AutismKB 2.0

Annotation Detail for PLA2G16


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Basic Information Top
Gene Symbol:PLA2G16 ( AdPLA,H-REV107-1,HRASLS3,HREV107,HREV107-3,MGC118754 )
Gene Full Name: phospholipase A2, group XVI
Band: 11q12.3-q13.1
Quick LinksEntrez ID:11145; OMIM: NA; Uniprot ID:PAG16_HUMAN; ENSEMBL ID: ENSG00000176485; HGNC ID: 17825
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus10 / 56401217
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult80 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor12 / 114246105
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor4 / 26384515
glioma5 / 10688346
head and neck tumor4 / 13630229
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal155 / 336030746
ovarian tumor3 / 7668239
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood0 / 1234780 
bone4 / 7165555
bone marrow0 / 488010 
brain123 / 1100989111
cervix1 / 4817120
connective tissue2 / 14925513
ear2 / 16212123
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye7 / 21105433
heart3 / 8962633
intestine19 / 23447281
kidney11 / 21177751
larynx1 / 2414541
liver4 / 20774319
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle3 / 10771527
nerve3 / 15768190
ovary3 / 10205129
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta11 / 28082539
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach5 / 9661951
testis8 / 33044224
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus7 / 23287830
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209581_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.35
Adipocyte495.9
AdrenalCortex16.45
Adrenalgland52.1
Amygdala208.35
Appendix21.95
AtrioventricularNode13.8
BDCA4+_DentriticCells186.3
Bonemarrow13.65
BronchialEpithelialCells9.95
CD105+_Endothelial8.6
CD14+_Monocytes55.1
CD19+_BCells(neg._sel.)9.55
CD33+_Myeloid30.15
CD34+5.5
CD4+_Tcells11.4
CD56+_NKCells87.2
CD71+_EarlyErythroid12.1
CD8+_Tcells10.8
CardiacMyocytes21.25
Caudatenucleus149.8
Cerebellum34.45
CerebellumPeduncles101.3
CiliaryGanglion30.85
CingulateCortex83.55
Colorectaladenocarcinoma35.4
DorsalRootGanglion49.6
FetalThyroid24.25
Fetalbrain13.3
Fetalliver13.8
Fetallung16.75
GlobusPallidus15.1
Heart280.25
Hypothalamus567.55
Kidney84.75
Leukemia_chronicMyelogenousK-56217.15
Leukemia_promyelocytic-HL-609.85
Leukemialymphoblastic(MOLT-4)8.5
Liver329.85
Lung124.1
Lymphnode21.45
Lymphoma_burkitts(Daudi)15.65
Lymphoma_burkitts(Raji)20.7
MedullaOblongata142.8
OccipitalLobe189.95
OlfactoryBulb432
Ovary29.45
Pancreas51.2
PancreaticIslet72.35
ParietalLobe264.45
Pituitary82.3
Placenta165.8
Pons62.15
PrefrontalCortex273.05
Prostate24.15
Salivarygland19.1
SkeletalMuscle24.85
Skin11.95
SmoothMuscle21.35
Spinalcord618.35
SubthalamicNucleus21.35
SuperiorCervicalGanglion16.7
TemporalLobe42
Testis299.85
TestisGermCell271
TestisIntersitial147.55
TestisLeydigCell118.35
TestisSeminiferousTubule134.65
Thalamus327.65
Thymus19.55
Thyroid94.45
Tongue15.2
Tonsil10.75
Trachea44.25
TrigeminalGanglion17.25
Uterus20.15
UterusCorpus15.55
WholeBlood23.85
Wholebrain361.95
colon21.9
pineal_day112.74
pineal_night123.98
retina326.825
small_intestine35.05
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P116414
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.92 ± 0.57
Basal Forebrain11.85 ± 0.44
Basal Part of Pons11.43 ± 0.47
Cerebellar Cortex11.03 ± 0.23
Cerebellar Nuclei12.47 ± 0.69
Claustrum11.05 ± 0.54
Epithalamus12.18 ± 0.43
Frontal Lobe11.49 ± 0.73
Globus Pallidus13.1 ± 0.27
Hypothalamus11.72 ± 0.5
Insula11.19 ± 0.33
Limbic Lobe10.95 ± 0.6
Mesencephalon11.68 ± 0.68
Myelencephalon11.55 ± 0.54
Occipital Lobe11.12 ± 0.64
Parietal Lobe11.32 ± 0.62
Pontine Tegmentum11.64 ± 0.36
Striatum12.02 ± 0.5
Subthalamus12 ± 0.49
Temporal Lobe11.29 ± 0.54
Thalamus11.85 ± 0.44
White Matter14.12 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Hrasls3CBCerebellum100
100
Hrasls3CTXCerebral cortex100
100
Hrasls3HIPHippocampal region100
100
Hrasls3HPFHippocampal formation100
100
Hrasls3HYHypothalamus100
78.93
Hrasls3LSXLateral septal complex100
54.43
Hrasls3MBMidbrain100
100
Hrasls3MYMedulla100
100
Hrasls3OLFOlfactory bulb100
100
Hrasls3PPons100
100
Hrasls3PALPallidum100
78.01
Hrasls3RHPRetrohippocampal region100
100
Hrasls3sAMYStriatum-like amygdalar nuclei99.88
55.54
Hrasls3STRStriatum94.51
51.81
Hrasls3STRdStriatum dorsal region81.51
45.34
Hrasls3STRvStriatum ventral region100
69.42
Hrasls3THThalamus100
98.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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