AutismKB 2.0

Annotation Detail for NUDT6


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Basic Information Top
Gene Symbol:NUDT6 ( ASFGF2,FGF-2,FGF-AS,FGF2AS,bFGF,gfg,gfg-1 )
Gene Full Name: nudix (nucleoside diphosphate linked moiety X)-type motif 6
Band: 4q28.1
Quick LinksEntrez ID:11162; OMIM: 606261; Uniprot ID:NUDT6_HUMAN; ENSEMBL ID: ENSG00000170917; HGNC ID: 8053
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult35 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor1 / 2638453
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor3 / 9635931
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal40 / 336030711
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor20 / 125191159
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone2 / 7165527
bone marrow2 / 4880140
brain8 / 11009897
cervix0 / 481710 
connective tissue20 / 149255133
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine2 / 2344728
kidney7 / 21177733
larynx0 / 241450 
liver6 / 20774328
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate4 / 18934521
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220183_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.15
Adipocyte6.15
AdrenalCortex7.35
Adrenalgland5.4
Amygdala6.2
Appendix7.2
AtrioventricularNode5.75
BDCA4+_DentriticCells6.15
Bonemarrow6.7
BronchialEpithelialCells6.15
CD105+_Endothelial6.05
CD14+_Monocytes6.45
CD19+_BCells(neg._sel.)6.25
CD33+_Myeloid7.45
CD34+7.7
CD4+_Tcells6.25
CD56+_NKCells8
CD71+_EarlyErythroid5.9
CD8+_Tcells5.6
CardiacMyocytes9.5
Caudatenucleus5.4
Cerebellum4.95
CerebellumPeduncles7.3
CiliaryGanglion5.1
CingulateCortex6.45
Colorectaladenocarcinoma10.3
DorsalRootGanglion5.25
FetalThyroid6.05
Fetalbrain5.85
Fetalliver6.6
Fetallung4.7
GlobusPallidus4.8
Heart9.6
Hypothalamus6.35
Kidney5.45
Leukemia_chronicMyelogenousK-5625.7
Leukemia_promyelocytic-HL-605.5
Leukemialymphoblastic(MOLT-4)9.9
Liver9.75
Lung6.6
Lymphnode5
Lymphoma_burkitts(Daudi)8.05
Lymphoma_burkitts(Raji)9.3
MedullaOblongata5.5
OccipitalLobe5.4
OlfactoryBulb4.85
Ovary4.45
Pancreas5.1
PancreaticIslet6.55
ParietalLobe6.85
Pituitary7.15
Placenta6.1
Pons6.05
PrefrontalCortex7.3
Prostate6.95
Salivarygland5.1
SkeletalMuscle8.6
Skin5.45
SmoothMuscle6.85
Spinalcord6.5
SubthalamicNucleus5.8
SuperiorCervicalGanglion8.35
TemporalLobe5.75
Testis5.25
TestisGermCell4.9
TestisIntersitial5.25
TestisLeydigCell6.3
TestisSeminiferousTubule5.25
Thalamus6.3
Thymus4.65
Thyroid9.45
Tongue6.65
Tonsil6
Trachea5.1
TrigeminalGanglion7.35
Uterus4.9
UterusCorpus6.1
WholeBlood6.6
Wholebrain4.9
colon7
pineal_day7.58
pineal_night7.48
retina7.425
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9971_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.32 ± 0.62
Basal Forebrain3.6 ± 0.28
Basal Part of Pons3.6 ± 0.58
Cerebellar Cortex3.69 ± 0.55
Cerebellar Nuclei4.18 ± 0.55
Claustrum4.26 ± 0.56
Epithalamus3.52 ± 0.48
Frontal Lobe3.8 ± 0.55
Globus Pallidus4.39 ± 0.31
Hypothalamus3.78 ± 0.4
Insula3.79 ± 0.46
Limbic Lobe3.91 ± 0.6
Mesencephalon4.11 ± 0.64
Myelencephalon3.99 ± 0.57
Occipital Lobe4.06 ± 0.65
Parietal Lobe3.91 ± 0.58
Pontine Tegmentum3.92 ± 0.56
Striatum4.34 ± 0.41
Subthalamus3.51 ± 0.18
Temporal Lobe3.93 ± 0.57
Thalamus3.92 ± 0.56
White Matter4.26 ± 0.25
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nudt6CBCerebellum20.73
36.24
Nudt6CTXCerebral cortex14.54
11.59
Nudt6HIPHippocampal region1.69
1.8
Nudt6HPFHippocampal formation1.52
2.08
Nudt6HYHypothalamus0.11
0.31
Nudt6LSXLateral septal complex2.23
5.34
Nudt6MBMidbrain3.31
3.91
Nudt6MYMedulla1.38
2.24
Nudt6OLFOlfactory bulb10.24
11.11
Nudt6PPons0.49
1.03
Nudt6PALPallidum0.98
1.15
Nudt6RHPRetrohippocampal region1.39
2.35
Nudt6sAMYStriatum-like amygdalar nuclei0.26
0.31
Nudt6STRStriatum1.31
1.14
Nudt6STRdStriatum dorsal region0.47
0.37
Nudt6STRvStriatum ventral region4.99
3.42
Nudt6THThalamus0.95
0.97
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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