AutismKB 2.0

Annotation Detail for PWP1


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Basic Information Top
Gene Symbol:PWP1 ( IEF-SSP-9502 )
Gene Full Name: PWP1 homolog (S. cerevisiae)
Band: 12q23.3
Quick LinksEntrez ID:11137; OMIM: NA; Uniprot ID:PWP1_HUMAN; ENSEMBL ID: ENSG00000136045; HGNC ID: 17015
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst6 / 6231996
fetus62 / 564012109
neonate3 / 3109796
infant7 / 23620296
juvenile9 / 55556161
adult116 / 193912159
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor4 / 34366116
chondrosarcoma6 / 8282372
colorectal tumor7 / 11424661
esophageal tumor2 / 17290115
gastrointestinal tumor3 / 11936925
germ cell tumor34 / 263845128
glioma6 / 10688356
head and neck tumor3 / 13630222
kidney tumor11 / 68959159
leukemia15 / 95842156
liver tumor23 / 96359238
lung tumor12 / 103127116
lymphoma7 / 7175597
non-neoplasia3 / 9725030
normal292 / 336030786
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor58 / 124949464
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor14 / 90257155
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder3 / 29757100
blood17 / 123478137
bone5 / 7165569
bone marrow3 / 4880161
brain103 / 110098993
cervix5 / 48171103
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus2 / 2020998
eye15 / 21105471
heart9 / 89626100
intestine22 / 23447293
kidney33 / 211777155
larynx0 / 241450 
liver28 / 207743134
lung46 / 336974136
lymph1 / 4427022
lymph node7 / 9161076
mammary gland9 / 15327158
mouth2 / 6705229
muscle5 / 10771546
nerve0 / 157680 
ovary9 / 10205188
pancreas16 / 21481274
parathyroid1 / 2053948
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta29 / 280825103
prostate5 / 18934526
salivary gland0 / 201550 
skin64 / 210574303
spleen1 / 5395218
stomach11 / 96619113
testis26 / 33044278
thymus3 / 8113136
thyroid2 / 4747342
tonsil6 / 16999352
trachea1 / 5241319
umbilical cord2 / 13680146
uterus28 / 232878120
vascular7 / 51780135
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201606_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts538.25
Adipocyte55.1
AdrenalCortex16.75
Adrenalgland37.55
Amygdala52.35
Appendix9.75
AtrioventricularNode12.1
BDCA4+_DentriticCells350.9
Bonemarrow26.8
BronchialEpithelialCells262.65
CD105+_Endothelial378.75
CD14+_Monocytes162.1
CD19+_BCells(neg._sel.)745.45
CD33+_Myeloid174.35
CD34+503.85
CD4+_Tcells257.4
CD56+_NKCells500.15
CD71+_EarlyErythroid49
CD8+_Tcells243.7
CardiacMyocytes101.75
Caudatenucleus12.45
Cerebellum9.2
CerebellumPeduncles40.55
CiliaryGanglion8.5
CingulateCortex45.05
Colorectaladenocarcinoma108.15
DorsalRootGanglion16.45
FetalThyroid49
Fetalbrain41.45
Fetalliver42.4
Fetallung31.6
GlobusPallidus16.85
Heart10.5
Hypothalamus38.85
Kidney30.4
Leukemia_chronicMyelogenousK-56251.4
Leukemia_promyelocytic-HL-6048.1
Leukemialymphoblastic(MOLT-4)52.6
Liver62.95
Lung107.2
Lymphnode20.65
Lymphoma_burkitts(Daudi)49.05
Lymphoma_burkitts(Raji)65
MedullaOblongata35.05
OccipitalLobe48.7
OlfactoryBulb41.25
Ovary23
Pancreas34
PancreaticIslet36.25
ParietalLobe22.25
Pituitary56.75
Placenta51.2
Pons21.85
PrefrontalCortex106
Prostate126.8
Salivarygland9.25
SkeletalMuscle13.9
Skin11.05
SmoothMuscle191.75
Spinalcord13.65
SubthalamicNucleus39.8
SuperiorCervicalGanglion7.4
TemporalLobe50.55
Testis78.25
TestisGermCell56.6
TestisIntersitial50.15
TestisLeydigCell34.55
TestisSeminiferousTubule41.45
Thalamus14.5
Thymus131.55
Thyroid62
Tongue32.85
Tonsil27.65
Trachea33.2
TrigeminalGanglion17.15
Uterus98.35
UterusCorpus12.55
WholeBlood38.25
Wholebrain49.6
colon72.4
pineal_day199.02
pineal_night163.58
retina99.425
small_intestine103.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2275_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.41 ± 0.29
Basal Forebrain7.49 ± 0.19
Basal Part of Pons7.71 ± 0.2
Cerebellar Cortex7.83 ± 0.11
Cerebellar Nuclei7.51 ± 0.15
Claustrum7.43 ± 0.28
Epithalamus7.63 ± 0.11
Frontal Lobe7.66 ± 0.23
Globus Pallidus7.25 ± 0.16
Hypothalamus7.76 ± 0.24
Insula7.73 ± 0.16
Limbic Lobe7.5 ± 0.29
Mesencephalon7.53 ± 0.27
Myelencephalon7.54 ± 0.31
Occipital Lobe7.34 ± 0.27
Parietal Lobe7.56 ± 0.24
Pontine Tegmentum7.55 ± 0.23
Striatum7.23 ± 0.25
Subthalamus7.75 ± 0.14
Temporal Lobe7.68 ± 0.23
Thalamus7.52 ± 0.28
White Matter7.66 ± 0.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pwp1CBCerebellum0.5
0.77
Pwp1CTXCerebral cortex1.17
1.1
Pwp1HIPHippocampal region3.68
3.15
Pwp1HPFHippocampal formation3.17
2.66
Pwp1HYHypothalamus3.52
3.7
Pwp1LSXLateral septal complex0.11
0.07
Pwp1MBMidbrain0.35
1.1
Pwp1MYMedulla1.02
2.13
Pwp1OLFOlfactory bulb10.71
9.77
Pwp1PPons1.54
2.45
Pwp1PALPallidum1.21
1.96
Pwp1RHPRetrohippocampal region1.95
1.71
Pwp1sAMYStriatum-like amygdalar nuclei1.7
1.19
Pwp1STRStriatum1.26
1.06
Pwp1STRdStriatum dorsal region0.35
0.35
Pwp1STRvStriatum ventral region5.45
4.27
Pwp1THThalamus0.38
0.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009864 23 134 156 DTEQYEREDFLIKPSDNLIVCGR Peptide Atlas
PWP1_HUMAN_72 14 72 85 PREPLEDGDPEDDR PRIDE
PWP1_HUMAN_74 26 74 99 EPLEDGDPEDDRTLDDDELAEYDLDK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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