AutismKB 2.0

Annotation Detail for CORO1A


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Basic Information Top
Gene Symbol:CORO1A ( CLABP,CLIPINA,FLJ41407,HCORO1,MGC117380,TACO,p57 )
Gene Full Name: coronin, actin binding protein, 1A
Band: 16p11.2
Quick LinksEntrez ID:11151; OMIM: 605000; Uniprot ID:COR1A_HUMAN; ENSEMBL ID: ENSG00000102879; HGNC ID: 2252
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus63 / 564012111
neonate18 / 31097578
infant3 / 23620127
juvenile45 / 55556809
adult221 / 1939121113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor3 / 11424626
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor33 / 263845125
glioma10 / 10688393
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia67 / 95842699
liver tumor2 / 9635920
lung tumor14 / 103127135
lymphoma110 / 717551532
non-neoplasia43 / 97250442
normal602 / 3360307179
ovarian tumor2 / 7668226
pancreatic tumor32 / 104616305
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer4 / 10268038
retinoblastoma4 / 4635686
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood132 / 1234781069
bone4 / 7165555
bone marrow7 / 48801143
brain146 / 1100989132
cervix1 / 4817120
connective tissue25 / 149255167
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus2 / 2020998
eye10 / 21105447
heart6 / 8962666
intestine43 / 234472183
kidney5 / 21177723
larynx0 / 241450 
liver6 / 20774328
lung28 / 33697483
lymph77 / 442701739
lymph node44 / 91610480
mammary gland9 / 15327158
mouth2 / 6705229
muscle3 / 10771527
nerve1 / 1576863
ovary4 / 10205139
pancreas35 / 214812162
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta31 / 280825110
prostate5 / 18934526
salivary gland0 / 201550 
skin3 / 21057414
spleen85 / 539521575
stomach12 / 96619124
testis5 / 33044215
thymus279 / 811313438
thyroid0 / 474730 
tonsil94 / 169995529
trachea3 / 5241357
umbilical cord0 / 136800 
uterus30 / 232878128
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209083_at
Cell line Expression level Expression bar
721_B_lymphoblasts2311.8
Adipocyte4.7
AdrenalCortex5.5
Adrenalgland3.95
Amygdala13.6
Appendix4.55
AtrioventricularNode3
BDCA4+_DentriticCells1815.2
Bonemarrow219.35
BronchialEpithelialCells5.55
CD105+_Endothelial14.1
CD14+_Monocytes1624
CD19+_BCells(neg._sel.)1357.2
CD33+_Myeloid1735.9
CD34+362.55
CD4+_Tcells2171.55
CD56+_NKCells2003.05
CD71+_EarlyErythroid4.9
CD8+_Tcells1795.55
CardiacMyocytes5.75
Caudatenucleus5.1
Cerebellum7.25
CerebellumPeduncles7.5
CiliaryGanglion3.1
CingulateCortex5.8
Colorectaladenocarcinoma5.6
DorsalRootGanglion3.7
FetalThyroid5
Fetalbrain14.75
Fetalliver4.7
Fetallung8.1
GlobusPallidus5.2
Heart33.2
Hypothalamus6.35
Kidney4.7
Leukemia_chronicMyelogenousK-5625
Leukemia_promyelocytic-HL-6054.2
Leukemialymphoblastic(MOLT-4)236.5
Liver9.95
Lung20.4
Lymphnode210.5
Lymphoma_burkitts(Daudi)548.55
Lymphoma_burkitts(Raji)214.7
MedullaOblongata5.15
OccipitalLobe6.35
OlfactoryBulb4.45
Ovary3.15
Pancreas4.15
PancreaticIslet4.9
ParietalLobe8.1
