex8.55
Colorectaladenocarcinoma34.2
DorsalRootGanglion6.35
FetalThyroid6.85
Fetalbrain19.55
Fetalliver17.4
Fetallung17.1
GlobusPallidus6.4
Heart9.35
Hypothalamus10.85
Kidney7.1
Leukemia_chronicMyelogenousK-5626.2
Leukemia_promyelocytic-HL-606.8
Leukemialymphoblastic(MOLT-4)29.6
Liver7.9
Lung9.15
Lymphnode11.8
Lymphoma_burkitts(Daudi)11.1
Lymphoma_burkitts(Raji)10.6
MedullaOblongata7.7
OccipitalLobe7.8
OlfactoryBulb9.35
Ovary33.95
Pancreas5.25
PancreaticIslet13.05
ParietalLobe8.85
Pituitary9.55
Placenta15.85
Pons6.95
PrefrontalCortex18.45
Prostate10.2
Salivarygland12.85
SkeletalMuscle10.6
Skin6.15
SmoothMuscle10.2
Spinalcord8.85
SubthalamicNucleus7.8
SuperiorCervicalGanglion9.95
TemporalLobe6.7
Testis5.05
TestisGermCell11
TestisIntersitial4.95
TestisLeydigCell5.5
TestisSeminiferousTubule4.1
Thalamus6.3
Thymus22.5
Thyroid9.95
Tongue9
Tonsil14.65
Trachea22.65
TrigeminalGanglion5.85
Uterus43.25
UterusCorpus9.25
WholeBlood169.3
Wholebrain7.4
colon29.4
pineal_day56.62
pineal_night41.4
retina44.05
small_intestine115.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P140405
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.55 ± 0.26
Basal Forebrain10.74 ± 0.31
Basal Part of Pons10.28 ± 0.29
Cerebellar Cortex11.05 ± 0.3
Cerebellar Nuclei10.9 ± 0.23
Claustrum10.88 ± 0.35
Epithalamus10.31 ± 0.53
Frontal Lobe10.49 ± 0.37
Globus Pallidus10.72 ± 0.34
Hypothalamus10.45 ± 0.24
Insula10.37 ± 0.23
Limbic Lobe10.25 ± 0.34
Mesencephalon10.63 ± 0.31
Myelencephalon10.57 ± 0.36
Occipital Lobe10.87 ± 0.37
Parietal Lobe10.61 ± 0.29
Pontine Tegmentum10.64 ± 0.36
Striatum10.49 ± 0.42
Subthalamus10.92 ± 0.41
Temporal Lobe10.45 ± 0.27
Thalamus10.75 ± 0.35
White Matter10.51 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ches1CBCerebellum0
0
Ches1CTXCerebral cortex0
0
Ches1HIPHippocampal region0
0
Ches1HPFHippocampal formation0
0
Ches1HYHypothalamus0
0
Ches1LSXLateral septal complex0
0
Ches1MBMidbrain0
0
Ches1MYMedulla0
0
Ches1OLFOlfactory bulb0
0
Ches1PPons0
0
Ches1PALPallidum0
0
Ches1RHPRetrohippocampal region0
0
Ches1sAMYStriatum-like amygdalar nuclei0
0
Ches1STRStriatum0
0
Ches1STRdStriatum dorsal region0
0
Ches1STRvStriatum ventral region0
0
Ches1THThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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