Pituitary6.2
Placenta6.1
Pons5.4
PrefrontalCortex8.5
Prostate6.6
Salivarygland8.15
SkeletalMuscle6.2
Skin3.55
SmoothMuscle5.45
Spinalcord9.2
SubthalamicNucleus4.75
SuperiorCervicalGanglion5.85
TemporalLobe6.35
Testis3.8
TestisGermCell4.25
TestisIntersitial3.7
TestisLeydigCell4.7
TestisSeminiferousTubule4
Thalamus5
Thymus361.3
Thyroid6.7
Tongue4.8
Tonsil263.85
Trachea4
TrigeminalGanglion5.3
Uterus3.9
UterusCorpus4.65
WholeBlood2308.55
Wholebrain29.55
colon4.9
pineal_day6.3
pineal_night6.1
retina6.525
small_intestine7.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P106761
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.31 ± 0.42
Basal Forebrain6.78 ± 0.27
Basal Part of Pons7.24 ± 0.36
Cerebellar Cortex6.84 ± 0.4
Cerebellar Nuclei6.55 ± 0.39
Claustrum7.06 ± 0.36
Epithalamus6.42 ± 0.24
Frontal Lobe7.12 ± 0.5
Globus Pallidus6.19 ± 0.38
Hypothalamus6.69 ± 0.49
Insula7.25 ± 0.35
Limbic Lobe7.06 ± 0.52
Mesencephalon6.74 ± 0.57
Myelencephalon6.96 ± 0.58
Occipital Lobe6.33 ± 0.53
Parietal Lobe6.79 ± 0.48
Pontine Tegmentum6.65 ± 0.58
Striatum6.13 ± 0.58
Subthalamus6.57 ± 0.74
Temporal Lobe7.21 ± 0.46
Thalamus6.67 ± 0.5
White Matter5.92 ± 0.42
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Coro1aCBCerebellum2.77
3.59
Coro1aCTXCerebral cortex18.25
15.05
Coro1aHIPHippocampal region19.7
21.46
Coro1aHPFHippocampal formation21.14
21.04
Coro1aHYHypothalamus1.59
2.38
Coro1aLSXLateral septal complex0
0
Coro1aMBMidbrain0.54
1.04
Coro1aMYMedulla3.14
4.7
Coro1aOLFOlfactory bulb18.88
23.87
Coro1aPPons1.92
3.02
Coro1aPALPallidum0.76
0.79
Coro1aRHPRetrohippocampal region25.08
21.61
Coro1asAMYStriatum-like amygdalar nuclei2.51
2.03
Coro1aSTRStriatum1.49
1.37
Coro1aSTRdStriatum dorsal region1
1.02
Coro1aSTRvStriatum ventral region2.98
2.34
Coro1aTHThalamus4.71
4.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
COR1A_HUMAN_1 7 1 7 MSRQVVR PRIDE
COR1A_HUMAN_121 12 121 132 EPVVTLEGHTKR PRIDE
COR1A_HUMAN_186 10 186 195 DGGLICTSCR PRIDE
COR1A_HUMAN_206 19 206 224 KGTVVAEKDRPHEGTRPVR PRIDE
COR1A_HUMAN_245 8 245 252 QVALWDTK PRIDE
COR1A_HUMAN_29 16 29 44 VSQTTWDSGFCAVNPK PRIDE
COR1A_HUMAN_293 20 293 312 YFEITSEAPFLHYLSMFSSK PRIDE
COR1A_HUMAN_324 12 324 335 RGLEVNKCEIAR PRIDE
COR1A_HUMAN_325 11 325 335 GLEVNKCEIAR PRIDE
COR1A_HUMAN_337 7 337 343 FYKLHER PRIDE
COR1A_HUMAN_344 10 344 353 CEPIAMTVPR PRIDE
COR1A_HUMAN_354 29 354 382 KSDLFQEDLYPPTAGPDPALTAEEWLGGR PRIDE
COR1A_HUMAN_383 10 383 392 DAGPLLISLK PRIDE
COR1A_HUMAN_383 17 383 399 DAGPLLISLKDGYVPPK PRIDE
COR1A_HUMAN_416 16 416 431 AAPEASGTPSSDAVSR PRIDE
COR1A_HUMAN_416 22 416 437 AAPEASGTPSSDAVSRLEEEMR PRIDE
COR1A_HUMAN_438 11 438 448 KLQATVQELQK PRIDE
COR1A_HUMAN_439 10 439 448 LQATVQELQK PRIDE
COR1A_HUMAN_439 12 439 450 KLQATVQELQKR PRIDE
COR1A_HUMAN_449 12 449 460 RLDRLEETVQAK PRIDE
COR1A_HUMAN_45 21 45 65 FVALICEASGGGAFLVLPLGK PRIDE
PAp00000264 9 21 29 ADQCYEDVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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